Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

The GTP-binding protein, Go9 regulates neuronal calcium channels

1987 • 910 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1983 • 659 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Pertussis toxin-catalyzed ADP-ribosylation of transducin. Cysteine 347 is the ADP-ribose acceptor site.

1985 • 457 citations

Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning

1987 • 441 citations

Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase

1985 • 325 citations

The α Subunit of the GTP Binding Protein G _k Opens Atrial Potassium Channels

1987 • 317 citations

Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence

1987 • 284 citations

Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells. Reconstitution with Gi or Go of the plasma membranes ADP-ribosylated by pertussis toxin.

1986 • 276 citations

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

1988 • 275 citations

Newly Identified Brain Potassium Channels Gated by the Guanine Nucleotide Binding Protein G _o

1988 • 236 citations

Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles.

1986 • 199 citations

Molecular cloning and expression of a fifth muscarinic acetylcholine receptor

1989 • 182 citations

Goprotein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway

1990 • 181 citations

Differential G protein—mediated coupling of neurotransmitter receptors to Ca2+ channels in rat dorsal root ganglion neurons in vitro

1989 • 180 citations

Carboxyl Rerminal Domain of G _sα Specifies Coupling of Receptors to Stimulation of Adenylyl Cyclase

1988 • 174 citations

Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go

1988 • 153 citations

Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons

1989 • 124 citations

G-protein distribution in canine cardiac sarcoplasmic reticulum and sarcolemma: Comparison to rabbit skeletal muscle membranes and to brain and erythrocyte G-proteins

1987 • 115 citations

Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels.

1988 • 104 citations

Identification by molecular cloning of two forms of the α‐subunit of the human liver stimulatory (G_s) regulatory component of adenylyl cyclase

1986 • 96 citations

Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

1987 • 95 citations

Competitive mRNA translation in an in vitro system from wheat germ.

1979 • 91 citations

G protein mRNA mapped in rat brain by in situ hybridization.

1988 • 86 citations

The Drosophila Go α-like G protein gene produces multiple transcripts and is expressed in the nervous system and in ovaries

1989 • 74 citations

Molecular characterization of Drosophila Gene Encoding G0 α Subunit Homolog

1989 • 72 citations

The Drosophila gene coding for the alpha subunit of a stimulatory G protein is preferentially expressed in the nervous system.

1989 • 65 citations

Molecular cloning and sequence determination of a cDNA coding for the α‐subunit of a G_o‐type protein of Xenopus laevis oocytes

1989 • 57 citations

Reticulocyte lysates synthesize an active alpha subunit of the stimulatory G protein Gs.

1988 • 48 citations

Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit.

1989 • 40 citations