Early Life Stress Changes Concentrations of Neuropeptide Y and Corticotropin-releasing Hormone in Adult Rat Brain. Lithium Treatment Modifies These Changes

Mammalian Neural Stem Cells

2000 • 4,689 citations

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress

1997 • 3,131 citations

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

The Corticosteroid Receptor Hypothesis of Depression

2000 • 2,126 citations

Hippocampal atrophy in recurrent major depression.

1996 • 1,884 citations

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

1993 • 1,626 citations

The role of corticotropin-releasing factor in depression and anxiety disorders

1999 • 1,371 citations

Adult brain neurogenesis and psychiatry: a novel theory of depression

2000 • 936 citations

Clinical Characteristics of Women With a History of Childhood Abuse

1997 • 915 citations

Adrenal hormones suppress cell division in the adult rat dentate gyrus

1992 • 638 citations

Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia

1999 • 570 citations

PROPHYLACTIC LITHIUM: DOUBLE BLIND DISCONTINUATION IN MANIC-DEPRESSIVE AND RECURRENT-DEPRESSIVE DISORDERS

1970 • 500 citations

Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation.

1996 • 493 citations

Ethanol consumption and resistance are inversely related to neuropeptide Y levels

1998 • 477 citations

Neonatal Handling Alters Adrenocortical Negative Feedback Sensitivity and Hippocampal Type II Glucocorticoid Receptor Binding in the Rat

1989 • 470 citations

Childhood Parental Loss and Adult Psychopathology in Women

1992 • 401 citations

Neuropeptide Y functions as a neuroproliferative factor

2001 • 338 citations

Corticotropin-releasing factor and neuropeptide y: role in emotional integration

1994 • 320 citations

Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression

2000 • 306 citations

Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat

1987 • 285 citations

Hypophysial-Portal Plasma Levels, Median Eminence Content, and Immunohistochemical Staining of Corticotropin-Releasing Factor, Arginine Vasopressin, and Oxytocin after Pharmacological Adrenalectomy*

1987 • 249 citations

Neuropeptide Y, epinephrine and norepinephrine in the paraventricular nucleus: Stimulation of feeding and the release of corticosterone, vasopressin and glucose

1988 • 217 citations

Corticotropin-releasing factor in the paraventricular nucleus modulates feeding induced by neuropeptide Y

1993 • 209 citations

Periodic maternal separation of neonatal rats produces region- and gender-specific effects on biogenic amine content in postmortem adult brain

2001 • 200 citations

Neuropeptide Y Levels in Ethanol‐Naive Alcohol‐Preferring and Nonpreferring Rats and in Wistar Rats after Ethanol Exposure

1998 • 189 citations

Neonatal Maternally Deprived Rats have as Adults Elevated Basal Pituitary‐Adrenal Activity and Enhanced Susceptibility to Apomorphine

1996 • 185 citations

Neuropeptide-Y and ACTH-immunoreactive innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamus of the rat

1988 • 181 citations

Neuropeptide-Y exerts antidepressant-like effects in the forced swim test in rats

2000 • 142 citations

Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism

1992 • 140 citations

Neuropeptide Y increases the corticotropin-releasing factor messenger ribonucleic acid level in the rat hypothalamus

1993 • 136 citations

Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation

1996 • 126 citations

Neuropeptide y administration acutely increases hypothalamic corticotropin-releasing factor immunoreactivity: Lack of effect in other rat brain regions

1987 • 124 citations

Increased catecholamine levels in specific brain regions of a rat model of depression: normalization by chronic antidepressant treatment

1999 • 123 citations

Involvement of hippocampal neuropeptide Y in mediating the chronic actions of lithium, electroconvulsive stimulation and citalopram

2000 • 116 citations

Alterations of corticotropin releasing hormone (CRH) and neuropeptide Y (NPY) plasma levels in mood disorder patients with a recent suicide attempt

1999 • 115 citations

Early maternal separation alters neuropeptide Y concentrations in selected brain regions in adult rats

2001 • 99 citations

Effect of repeated electroconvulsive treatment on regional concentrations of tachykinins, neurotensin, vasoactive intestinal polypeptide, neuropeptide Y, and galanin in rat brain

1989 • 96 citations

Early maternal deprivation alters hippocampal levels of neuropeptide Y and calcitonin-gene related peptide in adult rats

2002 • 93 citations

CRF/NPY interactions: A potential role in sleep dysregulation in depression and anxiety

1997 • 92 citations

Neuropeptide Y in male and female brains of flinders sensitive line, a rat model of depression. Effects of electroconvulsive stimuli

2000 • 89 citations

Neuropeptides and Electroconvulsive Treatment

1999 • 83 citations

Neuropeptide Y, neurokinin A and neurotensin in brain regions of Fawn Hooded “depressed”, wistar, and Sprague dawley rats. Effects of electroconvulsive stimuli

1998 • 82 citations

Neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons

1990 • 81 citations

Chronic Administration of Glucocorticoids Directly Upregulates Prepro‐Neuropeptide Y and Y₁‐Receptor mRNA Levels in the Arcuate Nucleus of the Rat

1994 • 81 citations

The Relation of Childhood Separation Experiences to Adult Depressive and Anxiety States

1982 • 79 citations

Differential Regulation of Neuropeptide Y mRNA Expression in the Arcuate Nucleus and Locus Coeruleus by Stress and Antidepressants

2000 • 77 citations

Dexamethasone treatment increases neuropeptide Y levels in rat hypothalamic neurones

1988 • 74 citations

Neuropeptide-Y stimulates CRF-41 release from rat hypothalami in vitro

1989 • 67 citations

Limbic effects of repeated electroconvulsive stimulation on neuropeptide Y and somatostatin mRNA expression in the rat brain

1995 • 60 citations

The effect of amphetamine on the in vivo release of dopamine, somatostatin and neuropeptide Y from rat caudate nucleus

1987 • 59 citations

Neuropeptide Y in the hypothalamus: effect on corticosterone and single-unit activity

1990 • 54 citations

Effects of olfactory bulbectomy on neuropeptide gene expression in the rat olfactory/limbic system

1998 • 53 citations

Changed Concentrations of Tachykinins and Neuropeptide Y in Brain of a Rat Model of Depression Lithium Treatment Normalizes Tachykinins

2001 • 52 citations

Cerebrospinal fluid concentrations of neuropeptide Y in depressed patients and in controls.

1992 • 49 citations

Effects of electroconvulsive treatment on somatostattn, neuropeptide Y, endothelin, and neurokinin a concentrations in cerebrospinal fluid of depressed patients: A pilot study

1995 • 44 citations

Effects of electroconvulsive stimuli and MK-801 on neuropeptide Y, neurokinin A, and calcitonin gene-related peptide in rat brain.

1997 • 44 citations

Region-specific effects of chronic lithium administration on neuropeptide Y and somatostatin mRNA expression in the rat brain

1995 • 43 citations

Biological correlates of attachment bond disruption in humans and nonhuman primates

1984 • 42 citations

Comparison of a specific two-site immunoradiometric assay with radioimmunoassay for rat/human CRF-41

1986 • 41 citations

Chronic parenteral antidepressant treatment in rats: Unaltered levels and processing of neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH)

1995 • 38 citations

The effect of dexamethasone on neuropeptide y concentrations in specific hypothalamic regions

1992 • 32 citations

Effects of typical and atypical antipsychotics on neuropeptide Y in rat brain tissue and microdialysates from ventral striatum

2000 • 26 citations

Effects of putative cognitive function-enhancing drugs and dopaminergic agents on somatostatin and neuropeptide Y in rat brain

1993 • 17 citations

Effects of Psychotropic Medications on Hypothalamic-Pituitary-Adrenal Regulation

1988 • 14 citations

CRF/NPY interactions: A potential role in sleep dysregulation in depression and anxiety

1997 • 6 citations

Effect of lithium chloride on adrenocortical activity in male rats: evidence of dose and duration dependent response.

1990 • 5 citations

Neuropeptide Y Levels in Ethanol-Naive Alcohol-Preferring and Nonpreferring Rats and in Wistar Rats after Ethanol Exposure

1998 • 3 citations