T-Cell Responses duringTrypanosoma bruceiInfections in Mice Deficient in Inducible Nitric Oxide Synthase

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Altered immune responses in mice lacking inducible nitric oxide synthase

1995 • 1,296 citations

The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up-regulated neuronal nitric oxide synthase.

1995 • 256 citations

Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins.

1993 • 249 citations

Nitric oxide-mediated cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei

1992 • 150 citations

CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule

1993 • 142 citations

High frequency of antigenic variation inTrypanosoma brucei rhodesienseinfections

1989 • 136 citations

Nitric oxide mediates suppression of T cell responses in murine Trypanosoma brucei infection

1992 • 136 citations

Septic Arthritis Following Staphylococcus aureus Infection in Mice Lacking Inducible Nitric Oxide Synthase

1998 • 106 citations

Characterization of T helper cell responses to the trypanosome variant surface glycoprotein.

1993 • 104 citations

Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase

1997 • 97 citations

Depletion of CD8+ T cells suppresses growth of Trypanosoma brucei brucei and interferon-gamma) production in infected rats

1990 • 86 citations

Macrophages as Mediators of Immunosuppression in Murine African Trypanosomiasis

1985 • 79 citations

Bone marrow nitric oxide production and development of anemia in Trypanosoma brucei-infected mice

1995 • 76 citations

IFN-γ-Dependent Nitric Oxide Production Is Not Linked to Resistance in Experimental African Trypanosomiasis

1999 • 71 citations

Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection

1994 • 68 citations

Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo

1995 • 64 citations

Trypanosoma brucei: Morphometric changes and loss of infectivity during transformation of bloodstream forms to procyclic culture forms in vitro

1979 • 61 citations

The role of the macrophage in induction of immunosuppression in Trypanosoma congolense-infected cattle.

1991 • 59 citations

Dual role of macrophages in the suppression of interleukin 2 production and interleukin 2 receptor expression in trypanosome‐infected mice

1989 • 54 citations

Inhibition of T-cell responsiveness during experimental infections with Trypanosoma brucei: active involvement of endogenous gamma interferon

1993 • 52 citations

Trypanosoma brucei is protected from the cytostatic effects of nitric oxide under in vivo conditions

1994 • 48 citations

Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse‐transmitted trypanosomiasis in cattle

1992 • 47 citations

Immunobiology of African Trypanosomiasis

1998 • 45 citations

Nitric oxide synthesis is depressed in Bos indicus cattle infected with Trypanosoma congolense and Trypanosoma vivax and does not mediate T-cell suppression

1996 • 44 citations

Commentary Antigenic variation in Trypanosoma brucei infections: an holistic view

1999 • 43 citations

Production of interferons during experimental African trypanosomiasis.

1983 • 43 citations

Suppressive macrophages occurring in murine Trypanosoma brucei infection inhibit T‐cell responses in vivo and in vitro

1990 • 42 citations

In vitro simulation of immunosuppression caused by Trypanosoma brucei.

1991 • 23 citations

Inhibition of growth of trypanosoma brucei parasites in chronic infections

1996 • 22 citations

Nitric oxide production in vervet monkeys (Cercopithecus aethiops) infected with Trypanosoma brucei

1998 • 21 citations

A comparison of multiplication rates in primary and challenge infections ofTrypanosoma bruceibloodstream forms

1990 • 13 citations