Permanent Survival of Fully MHC-Mismatched Islet Allografts by Targeting a Single Chemokine Receptor Pathway

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

2000 • 5,125 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection

2000 • 619 citations

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in theplt/pltmouse

2000 • 580 citations

Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

1990 • 561 citations

Quantifying the Frequency of Alloreactive T Cells In Vivo: New Answers to an Old Question

2001 • 519 citations

Immunologic ‘ignorance’ of vascularized organ transplants in the absence of secondary lymphoid tissue

2000 • 446 citations

The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules

2000 • 420 citations

Initiation of Immune Responses by Small Lymphocytes

1962 • 407 citations

Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection

2000 • 255 citations

The Reduced Expression of 6ckine in the plt Mouse Results from the Deletion of One of Two 6ckine Genes

1999 • 217 citations

The Origin and Mechanism of the Allograft Reaction

1977 • 217 citations

Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody.

1984 • 216 citations

Gene Duplications at the Chemokine Locus on Mouse Chromosome 4: Multiple Strain-Specific Haplotypes and the Deletion of Secondary Lymphoid-Organ Chemokine and EBI-1 Ligand Chemokine Genes in thepltMutation

2001 • 210 citations

Cutting Edge: Identification of a Novel Chemokine Receptor That Binds Dendritic Cell- and T Cell-Active Chemokines Including ELC, SLC, and TECK

2000 • 202 citations

Mice Lacking Expression of the Chemokines Ccl21-Ser and Ccl19 (plt Mice) Demonstrate Delayed but Enhanced T Cell Immune Responses

2001 • 187 citations

Differential Susceptibility of Heart, Skin, and Islet Allografts to T Cell-Mediated Rejection

2001 • 172 citations

Activation of Peroxisome Proliferator-Activated Receptor-γ in Dendritic Cells Inhibits the Development of Eosinophilic Airway Inflammation in a Mouse Model of Asthma

2004 • 167 citations

Targeted deletion of CX3CR1 reveals a role for fractalkine in cardiac allograft rejection

2001 • 167 citations

Secondary Lymphoid Tissue Chemokine (CCL21) Activates CXCR3 to Trigger a Cl− Current and Chemotaxis in Murine Microglia

2002 • 150 citations

Chemokines and their receptors as markers of allograft rejection and targets for immunosuppression

2003 • 131 citations

Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease

2005 • 127 citations

Blocking the Monocyte Chemoattractant Protein-1/CCR2 Chemokine Pathway Induces Permanent Survival of Islet Allografts through a Programmed Death-1 Ligand-1-Dependent Mechanism

2003 • 108 citations

Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines

2005 • 107 citations

Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3β/mCCL19: comparison to human CCX-CKR

2002 • 97 citations

Modulation of experimental autoimmune encephalomyelitis: effect of altered peptide ligand on chemokine and chemokine receptor expression

2000 • 94 citations

Angiotensin II (AT1) Receptor Blockade Reduces Vascular Tissue Factor in Angiotensin II-Induced Cardiac Vasculopathy

2000 • 94 citations

Chemokine mediated control of dendritic cell migration and function

2003 • 84 citations

Targeting T cell responses by selective chemokine receptor expression

2003 • 80 citations

Post-translational control of chemokines: a role for decoy receptors?

2004 • 80 citations

Chemokine regulation of naı̈ve T cell traffic in health and disease

2003 • 80 citations

TRAFFICKING OF HOST- AND DONOR-DERIVED DENDRITIC CELLS IN RAT CARDIAC TRANSPLANTATION: ALLOSENSITIZATION IN THE SPLEEN AND HEPATIC NODES1

2001 • 76 citations

Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking

2005 • 75 citations

Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipients

2003 • 74 citations

Evidence of Functional Impairment of Syngeneically Transplanted Mouse Pancreatic Islets Retrieved from the Liver

2004 • 63 citations

The chemokine receptor CCR7 controls lymph node‐dependent cytotoxic T cell priming in alloimmune responses

2004 • 60 citations

PROLONGATION OF ALLOGRAFT SURVIVAL IN CCR7-DEFICIENT MICE

2004 • 42 citations

Enforced c-REL deficiency prolongs survival of islet allografts1

2002 • 33 citations

NEW DRUGS TO IMPROVE TRANSPLANT OUTCOMES

2004 • 31 citations

CXCL9 Antagonism Further Extends Prolonged Cardiac Allograft Survival in CCL19/CCL21‐Deficient Mice

2005 • 20 citations

Survival of Cardiac Xenografts

1975 • 15 citations

Promoting islet cell function after transplantation

2004 • 12 citations

D6 as a Decoy and Scavenger Receptor for Inflammatory CC Chemokines in the Skin

2006 • 1 citations