Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

1993 • 1,646 citations

Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.

1995 • 1,271 citations

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 • 1,147 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1992 • 780 citations

How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture.

1986 • 744 citations

Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.

1997 • 415 citations

IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor.

1993 • 411 citations

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice.

1996 • 405 citations

Interleukin-8. A corneal factor that induces neovascularization.

1992 • 385 citations

The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis.

1997 • 380 citations

Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.

1994 • 373 citations

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice.

1994 • 357 citations

Expression of interleukin-8 correlates with vascularity in human gastric carcinomas.

1998 • 262 citations

Role of C-X-C chemokines as regulators of angiogenesis in lung cancer

1995 • 250 citations

Role of Growth Factors, Cytokines, and Their Receptors in the Pathogenesis of Psoriasis

1990 • 248 citations

Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer.

1996 • 243 citations

Demonstration and characterization of the angiogenic properties of cervical dysplasia.

1994 • 234 citations

Extent of vascularization as a prognostic indicator in thin (< 0.76 mm) malignant melanomas.

1994 • 230 citations

Identification of C5ades arg and an Anionic Neutrophil-Activating Peptide (ANAP) in Psoriatic Scales

1986 • 230 citations

Interleukin-8 and MCAF: Novel Leukocyte Recruitment and Activating Cytokines

2015 • 210 citations

Extent of tumor vascularization correlates with prognosis and hematogenous metastasis in gastric carcinomas.

1996 • 200 citations

Growth factors and oncogenes in human gastrointestinal carcinomas

1990 • 185 citations

Induction of haptotactic migration of melanoma cells by neutrophil activating protein/interleukin-8

1990 • 175 citations

Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1.

1985 • 170 citations

Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique.

1997 • 155 citations

Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system.

1992 • 152 citations

Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas.

1998 • 145 citations

Expression of interleukin-8 receptors on tumor cells and vascular endothelial cells in human breast cancer tissue.

1998 • 141 citations

Induction of Cytokines in Human Peripheral Blood Mononuclear Cells by Mycoplasmas

1992 • 119 citations

Regulation of interleukin-8 expression in human melanoma cells by the organ environment.

1995 • 115 citations

Coexpression of interleukin-8 receptors in head and neck squamous cell carcinoma

1997 • 101 citations

Interleukin 1 alpha acts as an autocrine growth stimulator for human gastric carcinoma cells.

1993 • 85 citations

Expression of vascular endothelial growth factor in human gastric carcinomas

1998 • 70 citations

Expression of basic fibroblast growth factor in human gastric carcinomas

1992 • 69 citations

Enhancement of murine tumor cell sensitivity to adriamycin by presentation of the drug in phosphatidylcholine-phosphatidylserine liposomes.

1990 • 60 citations

Amplification and rearrangement of the Kirsten ras oncogene in virus-transformed BALB/c 3T3 cells during malignant tumor progression.

1987 • 58 citations

Constitutive production of multiple cytokines and a human chorionic gonadotrophin beta-subunit by a human bladder cancer cell line (KU-19-19): possible demonstration of totipotential differentiation

1997 • 48 citations

Expression of Interleukin-6 and Its Effect on the Cell Growth of Gastric Carcinoma Cell Lines

1997 • 38 citations

Interleukin-1 induced gene expression of neutrophil activating protein (interleukin-8) and monocyte chemotactic peptide in human synovial cells

1991 • 38 citations