Bacterial toxins: cellular mechanisms of action

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

Lysosomotropic agents

1974 • 1,887 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L

1964 • 1,298 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Endocytosis

1977 • 1,275 citations

Receptor-Mediated Control of Cholesterol Metabolism

1976 • 957 citations

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.

1982 • 929 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.

1982 • 808 citations

On the entry of semliki forest virus into BHK-21 cells

1980 • 808 citations

Diphtheria Toxin

1977 • 780 citations

One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell

1978 • 744 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1977 • 688 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles.

1976 • 663 citations

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1978 • 647 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

The origin, structure, and pharmacological activity of botulinum toxin.

1981 • 637 citations

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.

1975 • 619 citations

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans

1976 • 618 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

ADP ribosylation of the specific membrane protein of C6 cells by islet-activating protein associated with modification of adenylate cyclase activity.

1982 • 600 citations

Identification of the predominant substrate for ADP-ribosylation by islet activating protein.

1983 • 583 citations

Diphtheria toxin: mode of action and structure

1975 • 552 citations

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 • 535 citations

Actions of cholera toxin and the prevention and treatment of cholera

1981 • 532 citations

Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model

1982 • 497 citations

Purification of the regulatory component of adenylate cyclase.

1980 • 497 citations

Specific uncoupling by islet-activating protein, pertussis toxin, of negative signal transduction via alpha-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells.

1983 • 493 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

1981 • 424 citations

Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes.

1983 • 406 citations

Activation of Adenylate Cyclase by Choleragen

1979 • 394 citations

Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor.

1977 • 391 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Collection of insulin, EGF and α2-Macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization

1978 • 372 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Adsorptive endocytosis of Semliki Forest virus

1980 • 354 citations

pH-dependent fusion between the Semliki Forest virus membrane and liposomes.

1980 • 344 citations

Ammonia inhibits phagosome–lysosome fusion in macrophages

1980 • 339 citations

The arrangement of subunits in chlorea toxin

1976 • 337 citations

Modification by islet-activating protein of receptor-mediated regulation of cyclic AMP accumulation in isolated rat heart cells.

1981 • 326 citations

Epidermal growth factor. Relationship between receptor regulation and mitogenesis in 3T3 cells.

1978 • 324 citations

ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products.

1980 • 323 citations

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339.

1975 • 306 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Clostridium botulinum neurotoxin

1980 • 289 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

1981 • 281 citations

Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons

1975 • 277 citations

Calmodulin activates prokaryotic adenylate cyclase.

1980 • 276 citations

Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo

1977 • 266 citations

Colicin K acts by forming voltage-dependent channels in phospholipid bilayer membranes

1978 • 263 citations

Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

1980 • 252 citations

5′-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells

1974 • 244 citations

Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness.

1976 • 240 citations

Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.

1982 • 239 citations

Amines inhibit the clustering of α2-macroglobulin and EGF on the fibroblast cell surface

1979 • 237 citations

Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles.

1982 • 234 citations

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions.

1979 • 232 citations

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

1979 • 229 citations

A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells.

1983 • 227 citations

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study.

1979 • 223 citations

Membrane receptors for bacterial toxins

1983 • 222 citations

Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.

1982 • 221 citations

Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A.

1978 • 220 citations

Chicken ovalbumin contains an internal signal sequence

1979 • 216 citations

Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.

1976 • 212 citations

Thyrotropin-ganglioside interactions and their relationship to the structure and function of thyrotropin receptors.

1976 • 208 citations

The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit.

1981 • 201 citations

Mechanism of action of cholera toxin

1980 • 199 citations

Nascent prehormones are intermediates in the biosynthesis of authentic bovine pituitary growth hormone and prolactin.

1977 • 199 citations

Enzymatically active peptide from the adenosine diphosphate-ribosylating toxin of Pseudomonas aeruginosa

1977 • 196 citations

Association of diphtheria toxin with Vero cells. Demonstration of a receptor.

1978 • 195 citations

Amino‐Acid Sequence of a Heat‐Stable Enterotoxin Produced by Human Enterotoxigenic Escherichia coli

1982 • 190 citations

Role of gangliosides in the uptake and retrograde axonal transport of cholera and tetanus toxin as compared to nerve growth factor and wheat germ agglutinin

1977 • 188 citations

Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells.

1983 • 187 citations

Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation.

1979 • 185 citations

Receptor-mediated internalization of pseudomonas toxin by mouse fibroblasts

1980 • 176 citations

Subunit structure of Shigella cytotoxin.

1981 • 174 citations

Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin in vitro.

1975 • 171 citations

Modulation by islet-activating protein of adenylate cyclase activity in C6 glioma cells.

1982 • 164 citations

Activation of Adenylate Cyclase by Heat-Labile Escherichia Coli Enterotoxin

1978 • 163 citations

Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region.

1978 • 153 citations

Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.

1983 • 153 citations

Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: differential cytotoxicity

1977 • 149 citations

Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP ribosylation of the GTP-dependent regulatory component.

1980 • 148 citations

Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein).

1983 • 148 citations

Electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: An autoradiographic and morphometric study

1976 • 147 citations

Slow interaction of islet-activating protein with pancreatic islets during primary culture to cause reversal of alpha-adrenergic inhibition of insulin secretion.

1980 • 143 citations

Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa

1977 • 142 citations

The penetration of reovirus RNA and initiation of its genetic function in L-strain fibroblasts.

1968 • 140 citations

Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments.

1976 • 139 citations

Tetanus toxin fragment forms channels in lipid vesicles at low pH.

1982 • 138 citations

Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts.

1980 • 138 citations

Rat liver pre-proalbumin: complete amino acid sequence of the pre-piece. Analysis of the direct translation product of albumin messenger RNA.

1977 • 135 citations

Lysomotropic amines cause intracellular accumulation of receptors for epidermal growth factor.

1980 • 134 citations

Selective trans-synaptic migration of tetanus toxin after retrograde axonal transport in peripheral sympathetic nerves: A comparison with the nerve growth factor

1977 • 134 citations

INTERACTION OF CHOLERA TOXIN AND TOXIN DERIVATIVES WITH LYMPHOCYTES

1974 • 133 citations

Soluble adenylate cyclase from the culture medium of Bordetella pertussis: purification and characterization

1976 • 131 citations

Adenosine Diphosphate-Ribosylation of Adenylate Cyclase Catalyzed by Heat-Labile Enterotoxin of Escherichia coli: Comparison with Cholera Toxin

1980 • 128 citations

Mobility of cholera toxin receptors on rat lymphocyte membranes.

1975 • 124 citations

Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells

1979 • 120 citations

Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.

1975 • 119 citations

Diphtheria toxin. Site and configuration of ADP-ribosylation of diphthamide in elongation factor 2.

1981 • 115 citations

Interaction of diphtheria toxin with mammalian cell membranes.

1976 • 112 citations

A regulatory component of adenylate cyclase from human erythrocyte membranes.

1980 • 109 citations

Inhibition of diphtheria toxin degradation and cytotoxic action by chloroquine.

1980 • 109 citations

Elongation Factor 2

1974 • 108 citations

Isolation and characterization of Shigella shigae cytotoxin.

1980 • 107 citations

Structural determination and stereospecificity of the choleragen-catalyzed reaction of NAD+ with guanidines.

1978 • 107 citations

Antihistaminics, local anesthetics, and other amines as antiviral agents.

1981 • 104 citations

Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin

1975 • 103 citations

Binding and internalization of 125I-alpha 2-macroglobulin by cultured fibroblasts.

1981 • 103 citations

Effect of chloroquine on the internalization of 125I-insulin into subcellular fractions of rat liver. Evidence for an effect of chloroquine on Golgi elements.

1982 • 102 citations

Endocytosis of cholera toxin into neuronal GERL.

1978 • 101 citations

Selection and characterization of cells resistant to diphtheria toxin and pseudomonas exotoxin A: presumptive translational mutants

1977 • 101 citations

Endocytosis of cholera toxin in GERL-like structures of murine neuroblastoma cells pretreated with GM1 ganglioside. Cholera toxin internalization into Neuroblastoma GERL.

1979 • 99 citations

Sequence similarity between cholera toxin and glycoprotein hormones: Implications for structure activity relationship and mechanism of action

1976 • 98 citations

Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells.

1979 • 90 citations

In Vitro Inhibition of Diphtheria Toxin Action by Ammonium Salts and Amines

1965 • 89 citations

Tetanus toxin interactions with thyroid plasma membranes. Implications for structure and function of tetanus toxin receptors and potential pathophysiological significance.

1977 • 88 citations

Receptor-mediated endocytosis of diphtheria toxin by cells in culture.

1982 • 88 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

1978 • 87 citations

Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits

1979 • 87 citations

Bacteremia Due To Pseudomonas aeruginosa Complicating Neoplastic Disease: A Progress Report

1974 • 87 citations

Monensin blocks the transport of diphtheria toxin to the cell cytoplasm.

1982 • 86 citations

Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia

1979 • 85 citations

Role of Microtubules in Low Density Lipoprotein Processing by Cultured Cells

1979 • 85 citations

Posttranslational modification of elongation factor 2 in diphtheria-toxin-resistant mutants of CHO-K1 cells.

1980 • 85 citations

The exotoxin of P. Aeruginosa: A proenzyme having an unusual mode of activation

1978 • 79 citations

Ultrastructural analysis of toxin binding and entry into mammalian cells

1974 • 77 citations

Primary structure of diphtheria toxin fragment B: structural similarities with lipid-binding domains.

1980 • 77 citations

Dissociation of tetanus neurotoxin into two polypeptide fragments

1974 • 75 citations

Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells

1979 • 75 citations

Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin.

1983 • 75 citations

Guanine nucleotide activation and inhibition of adenylate cyclase as modified by islet-activating protein, pertussis toxin, in mouse 3T3 fibroblasts

1983 • 73 citations

Lysosomotropic amines inhibit mitogenesis induced by growth factors.

1981 • 73 citations

NAD-dependent ADP-ribosylation of arginine and proteins by Escherichia coli heat-labile enterotoxin.

1979 • 73 citations

Protein mediated vitamin uptake

1979 • 73 citations

The interaction between aminoquinolines and presynaptically acting neurotoxins.

1982 • 71 citations

Mechanism of Activation of Adenylate Cyclase in Vitro by Polymyxin-Released, Heat-Labile Enterotoxin of Escherichia coli

1976 • 71 citations

Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.

1977 • 71 citations

Transmembrane interactions and the mechanisms of transport of proteins across membranes

1978 • 71 citations

Fate of plasma membrane during endocytosis. I. Uptake and processing of anti-plasma membrane and control immunoglobulins by cultured fibroblasts.

1979 • 70 citations

Pathogenesis of shigella diarrhea. VII. Evidence for a cell membrane toxin receptor involving β1 {arrow} 4-linked N-acetyl-D-glucosamine oligomers

1977 • 70 citations

Inhibition of protein synthesis by Shiga toxin

1980 • 68 citations

Polypeptide hormone degradation and receptor regulation are coupled to ligand internalization. A direct biochemical and morphologic demonstration.

1981 • 67 citations

Bilayers containing gangliosides develop channels when exposed to cholera toxin

1978 • 67 citations

Characterization of the diphtheria toxin-resistance system in Chinese hamster ovary cells

1979 • 66 citations

The Pathogenesis of Shigella Diarrhea. V. Relationship of Shiga Enterotoxin, Neurotoxin, and Cytotoxin

1975 • 66 citations

Methylamine stimulates the action of ricin toxin but inhibits that of diphtheria toxin.

1981 • 64 citations

Synthesis and assembly of membrane glycoproteins: presence of leader peptide in nonglycosylated precursor of membrane glycoprotein of vesicular stomatitis virus.

1979 • 62 citations

Quantitative Microassay in Cell Culture for Enterotoxin of Shigella dysenteriae 1

1972 • 61 citations

Tetanus toxin association with developing neuronal cell cultures. Kinetic parameters and evidence for ganglioside-mediated internalization.

1981 • 60 citations

Production of exoenzyme S during Pseudomonas aeruginosa infections of burned mice

1979 • 60 citations

Suppression of 3H-acetylcholine release from primary nerve cell cultures by tetanus and botulinum-A toxin

1978 • 54 citations

Receptor-mediated entry of Pseudomonas toxin: methylamine blocks clustering step

1983 • 53 citations

Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells.

1981 • 51 citations

Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells.

1983 • 51 citations

Effect of the A and B protomers of choleragen on release of trapped glucose from liposomes containing or lacking ganglioside GM1.

1977 • 50 citations

THE RESPONSE OF CULTURED MAMMALIAN CELLS TO DIPHTHERIA TOXIN

1968 • 49 citations

Infections Caused by Pseudomonas Species in Patients with Burns and in Other Surgical Patients

1974 • 48 citations

ADP-ribosylation of membrane proteins and activation of adenylate cyclase by cholera toxin in fat cell ghosts from euthyroid and hypothyroid rats

1979 • 48 citations

Isolation and characterization of mutants of human diploid fibroblasts resistant to diphtheria toxin.

1978 • 47 citations

STUDIES ON THE MODE OF ACTION OF DIPHTHERIA TOXIN

1968 • 47 citations

Chemical modulation of diphtheria toxin action on cultured mammalian cells

1975 • 45 citations

Inhibition of invitro protein synthesis by Shigelladysenteriae 1 toxin

1976 • 44 citations

Codominant translational mutants of Chinese hamster ovary cells selected with diphtheria toxin

1979 • 44 citations

Acute botulinum-like intoxication by tetanus neurotoxin in mice

1982 • 42 citations

Cholera toxin modifies diverse GTP-modulated regulatory proteins

1981 • 42 citations

Diphtheria toxin has the properties of a lectin.

1978 • 41 citations

Interaction of cultured mammalian cells with [125I] diphtheria toxin

1975 • 41 citations

Biochemical and genetic characterization of three hamster cell mutants resistant to diphtheria toxin

1979 • 41 citations

Enzymatic breakdown of tetanus toxin

1974 • 40 citations

Antigenic substructure of tetanus neurotoxin

1977 • 39 citations

Comparative Toxicities of Diphtherial Toxin and Pseudomonas aeruginosa Exotoxin A: Evidence for Different Cell Receptors

1978 • 39 citations

Production and Characterization of Exotoxin(s) of Shigella dysenteriae Type 1

1975 • 37 citations

Differential chemical protection of mammalian cells from the exotoxins of Corynebacterium diphtheriae and Pseudomonas aeruginosa

1977 • 35 citations

Response of Cultured Mammalian Cells to Diphtheria Toxin IV. Isolation of KB Cells Resistant to Diphtheria Toxin

1972 • 34 citations

Cholera toxin can catalyze ADP-ribosylation of cytoskeletal proteins.

1981 • 33 citations

Intracellular stability of diphtheria toxin fragment A in the presence and absence of anti-fragment A antibody.

1982 • 33 citations

STUDIES ON THE MODE OF ACTION OF DIPHTHERIA TOXIN

1967 • 33 citations

Fluorescence Studies on Substrate Binding to Seryl‐tRNA Synthetase from Yeast

1972 • 31 citations

Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.

1978 • 30 citations

Comparison of diphtheria intoxication in human and nonhuman cell lines and their resistant variants

1976 • 28 citations

The Formation of a Ternary Complex between Diphtheria Toxin, Aminoacyltransferase II, and Diphosphopyridine Nucleotide

1970 • 28 citations

Diphtheria toxin resistance in chinese hamster cells: Genetic and biochemical characteristics of the mutants affected in protein synthesis

1980 • 28 citations

Tubulin adenosine diphosphate ribosylation is catalyzed by cholera toxin

1982 • 28 citations

Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa

1981 • 28 citations

Exposure of cells to an acidic environment reverses the inhibiton by methylamine of the mitogenic response to epidermal growth factor

1982 • 26 citations

Cytotoxicity of Shigella dysenteriae 1 for cultured mammalian cells

1980 • 26 citations

Toxicity of pseudomonas toxin for mouse LM cell fibroblasts

1979 • 23 citations

Recognition of elongation factor 2 by diphtheria toxin is not solely defined by the presence of diphthamide

1980 • 23 citations

Interaction of diphtheria toxin and its active subunit, fragment A, with toxin-sensitive and toxin-resistant cells

1976 • 23 citations

Effects of lectins on the interaction of diphtheria toxin with mammalian cells

1979 • 23 citations

Comparison of the effects of cholera enterotoxin and ACTH on adrenal cells in tissue culture

1974 • 21 citations

Diphtheria toxin does not enter resistant cells by receptor-mediated endocytosis

1983 • 21 citations

Response of Cultured Mammalian Cells to Diphtheria Toxin V. Concurrent Resistance to Ribonucleic Acid Viruses in Diphtheria Toxin-Resistant KB Cell Strains

1972 • 20 citations

Tetanus toxin action on cultured nerve cells does it modify a neuronal protein?

1982 • 20 citations

Uptake of diphtheria toxin and its fragment A moiety by mammalian cells in culture

1976 • 19 citations

Inhibitors of protein synthesis block action of cholera toxin

1981 • 19 citations

RECEPTOR-MEDIATED ENDOCYTOSIS OF SHIGELLA CYTOTOXIN

1981 • 18 citations

Tetanus Toxin Inhibition of K⁺ ‐Stimulated [³H]GABA Release from Developing Cell Cultures of the Rat Cerebellum

1983 • 18 citations

Tetanus Toxin Interactions with the Thyroid: Decreased Toxin Binding to Membranes from a Thyroid Tumor with a Thyrotropin Receptor Defect andin VivoStimulation of Thyroid Function

1978 • 17 citations

Effect of ammonium chloride on receptor-mediated uptake of diphtheria toxin by Vero cells

1981 • 16 citations

Binding and Uptake of Diphtheria Toxin by Toxin-Resistant Chinese Hamster Ovary and Mouse Cells

1983 • 11 citations

The protective mechanism of action of amines in diphtheria toxin treated Vero cells

1982 • 11 citations

Differential sensitivity of reticulocytes to nicked and unnicked diphtheria toxin

1982 • 9 citations

Antagonism of botulinum toxin by theophylline

1976 • 9 citations

Transport of diphtheria toxin A fragment across the plasma membrane.

1979 • 7 citations

Interaction of Toxin of Corynebacterium diphtheriae with Phagocytes from Susceptible and Resistant Species

1975 • 6 citations

RECEPTOR-MEDIATED ENDOCYTOSIS OF HORMONES IN CULTURED FIBROBLASTS

1981 • 6 citations

Interaction of diphtheria toxin with mammalian cell membranes.

1977 • 6 citations

Studies on the MgSO4-induced cytoplasmic uptake of proteins by cells in culture

1977 • 6 citations

UPTAKE MECHANISMS FOR ADP-RIBOSYLATING TOXINS

1981 • 5 citations

Cholera toxin covalently linked with horseradish peroxidase does not activate the adenylate cyclase of neuroblastoma cells

1982 • 4 citations

DIPHTHERIA TOXIN: A MODEL FOR TRANSLOCATION OF POLYPEPTIDES ACROSS THE PLASMA MEMBRANE

1981 • 4 citations

ENDOCYTOSIS OF CHOLERA TOXIN AND H3GM1 GANGLIOSIDE BY NEUROBLASTOMA CELLS

1981 • 3 citations

CHOLERA TOXIN'S INTERACTIONS WITH CELL MEMBRANES

1981 • 3 citations

RECEPTOR-MEDIATED INTERNALIZATION OF DIPHTHERIA TOXIN

1981 • 2 citations

RECEPTOR-MEDIATED BINDING AND INTERNALIZATION OF PSEUDOMONAS EXOTOXIN A AND DIPHTHERIA EXOTOXIN BY MAMMALIAN CELLS

1980 • 2 citations

Two Antigenically Active, Complementary Polypeptide Fragments of Tetanus Neurotoxin

1976 • 2 citations