Polyclonal expansion of adoptively transferred CD4⁺ αβ T cells in the colonic lamina propria of scid mice with colitis

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

Inflammatory Bowel Disease

1991 • 1,264 citations

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

1994 • 1,129 citations

Phenotypically distinct subsets of CD4⁺ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1993 • 1,064 citations

The SCID Mouse Mutant: Definition, Characterization, and Potential Uses

1991 • 743 citations

Handbook of Mucosal Immunology

1994 • 711 citations

Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

1994 • 630 citations

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.

1994 • 625 citations

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells.

1993 • 471 citations

Expression and regulation of β₇(βp) integrins on mouse lymphocytes: Relevance to the mucosal immune system

1991 • 222 citations

Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice

1993 • 193 citations

T cell differentiation antigens on lymphocytes in the human intestinal lamina propria.

1992 • 165 citations

Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine.

1993 • 164 citations

The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex.

1994 • 135 citations

Expression of homing and adhesion molecules in infiltrated islets of Langerhans and salivary glands of nonobese diabetic mice.

1994 • 121 citations

T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine

1993 • 100 citations

Transforming growth factor‐β₁‐induced expression of the mucosa‐related integrin α_E on lymphocytes is not associated with mucosa‐specific homing

1995 • 97 citations

Regional Specialization of Intraepithelial T Cells in the Murine Small and Large Intestine

1995 • 79 citations

Characterization of an Early Activation‐Dependent Antigen on Lymphocytes Defined by the Monoclonal Antibody BL‐Ac(F2)

1994 • 75 citations

Structure of the gene coding for the human early lymphocyte activation antigen CD69: A C‐type lectin receptor evolutionarily related with the gene families of natural killer cell‐specific receptors

1994 • 60 citations

Epithelial Proliferation in Response to Gastrointestinal Inflammation

1992 • 55 citations

Co-expression of CD8α in CD4+ T cell receptor αβ+ T cells migrating into the murine small intestine epithelial layer

1995 • 53 citations

Antigen-specific and polyclonal CD4+ lamina propria T-cell lines: phenotypic and functional characterization.

1992 • 51 citations

Activation of mucosal Vβ3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B

1993 • 48 citations

Gut‐homing CD4⁺ T cell receptor αβ⁺ T cells in the pathogenesis of murine inflammatory bowel disease

1994 • 44 citations

Heterogeneity and biased T cell receptor alpha/beta repertoire of mucosal CD8+ cells from murine large intestine: implications for functional state.

1994 • 42 citations

Activation of lamina propria T cells induces crypt epithelial proliferation and goblet cell depletion in cultured human fetal colon.

1992 • 40 citations

T Helper Cells for Mucosal Immune Responses

1994 • 39 citations

Human Gastrointestinal Mucosal T Cells

1994 • 37 citations

Selective Reconstitution of T Lymphocyte Subsets in scid Mice

1991 • 36 citations

CD3⁺ T cells in severe combined immunodeficiency (scid) mice. II. Transplantation of dm2 lymphoid cells into semi‐allogeneic scid mice

1991 • 32 citations

CD3⁺ T cells in severe combined immune deficiency (scid) mice. I. Transferred purified CD4⁺ T cells, but not CD8⁺ T cells are engrafted in the spleen of congenic scid mice

1991 • 31 citations

Lamina Propria T Cell Subsets in the Small and Large Intestine of Euthymic and Athymic Mice

1995 • 23 citations

Novel experimental approaches in the study of the immunopathology in inflammatory bowel disease

1995 • 22 citations

CD3⁺ T-cells in severe combined immunodeficiency (scid) mice III. Transferred congenic, selfreactive CD4⁺T cell clones rescue IgM-producing, Scid-derived B cells

1991 • 22 citations

Selective engraftment of memory CD4⁺ T cells with an unusual recirculation pattern and a diverse T cell receptor‐Vβ repertoire into scid mice

1993 • 21 citations

Animal models of inflammatory bowel disease

1993 • 19 citations

New models of chronic intestinal inflammation

1994 • 18 citations

A gut‐homing, oligoclonal CD4⁺ T cell population in severe‐combined immunodeficient mice expressing a rearranged, transgenic class I‐restricted αβ T cell receptor

1995 • 18 citations

T cell specialization at environmental interfaces: T cells from the lung and the female genital tract of lpr and gld mice differ from their splenic and lymph node counterparts

1994 • 15 citations

Reconstitution of SCID mice with low numbers of CD4+ TCRαβ+ T cells

1994 • 14 citations

CD3+ T cells in severe combined immunodeficiency (scid) mice. VI. Rescue of scid-derived, IgM-producing B cells by transfer of CD4+ CD8- T cells from various lymphoid organs.

1992 • 13 citations

Transplantation of CD4+ T cell clones into SCID mice

1993 • 11 citations

Genetically engineered models of inflammatory bowel disease

1994 • 11 citations

Commentary

1994 • 4 citations