Pulmonary cachexia, systemic inflammatory profile, and the interleukin 1β −511 single nucleotide polymorphism

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

2012 • 16,041 citations

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

2001 • 6,099 citations

Assessment of fat-free mass using bioelectrical impedance measurements of the human body

1985 • 1,873 citations

Invited Review: Aging and sarcopenia

2003 • 1,757 citations

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

2004 • 1,754 citations

Systemic effects of chronic obstructive pulmonary disease

2003 • 1,024 citations

Midthigh Muscle Cross-Sectional Area Is a Better Predictor of Mortality than Body Mass Index in Patients with Chronic Obstructive Pulmonary Disease

2002 • 821 citations

Prevalence and Characteristics of Nutritional Depletion in Patients with Stable COPD Eligible for Pulmonary Rehabilitation

1993 • 730 citations

Cytokines in chronic obstructive pulmonary disease

2001 • 607 citations

Presence of the IL‐1RA Allele 2 (IL1RN*2) is Associated with Enhanced IL‐1β Production In Vitro

1998 • 543 citations

Cachexia

2000 • 378 citations

Inflammatory Response and Body Composition in Chronic Obstructive Pulmonary Disease

2001 • 377 citations

Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD

1994 • 371 citations

Elevated TNF-alpha production by peripheral blood monocytes of weight-losing COPD patients.

1996 • 342 citations

Associated Loss of Fat-free Mass and Bone Mineral Density in Chronic Obstructive Pulmonary Disease

2004 • 339 citations

S<scp>ARCOPENIA</scp>, W<scp>EIGHT</scp> L<scp>OSS</scp>, <scp>AND</scp> N<scp>UTRITIONAL</scp> F<scp>RAILTY IN THE</scp> E<scp>LDERLY</scp>

2002 • 330 citations

Tissue depletion and health related quality of life in patients with chronic obstructive pulmonary disease

2000 • 330 citations

Susceptibility Genes for Rapid Decline of Lung Function in the Lung Health Study

2001 • 268 citations

Genotyping for polymorphisms in interferon-γ, interleukin-10, transforming growth factor-β1 and tumour necrosis factor-α genes: a technical report

1998 • 266 citations

Body composition by bioelectrical-impedance analysis compared with deuterium dilution and skinfold anthropometry in patients with chronic obstructive pulmonary disease

1991 • 251 citations

Catabolic/Anabolic Balance and Muscle Wasting in Patients With COPD

2003 • 238 citations

Geriatric cachexia: the role of cytokines

1999 • 220 citations

Body composition and health-related quality of life in patients with obstructive airways disease

1997 • 202 citations

The Diffusing Capacity as a Predictor of Arterial Oxygen Desaturation during Exercise in Patients with Chronic Obstructive Pulmonary Disease

1984 • 178 citations

Polyunsaturated fatty acids improve exercise capacity in chronic obstructive pulmonary disease

2005 • 174 citations

Leptin and Soluble Leptin Receptor Levels in Obese and Weight-Losing Individuals

2002 • 165 citations

Slow release of soluble TNF receptors by monocytes in vitro.

1994 • 150 citations

IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease

1999 • 142 citations

Rapid Inhibition ofobGene Expression and Circulating Leptin Levels in Lean Mice by the β3-Adrenoceptor Agonists BRL 35135A and ZD2079

1996 • 116 citations

Enhanced Levels of Whole-body Protein Turnover in Patients with Chronic Obstructive Pulmonary Disease

2000 • 114 citations

A Polymorphism in the Tumor Necrosis Factor-α Gene Promoter Region May Predispose to a Poor Prognosis in COPD

2000 • 108 citations

Hypothalamic-pituitary dysfunction in respiratory hypoxia.

1981 • 107 citations

A Novel Pathophysiologic Phenomenon in Cachexic Patients with Chronic Obstructive Pulmonary Disease

2001 • 98 citations

Tumour necrosis factor-α gene promoter polymorphism in chronic obstructive pulmonary disease

2000 • 94 citations

Inappropriately low plasma leptin concentration in the cachexia associated with chronic heart failure

1999 • 91 citations

Association of IL-1beta and IL-1 receptor antagonist haplotypes with rate of decline in lung function in smokers

2001 • 91 citations

Neither IL-1 β, IL-1 receptor antagonist, nor TNF- α polymorphisms are associated with susceptibility to COPD

2000 • 84 citations

Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma

2003 • 75 citations

Genetic polymorphisms of the interleukin‐1 gene and early marginal bone loss around endosseous dental implants

2003 • 74 citations

Objetivos para el tratamiento del asma: ¿hasta dónde se debería llegar?

2005 • 71 citations

Pulmonary cachexia

2002 • 70 citations

Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease

2002 • 69 citations

Tumor Necrosis Factor Gene Complex in COPD and Disseminated Bronchiectasis

2000 • 60 citations

Polymorphisms of TNFα, IL1β, and IL1RN genes in chronic obstructive pulmonary disease

2005 • 48 citations

Genomic interactions with disease and nutrition

2003 • 38 citations

Influence of TNFα and LTα single nucleotide polymorphisms on susceptibility to and prognosis in cutaneous malignant melanoma in the British population

2002 • 38 citations

Interleukin-1 beta primes interleukin-8-stimulated chemotaxis and elastase release in human neutrophils via its type I receptor.

1997 • 27 citations

Evaluation of two new high-sensitivity methods for C-reactive protein

2003 • 20 citations

Simultaneous determination of pseudouridine and creatinine in urine of normal children and patients with leukaemia by high performance liquid chromatography

1992 • 18 citations