Identification by molecular cloning of two forms of the α‐subunit of the human liver stimulatory (G_s) regulatory component of adenylyl cyclase

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Yeast RNA Polymerase II Genes: Isolation with Antibody Probes

1983 • 1,084 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels

1979 • 564 citations

The regulatory component of adenylate cyclase. Purification and properties.

1981 • 505 citations

Purification of the regulatory component of adenylate cyclase.

1980 • 497 citations

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

1986 • 341 citations

Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase

1985 • 325 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands.

1984 • 242 citations

Identification of a gamma subunit associated with the adenylyl cyclase regulatory proteins Ns and Ni.

1984 • 214 citations

Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase

1985 • 209 citations

Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.

1986 • 177 citations

Primary structure of the α‐subunit of bovine adenylate cyclase‐stimulating G‐protein deduced from the cDNA sequence

1986 • 142 citations

Glucagon-induced heterologous desensitization of the MDCK cell adenylyl cyclase. Increases in the apparent levels of the inhibitory regulator (Ni).

1984 • 119 citations

Different mechanisms of desensitization of adenylate cyclase by isoproterenol and prostaglandin E1 in human fibroblasts. Role of regulatory components in desensitization.

1982 • 115 citations

A regulatory component of adenylate cyclase from human erythrocyte membranes.

1980 • 109 citations

The ovalbumin gene: Cloning of the natural gene

1978 • 72 citations

Peptide mapping of adenylate cyclase regulatory proteins that are cholera toxin substrates.

1980 • 47 citations

Cholera toxin modifies diverse GTP-modulated regulatory proteins

1981 • 42 citations

ADP ribosylation of membrane proteins from human fibroblasts. Effect of prior exposure of cells to choleragen.

1981 • 41 citations

Effects of guanine nucleotides on cholera toxin catalyzed ADP-ribosylation in rat adipocyte plasma membranes

1983 • 22 citations

Mechanism of action of glycopeptide hormones and cholera toxin: what is the role of ADP-ribosylation?

1983 • 21 citations

An Mr = 52,000 peptide can mediate effects on cholera toxin on adenylate cyclase in intact cells.

1981 • 19 citations

The emergence of modern man

1980 • 13 citations

Peptide mapping of fat cell membrane substrates for cholera toxin-catalyzed ADP-ribosylation

1982 • 12 citations