Local Intramural Delivery of <scp>l</scp> -Arginine Enhances Nitric Oxide Generation and Inhibits Lesion Formation After Balloon Angioplasty

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease

1994 • 4,561 citations

A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease

1994 • 4,260 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA registry of the national heart, lung, and blood institute

1984 • 1,122 citations

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.

1990 • 1,020 citations

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.

1992 • 822 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.

1995 • 783 citations

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

1992 • 749 citations

Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

1995 • 707 citations

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit.

1992 • 697 citations

A paradigm for restenosis based on cell biology: Clues for the development of new preventive therapies

1991 • 557 citations

Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits.

1986 • 535 citations

Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits.

1994 • 501 citations

Nitric Oxide Modulates the Expression of Monocyte Chemoattractant Protein 1 in Cultured Human Endothelial Cells

1995 • 475 citations

Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

1993 • 459 citations

The relative importance of arterial remodeling compared with intimal hyperplasia in lumen renarrowing after balloon angioplasty. A study in the normal rabbit and the hypercholesterolemic Yucatan micropig.

1994 • 418 citations

Heparin-Coated Palmaz-Schatz Stents in Human Coronary Arteries

1996 • 404 citations

Gene therapy inhibiting neointimal vascular lesion

1995 • 387 citations

Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis.

1989 • 357 citations

Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.

1991 • 340 citations

Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine.

1994 • 330 citations

Differences in compensatory vessel enlargement, not intimal formation, account for restenosis after angioplasty in the hypercholesterolemic rabbit model.

1994 • 317 citations

L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.

1990 • 278 citations

Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury.

1990 • 256 citations

Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.

1994 • 255 citations

N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.

1989 • 245 citations

Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury.

1994 • 245 citations

L-Arginine Inhibits Balloon Catheter-Induced Intimal Hyperplasia

1993 • 223 citations

<scp>l</scp> -Arginine Induces Nitric Oxide–Dependent Vasodilation in Patients With Critical Limb Ischemia

1996 • 185 citations

Exposure to Shear Stress Alters Endothelial Adhesiveness

1995 • 181 citations

Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery.

1990 • 175 citations

Molecular Therapies for Vascular Diseases

1996 • 173 citations

Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty.

1994 • 144 citations

Effect of L-arginine on coronary endothelial function in cardiac transplant recipients. Relation to vessel wall morphology.

1994 • 136 citations

Long-term oral administration of L-arginine reduces intimal thickening and enhances neoendothelium-dependent acetylcholine-induced relaxation after arterial injury.

1994 • 133 citations

Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit

1994 • 123 citations

A new approach for local intravascular drug delivery. Iontophoretic balloon.

1994 • 75 citations

Intramural methotrexate therapy for the prevention of neointimal thickening after ballon angioplasty

1992 • 73 citations

Human monocyte characteristics are altered in hypercholesterolaemia

1991 • 46 citations

Reduced prostacyclin formation after reoxygenation of anoxic endothelium

1990 • 37 citations

Use of the porous balloon in porcine coronary arteries: rationale for low pressure and volume delivery

1993 • 19 citations