<scp>l</scp> -Arginine Induces Nitric Oxide–Dependent Vasodilation in Patients With Critical Limb Ischemia

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.

1990 • 1,020 citations

Crucial role of endothelium in the vasodilator response to increased flow in vivo.

1986 • 991 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.

1992 • 822 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Cyclic guanosine monophosphate as a mediator of vasodilation.

1986 • 811 citations

Measurement of blood flow by ultrasound: Accuracy and sources of error

1985 • 766 citations

Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis

1992 • 471 citations

Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.

1988 • 422 citations

Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans.

1989 • 421 citations

Metabolism and excretion of nitric oxide in humans. An experimental and clinical study.

1993 • 404 citations

Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta.

1991 • 340 citations

L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.

1990 • 278 citations

Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production

1995 • 251 citations

Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses

1990 • 250 citations

<scp>l</scp>-Arginine Infusion Decreases Peripheral Arterial Resistance and Inhibits Platelet Aggregation in Healthy Subjects

1994 • 151 citations

L-Arginine is a precursor for nitrate biosynthesis in humans

1989 • 133 citations

<scp>l</scp>‐ARGININE INFUSION INDUCES HYPOTENSION AND DIURESIS/NATRIURESIS WITH CONCOMITANT INCREASED URINARY EXCRETION OF NITRITE/NITRATE AND CYCLIC GMP IN HUMANS

1992 • 128 citations

Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography—mass spectrometry using their 15N-labelled analogs

1994 • 124 citations

Increase of an endogenous inhibitor of nitric oxide synthesis in serum of high cholesterol fed rabbits

1994 • 116 citations

Exercise Increases Systemic Nitric Oxide Production in Men

1994 • 96 citations

Mechanisms of Abnormal Endothelium-Dependent Vascular Relaxation in Atherosclerosis: Implications for Altered Autocrine and Paracrine Functions of EDRF

1989 • 92 citations

Investigation of decreased availability of nitric oxide precursor as the mechanism responsible for impaired endothelium-dependent vasodilation in hypercholesterolemic patients

1994 • 79 citations

Long term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats

1994 • 76 citations

Alteration in prostacyclin and prostaglandin E2 production. Correlation with changes in human aortic atherosclerotic disease.

1984 • 69 citations

Effects of low-dose aspirin on endogenous eicosanoid formation in normal and atherosclerotic men

1988 • 47 citations

Determination of endothelium-derived nitrite/nitrate by gas chromatography/tandem mass spectrometry using (15N)NaNO2 as internal standard

1992 • 34 citations

The measurement of arginine in plasma

1971 • 19 citations

Effects of intra‐arterial prostaglandin E₁ in patients with peripheral arterial occlusive disease

1986 • 19 citations

Hemodynamic Effects of Intravenous PGE1 on Patients with Arterial Occlusive Disease of the Leg

1985 • 16 citations

Intermittent intra-arterial prostaglandin E1 therapy of severe claudication.

1987 • 14 citations