Role of Ras Isoforms in the Stimulated Proliferation of Human Renal Fibroblasts in Primary Culture

Use of an Aqueous Soluble Tetrazolium/Formazan Assay for Cell Growth Assays in Culture

1991 • 1,459 citations

The ras gene family and human carcinogenesis

1988 • 786 citations

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

1994 • 523 citations

Ras Isoforms Vary in Their Ability to Activate Raf-1 and Phosphoinositide 3-Kinase

1998 • 475 citations

TGF-β in kidney fibrosis: A target for gene therapy

1997 • 382 citations

Four Human Ras Homologs Differ in Their Abilities to Activate Raf-1, Induce Transformation, and Stimulate Cell Motility

1999 • 285 citations

G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts

1997 • 233 citations

New Insights into the Interaction of Ras with the Plasma Membrane

1999 • 154 citations

Therapeutic approaches to organ fibrosis

1997 • 127 citations

The significance of DNA and protein adducts in human biomonitoring studies

1988 • 126 citations

Epidermal Growth Factor Regulates the Exchange Rate of Guanine Nucleotides on p21^ras in Fibroblasts

1993 • 117 citations

Role of Platelet-Derived Growth Factor in Renal Injury

1995 • 103 citations

Renal fibrosis: Insights into pathogenesis and treatment

1997 • 92 citations

Ras-GRF Activates Ha-Ras, but Not N-Ras or K-Ras 4B, Proteinin Vivo

1998 • 91 citations

Distinct Mechanisms Mediate the Initial and Sustained Phases of Integrin-mediated Activation of the Raf/MEK/Mitogen-activated Protein Kinase Cascade

1998 • 81 citations

Progressive Renal Disease: Fibroblasts, Extracellular Matrix, and Integrins

1999 • 75 citations

Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo

1998 • 73 citations

Antisense Oligonucleotides Demonstrate a Dominant Role of c-Ki-RAS Proteins in Regulating the Proliferation of Diploid Human Fibroblasts

1996 • 73 citations

p21ras: An oncoprotein functioning in growth factor-induced signal transduction

1995 • 65 citations

Transforming growth factor α activates Ha-Ras in human pancreatic cancer cells with Ki-ras mutations☆, ☆☆

1999 • 58 citations

Differential response of the Ras exchange factor, Ras-GRF to tyrosine kinase and G protein mediated signals.

1995 • 58 citations

First- and second-generation antisense inhibitors targeted to human c-raf kinase: in vitro and in vivo studies.

1997 • 51 citations

Cytokines, growth factors and renal injury: where do we go now?

1997 • 46 citations

Demonstration of collagen type VI and alpha-smooth muscle actin in renal fibrotic injury in man.

1998 • 35 citations

Evidence of a Role for Ki-RAS in the Stimulated Proliferation of Renal Fibroblasts

1999 • 25 citations

Abnormal Growth and Clonal Proliferation of Fibroblasts in an Animal Model of Unilateral Ureteral Obstruction

1999 • 20 citations

Molecular basis of targeted chemotherapy: Novel concepts with special reference to the treatment of Hodgkin’s disease

1998 • 7 citations

Gene therapy for renal fibroblasts

1999 • 3 citations