CD3+ T cells in severe combined immune deficiency (scid) mice. I. Transferred purified CD4+ T cells, but not CD8+ T cells are engrafted in the spleen of congenic scid mice

Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease.

1985 • 721 citations

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

1986 • 558 citations

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

1989 • 351 citations

Evidence of functional lymphocytes in some (leaky) scid mice.

1988 • 347 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis.

1982 • 321 citations

Genetic susceptibility to post-thymectomy autoimmune diseases in mice

1981 • 265 citations

Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences.

1986 • 229 citations

Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer.

1982 • 217 citations

Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease.

1989 • 197 citations

Manipulation of T-Cell Responses with Monoclonal Antibodies

1989 • 196 citations

The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells.

1987 • 173 citations

Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance.

1987 • 166 citations

Experimental autoimmune prostatitis after neonatal thymectomy in the mouse.

1985 • 161 citations

Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens.

1985 • 137 citations

Autoimmune oophoritis in thymectomized mice: detection of circulating antibodies against oocytes.

1980 • 125 citations

Analysis of T-cell subsets in rejection of Kb mutant skin allografts differing at class I MHC

1986 • 114 citations

Population dynamics of T lymphocytes. Renewal rate and expansion in the peripheral lymphoid organs.

1983 • 113 citations

T cell repopulation from functionally restricted splenic progenitors: 10,000-fold expansion documented by using limiting dilution analyses.

1984 • 105 citations

Occurrence of mature B (IgM+, B220+) and T (CD3+) lymphocytes in scid mice.

1989 • 102 citations

Autoimmune oophoritis in thymectomized mice: T cell requirement in adoptive cell transfer.

1980 • 95 citations

Lyt-2- T cell-independent functions of Lyt-2+ cells stimulated with antigen or concanavalin A.

1984 • 59 citations

Development of multiple organ-localized autoimmune diseases in nude mice after reconstitution of T cell function by rat fetal thymus graft.

1986 • 58 citations

Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia− tumour cells

1986 • 56 citations

Cytotoxic T cells both produce and respond to interleukin 2

1984 • 55 citations

Population kinetics of precursors of IL 2-producing peripheral T lymphocytes: evidence for short life expectancy, continuous renewal, and post-thymic expansion.

1987 • 53 citations

Detection and characterization of functional T cells in mice with severe combined immune deficiency

1988 • 52 citations

T-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.

1990 • 46 citations

Autonomously proliferating K/D‐restricted cytolytic T cell clones

1983 • 44 citations

The scid Mutation: Occurrence and Effect

1989 • 43 citations

Development of autoreactive L3T4⁺ T cells from double‐negative (L3T4⁻/Ly‐2⁻) Thy‐1⁺ spleen cells of normal mice

1988 • 37 citations

T Cell Leakiness in Scid Mice

1989 • 32 citations

L3T4 effector cells in multiple organ-localized autoimmune disease in nude mice grafted with embryonic rat thymus.

1988 • 25 citations

Limited Clonal Diversity of Serum Immunoglobulin in Leaky Scid Mice

1989 • 24 citations

Induction of TNP-specific cytotoxic T lymphocyte memory in vivo in the absence of T helper cell activity.

1986 • 10 citations

Pauciclonal B Cell Involvement in Production of Immunoglobulin in Scid Ig+ Mice

1989 • 7 citations

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