Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries

Initial sequencing and analysis of the human genome

2001 • 23,520 citations

The Sequence of the Human Genome

2001 • 13,500 citations

Recent Segmental Duplications in the Human Genome

2002 • 1,342 citations

Unmasking Multivariate Outliers and Leverage Points

1990 • 1,332 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Controlling the double helix

2003 • 1,102 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage

2003 • 721 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

2002 • 619 citations

A Global Control Region Defines a Chromosomal Regulatory Landscape Containing the HoxD Cluster

2003 • 470 citations

Computational identification of promoters and first exons in the human genome

2001 • 411 citations

Genomic strategies to identify mammalian regulatory sequences

2001 • 389 citations

Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo

2001 • 378 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

Whole-Genome Analysis of Dorsal-Ventral Patterning in the Drosophila Embryo

2002 • 295 citations

The insulation of genes from external enhancers and silencing chromatin

2002 • 291 citations

Chromatin Unfolds

1996 • 253 citations

Comparative genomics: genome-wide analysis in metazoan eukaryotes

2003 • 236 citations

Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus.

1983 • 190 citations

The eukaryotic genome: a system regulated at different hierarchical levels

2003 • 180 citations

SLAM: Cross-Species Gene Finding and Alignment with a Generalized Pair Hidden Markov Model

2003 • 177 citations

Locus control regions, chromatin activation and transcription

1998 • 142 citations

Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene.

1989 • 124 citations

Molecular biology: Anatomy of hypersensitive sites

1984 • 119 citations

An Enhancer/Locus Control Region Is Not Sufficient To Open Chromatin

1993 • 90 citations

Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse β-globin LCR 1 1Edited by J. Karn

2001 • 89 citations

Human p53 oncogene contains one promoter upstream of exon 1 and a second, stronger promoter within intron 1.

1988 • 88 citations

An element in intron 1 of the CFTR gene augments intestinal expression in vivo

2001 • 65 citations

An intron 1 enhancer element mediates oestrogen-induced suppression of ERBB2 expression

1997 • 63 citations

Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human α2(I) Collagen (COL1A2) Gene

2001 • 48 citations

Multiple control elements are required for expression of the human CD34 gene

1998 • 28 citations

High Level Transcription of the Complement Regulatory Protein CD59 Requires an Enhancer Located in Intron 1

1999 • 19 citations

Numerical methods for handling uncertainty in microarray data: An example analyzing perturbed mitochondrial function in yeast

2001 • 19 citations