Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

2013 • 8,227 citations

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Spatial localization does not require the presence of local cues

1981 • 2,665 citations

Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

1982 • 2,244 citations

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

1986 • 1,509 citations

What's Wrong with My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice

2000 • 934 citations

Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides

1993 • 528 citations

Ethanol consumption and resistance are inversely related to neuropeptide Y levels

1998 • 477 citations

Cloned human neuropeptide Y receptor couples to two different second messenger systems.

1992 • 430 citations

Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.

1992 • 429 citations

Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models

1989 • 378 citations

Anxiolytic-Like Action of Neuropeptide Y: Mediation by Y1 Receptors in Amygdala, and Dissociation from Food Intake Effects

1993 • 363 citations

Neurochemistry and pharmacology of the major hippocampal transmitter systems: Synaptic and nonsynaptic interactions

1998 • 362 citations

The interplay of learning and anxiety in the elevated plus-maze

1993 • 327 citations

Corticotropin-releasing factor and neuropeptide y: role in emotional integration

1994 • 320 citations

Structure and expression of the rat neuropeptide Y gene.

1987 • 300 citations

Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors

1997 • 246 citations

Life without neuropeptide Y.

1998 • 244 citations

Molecular cloning of a novel G protein‐coupled receptor that may belong to the neuropeptide receptor family

1990 • 240 citations

Amygdalar neuropeptide Y Y1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test

1999 • 239 citations

The Role of Corticotropin‐Releasing Factor in Behavioural Responses to Stress

2007 • 235 citations

Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions

1997 • 229 citations

Neuropeptide Y action in the rat hippocampal slice: site and mechanism of presynaptic inhibition

1988 • 220 citations

An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs

1993 • 218 citations

Inhibition of Synaptic Transmission by Neuropeptide Y in Rat Hippocampal Area CA1: Modulation of Presynaptic Ca²⁺Entry

1997 • 207 citations

Behavioral effects of neuropeptide Y receptor agonists in the elevated plus-maze and fear-potentiated startle procedures

1995 • 190 citations

Y₁ and Y₂ receptors for neuropeptide Y

1989 • 183 citations

Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding

1995 • 182 citations

Behavioral and endocrine adaptation, and up-regulation of NPY expression in rat amygdala following repeated restraint stress

1999 • 158 citations

Anxiolytic-like effect of neuropeptide Y (NPY), but not other peptides in an operant conflict test

1992 • 128 citations

BIIE0246, a potent and highly selective non‐peptide neuropeptide Y Y₂ receptor antagonist

2000 • 114 citations

Age-related deficits on the radial maze and in fear conditioning: Hippocampal processing and consolidation

1998 • 112 citations

Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment

1998 • 105 citations

Anxiogenic-like effect of the neuropeptide Y Y1 receptor antagonist BIBP3226: antagonism with diazepam

1996 • 94 citations

Neuropeptide Y2 receptors inhibit the frequency of spontaneous but not miniature EPSCs in CA3 pyramidal cells of rat hippocampus

1996 • 89 citations

Reduced dorsal hippocampal glutamate release significantly correlates with the spatial memory deficits produced by benzodiazepines and ethanol

1998 • 86 citations

Effects of neonatal stimulation on later cognitive function and hippocampal nerve growth factor

1997 • 85 citations

Dissociation of impairment between spatial memory, and motor function and emotional behavior in aged rats

1998 • 81 citations

Selectively Bred Lines of Rats Differ in Social Interaction and Hippocampal 5-HT1A Receptor Function: A Link Between Anxiety and Depression?

1998 • 67 citations

Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat

1987 • 56 citations

Evidence that the median raphé nucleus - dorsal hippocampal pathway mediates diazepam withdrawal-induced anxiety

1997 • 56 citations

The anxiolytic-like effect of metabotropic glutamate receptor antagonists after intrahippocampal injection in rats

1997 • 55 citations

Neuropeptide Y inhibits glutamate release and long-term potentiation in rat dentate gyrus

1999 • 52 citations

[¹²⁵I]‐GR231118: a high affinity radioligand to investigate neuropeptide Y Y₁ and Y₄ receptors

2000 • 41 citations

Effects of Psychoactive Drugs in the Vogel Conflict Test in Mice

1999 • 36 citations

Neuropeptide-Y Family of Peptides in the Autocrine-Paracrine Regulation of Adrenocortical Function

1998 • 34 citations

5-HT systems and anxiety: multiple mechanisms in the elevated X-maze.

1996 • 16 citations

Endogenous neuropeptide Y regulates thyroid blood flow

1993 • 14 citations

An Expanding Journal and the Quality of Research

1996 • 1 citations