Neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Distribution of substance P-like immunoreactivity in the central nervous system of the rat—I. Cell bodies and nerve terminals

1978 • 1,426 citations

Neuropeptide Y Distribution in the Rat Brain

1983 • 1,093 citations

Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor

1983 • 751 citations

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.

1986 • 744 citations

Different populations of GABAergic neurons in the visual cortex and hippocampus of cat contain somatostatin- or cholecystokinin- immunoreactive material

1984 • 733 citations

A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: Evidence from immunohistochemistry combined with retrograde tracing

1980 • 717 citations

Immunochemical evidence of cholecystokinin-like peptides in brain

1976 • 676 citations

Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A.

1987 • 651 citations

Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study

1988 • 649 citations

The Regional Distribution of Somatostatin in the Rat Brain

1975 • 594 citations

Complete coding sequence of rat tyrosine hydroxylase mRNA.

1985 • 544 citations

Tachykinins

1988 • 542 citations

Neuropeptide-containing neurons of the cerebral cortex are also GABAergic.

1984 • 537 citations

Cholecystokinin octapeptide-like immunoreactivity: histochemical localization in rat brain.

1979 • 444 citations

Regional distribution of substance P in the brain of the rat

1976 • 417 citations

Morphology, distribution, and synaptic relations of somatostatin- and neuropeptide Y-immunoreactive neurons in rat and monkey neocortex

1984 • 415 citations

Regional distribution of neurotensin and somatostatin in rat brain

1977 • 408 citations

Cloning and sequence analysis of a cDNA encoding rat preprocholecystokinin.

1984 • 355 citations

Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.

1988 • 318 citations

Structure and expression of the rat neuropeptide Y gene.

1987 • 300 citations

Distribution of somatostatin in the rat brain: Telencephalon and diencephalon

1980 • 279 citations

Somatostatin immunoreactive neurons in the human hippocampus and cortex shown by immunogold/silver intensification on vibratome sections: Coexistence with neuropeptide Y neurons, and effects alzheimer‐type dementia

1987 • 252 citations

Rat pre-prosomatostatin. Structure and processing by microsomal membranes.

1983 • 218 citations

In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes

1986 • 207 citations

Molecular structure of mammalian neuropeptide Y: analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue.

1987 • 203 citations

Coexistence of neuropeptide Y and somatostatin in rat and human cortical and rat hypothalamic neurons

1984 • 203 citations

Somatostatin regulates dopamine release in rat striatal slices and cat caudate nuclei

1983 • 203 citations

Cholecystokinin-immunoreactive neurons in rat and monkey cerebral cortex make symmetric synapses and have intimate associations with blood vessels.

1983 • 181 citations

Somatostatin and dementia in Parkinson's disease

1983 • 172 citations

Dopamine antagonist haloperidol decreases substance P, substance K, and preprotachykinin mRNAs in rat striatonigral neurons.

1986 • 161 citations

Brain neurotransmitter changes in Parkinson's disease

1981 • 157 citations

Cholecystokinin-like immunoreactive neurons in rat cerebral cortex

1983 • 152 citations

Immunohistochemical studies on cholecystokinin (CCK)-immunoreactive neurons in the rat using sequence specific antisera and with special reference to the caudate nucleus and primary sensory neurons.

1988 • 150 citations

Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains

1983 • 148 citations

Seven peptides derived from pro-somatostatin in rat brain

1982 • 146 citations

Neuropeptide coexistence in human cortical neurones

1982 • 140 citations

Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation

1989 • 139 citations

Regional distribution of neuromedin K and neuromedin L in rat brain and spinal cord

1984 • 136 citations

Origin of the Cholecystokinin-Containing Fibers in the Rat Caudatoputamen

1982 • 132 citations

Region specific regulation of glutamic acid decarboxylase mRNA expression by dopamine neurons in rat brain

1989 • 131 citations

Regional distribution of substance P, neurokinin α and neurokinin β in rat central nervous system

1984 • 128 citations

Striatal neuropeptide Y neurones are under the influence of the nigrostriatal dopaminergic pathway: Immunohistochemical evidence

1986 • 119 citations

Localization of neuropeptide Y messenger ribonucleic acid in rat and mouse brian by in situ hybridization

1987 • 115 citations

Concomitant increase of somatostatin, neuropeptide y and glutamate decar☐ylase in the frontal cortex of rats with decreased seizure threshold

1988 • 109 citations

Evidence that striatal efferents relate to different dopamine receptors

1984 • 107 citations

CCK-8-immunoreactivity distribution in human brain: selective decrease in the substantia nigra from parkinsonian patients

1982 • 106 citations

Immunohistochemical and in situ hybridization analysis of the development of the rat somatostatin‐containing neocortical neuronal system

1988 • 105 citations

Neuronal localization of prosomatostatin mRNA in the rat brain with in situ hybridization histochemistry

1988 • 95 citations

Pharmacological characterization of dopaminergic influence on expression of neuropeptide Y immunoreactivity by rat striatal neurons

1988 • 93 citations

Modulation of tyrosine hydroxylase gene expression in the central nervous system visualized by in situ hybridization.

1987 • 89 citations

Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity

1984 • 70 citations

Distribution of neuropeptide Y in the forebrain and diencephalon: an immunohistochemical analysis

1985 • 68 citations

Neuropeptide Y-immunoreactive neurons receive synaptic inputs from dopaminergic axon terminals in the rat neostriatum

1988 • 64 citations

The effect of neuropeptide Y on striatal catecholamines

1986 • 63 citations

The colocalization of cholecystokinin and tyrosine hydroxylase mRNAs in mesencephalic dopaminergic neurons in the rat brain examined byin situ hybridization

1989 • 62 citations

Striatal tachykinin gene expression regulated by interaction of D-1 and D-2 dopamine receptors.

1989 • 61 citations

Effects of lesions on somatostatin-like immunoreactivity in the rat striatum

1983 • 60 citations

Somatostatin mRNA: regional variation in hybridization densities in individual neurons

1986 • 58 citations

Regional distribution and in vivo release of tachykinin-like immunoreactivities in rat brain: evidence for regional differences in relative proportions of tachykinins

1985 • 57 citations

In situ hybridization of putative somatostatin mRNA within hypothalamus of the rat using synthetic oligonucleotide probes

1985 • 56 citations

Somatostatin Precursor in the Rat Striatum: Changes After Local Injection of Kainic Acid

1985 • 55 citations

Neuropeptides in Alzheimer's disease: a postmortem study

1989 • 53 citations

Involvement of the D-2 dopamine receptor in the neuroleptic-induced decrease in nigral substance P

1984 • 52 citations

Preprocholecystokinin mRNA in rat brain: regional expression includes thalamus

1988 • 51 citations

Opposite responses in the striato-nigral substance P system to D1 and D2 receptor activation

1984 • 47 citations

Regional distribution and regulation of preprosomatostatin messenger RNA in the striatum, as revealed by in situ hybridization histochemistry

1989 • 46 citations

Demonstration and Distribution of Kassinin‐Like Material (Substance K) in the Rat Central Nervous System

1985 • 44 citations

A comparison of regional somatostatin and neuropeptide Y distribution in rat striatum and brain

1986 • 43 citations

Long-term effects of cholinergic basal forebrain lesions on neuropeptide Y and somatostatin immunoreactivity in rat neocortex

1989 • 33 citations

Mesencephalic dopamine innervation of the frontoparietal (sensorimotor) cortex of the rat: A microdialysis study

1989 • 32 citations

Developmental and regional changes of cholecystokinin mRNA in rat brains

1986 • 26 citations

Somatostatin and neuropeptide Y immunoreactivity in parkinson's disease dementia with alzheimer's changes

1988 • 23 citations