Photolysis of intracellular caged sphingosine‐1‐phosphate causes Ca²⁺ mobilization independently of G‐protein‐coupled receptors

The versatility and universality of calcium signalling

2000 • 5,407 citations

Sphingosine-1-phosphate: an enigmatic signalling lipid

2003 • 2,022 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

Sphingosine 1-Phosphate, a Key Cell Signaling Molecule

2002 • 551 citations

Lysophospholipids--Receptor Revelations

2001 • 539 citations

International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature

2002 • 462 citations

Role of the Sphingosine-1-Phosphate Receptor EDG-1 in PDGF-Induced Cell Motility

2001 • 421 citations

Calcium mobilization via sphingosine kinase in signalling by the FcɛRI antigen receptor

1996 • 374 citations

Lysophospholipid Receptors

2001 • 319 citations

Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors

2002 • 309 citations

Extracellular Export of Sphingosine Kinase-1 Enzyme

2002 • 281 citations

Signaling and biological actions of sphingosine 1-phosphate

2003 • 272 citations

Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium.

1994 • 253 citations

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

1998 • 208 citations

Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors

2002 • 201 citations

Activation of a High Affinity Gi Protein-coupled Plasma Membrane Receptor by Sphingosine-1-phosphate

1996 • 197 citations

Sphingosine‐1‐phosphate: dual messenger functions

2002 • 188 citations

FcγRI Coupling to Phospholipase D Initiates Sphingosine Kinase-mediated Calcium Mobilization and Vesicular Trafficking

1998 • 172 citations

EDG‐1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration

2001 • 167 citations

Dichotomy of Ca2+ Signals Triggered by Different Phospholipid Pathways in Antigen Stimulation of Human Mast Cells

2002 • 164 citations

Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate

2000 • 155 citations

Sphingosine kinase: a mediator of vital cellular functions

2001 • 151 citations

Sphingosine 1-phosphate signaling: providing cells with a sense of direction

2002 • 136 citations

Sphingosine 1-Phosphate, a Diffusible Calcium Influx Factor Mediating Store-operated Calcium Entry

2003 • 110 citations

Formyl Peptide Receptor Signaling in HL-60 Cells through Sphingosine Kinase

1999 • 99 citations

Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors

2001 • 95 citations

Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors

2002 • 87 citations

Lysophosphatidic Acid-induced Ca2+ Mobilization Requires Intracellular Sphingosine 1-Phosphate Production

2000 • 71 citations

Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63

2003 • 68 citations

Characterization of a novel intracellular sphingolipid-gated Ca(2+)-permeable channel from rat basophilic leukemia cells.

1994 • 66 citations

RyR1 and RyR3 isoforms provide distinct intracellular Ca2+signals in HEK 293 cells

2002 • 64 citations

N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors.

1996 • 57 citations

Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells

1993 • 57 citations

Depolarisation induces rapid and transient formation of intracellular sphingosine‐1‐phosphate

2001 • 42 citations

Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate—caged SPP

1998 • 41 citations

Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+release

2001 • 33 citations

Re-evaluation of primary structure, topology, and localization of Scamper, a putative intracellular Ca2+ channel activated by sphingosylphosphocholine

2002 • 32 citations

Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes

2003 • 25 citations

Re-evaluation of primary structure, topology, and localization of Scamper, a putative intracellular Ca2+ channel activated by sphingosylphosphocholine

2002 • 16 citations

Deleted Work

1955 • 0 citations