REPERFUSION INJURY AFTER LIVER PRESERVATION FOR TRANSPLANTATION

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

J. Submicrosc. Cytol. Pathol.

2000 • 2,783 citations

Mechanisms by which mitochondria transport calcium

1990 • 1,630 citations

PRINCIPLES OF SOLID-ORGAN PRESERVATION BY COLD STORAGE

1988 • 1,366 citations

RISK FACTORS FOR PRIMARY DYSFUNCTION AFTER LIVER TRANSPLANTATION—A MULTIVARIATE ANALYSIS

1993 • 1,037 citations

Evolution of Liver Transplantation

1982 • 873 citations

PRESERVATION AND REPERFUSION INJURIES IN LIVER ALLOGRAFTS

1992 • 836 citations

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

1990 • 828 citations

Cells of the hepatic sinusoid

1989 • 589 citations

Selecting the donor liver: Risk factors for poor function after orthotopic liver transplantation

1994 • 542 citations

SINUSOIDAL LINING CELL DAMAGE

1988 • 458 citations

Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion

1991 • 409 citations

PRIMARY NONFUNCTION OF HEPATIC ALLOGRAFTS WITH PREEXISTING FATTY INFILTRATION1

1989 • 364 citations

Reperfusion injury to endothelial cells following cold ischemic storage of rat livers

1989 • 356 citations

Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes

1993 • 337 citations

Evaluation of the electroinjection method for introducing proteins into living cells

1991 • 303 citations

Transplantation of the Liver

1996 • 278 citations

Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules.

1987 • 274 citations

Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes

1988 • 265 citations

Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A

1991 • 261 citations

TREATMENT OF PRIMARY LIVER GRAFT NONFUNCTION WITH PROSTAGLANDIN E1

1989 • 256 citations

Contribution of No-reflow phenomenon to hepatic injury after ischemia-reperfusion: Evidence for a role for superoxide anion

1992 • 225 citations

EFFECT OF COLD ISCHEMIA TIME ON THE EARLY OUTCOME OF HUMAN HEPATIC ALLOGRAFTS PRESERVED WITH UW SOLUTION

1991 • 223 citations

Cell biology of liver endothelial and Kupffer cells.

1994 • 208 citations

HEPATIC REPERFUSION INJURY FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

1988 • 196 citations

Hepatic Microcirculatory Changes After Reperfusion In Fatty And Normal Liver TrANSPLANTATION IN THE RAT

1993 • 185 citations

Selective loss of nonparenchymal cell viability after cold ischemic storage of rat livers.

1988 • 179 citations

INCREASE IN SURVIVAL TIME OF LIVER TRANSPLANTS BY PROTEASE INHIBITORS AND A CALCIUM CHANNEL BLOCKER, NISOLDIPINE

1990 • 160 citations

SELECTIVE LOSS OF NONPARENCHYMAL CELL VIABILITY AFTER COLD ISCHEMIC STORAGE OF RAT LIVERS

1988 • 153 citations

Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox

1991 • 152 citations

LEUKOCYTE ADHESION AND CELL DEATH FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

1991 • 149 citations

Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: Protection by allopurinol

1988 • 139 citations

EVIDENCE THAT GRAFT SURVIVAL IS NOT RELATED TO PARENCHYMAL CELL VIABILITY IN RAT LIVER TRANSPLANTATION

1989 • 133 citations

Protection by acidotic pH against anoxia/reoxygenation injury to rat neonatal cardiac myocytes

1991 • 131 citations

EVIDENCE THAT FREE RADICALS ARE INVOLVED IN GRAFT FAILURE FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT—AN ELECTRON PARAMAGNETIC RESONANCE SPIN TRAPPING STUDY

1992 • 131 citations

CAROLINA RINSE SOLUTION—A NEW STRATEGY TO INCREASE SURVIVAL TIME AFTER ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

1991 • 114 citations

Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress.

1993 • 107 citations

Reduction by superoxide dismutase of leukocyte-endothelial adherence after liver transplantation.

1992 • 89 citations

Glycine cytoprotection during lethal hepatocellular injury from adenosine triphosphate depletion

1992 • 86 citations

Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: Evidence for A2 receptors on rat kupffer cells

1994 • 82 citations

PREDICTION OF THE OUTCOME OF TRANSPLANTATION IN MAN BY PLATELET ADHERENCE IN DONOR LIVER ALLOGRAFTS

1993 • 81 citations

Tumor necrosis factor and endotoxin in the pathogenesis of liver and pulmonary injuries after orthotopic liver transplantation in the rat

1992 • 81 citations

THE EFFECTS OF COLD PRESERVATION ON STEATOTIC GRAFT VIABILITY IN RAT LIVER TRANSPLANTATION

1993 • 78 citations

A double-blind, randomized, placebo-controlled trial of prostaglandinE1 in liver transplantation

1995 • 76 citations

Regulation of Nitric Oxide Production by Stimulated Rat Kupffer Cells

1991 • 75 citations

Mitochondrial dysfunction during anoxia/reoxygenation injury of liver sinusoidal endothelial cells

1994 • 75 citations

Translocation of Bacteria and Endotoxin in Organ Donors

1994 • 70 citations

PRIMARY NONFUNCTION OF FATTY LIVERS PRODUCED BY ALCOHOL IS ASSOCIATED WITH A NEW, ANTIOXIDANT-INSENSITIVE FREE RADICAL SPECIES

1995 • 68 citations

EVIDENCE THAT CAROLINA RINSE SOLUTION PROTECTS SINUSOIDAL ENDOTHELIAL CELLS AGAINST REPERFUSION INJURY AFTER COLD ISCHEMIC STORAGE OF RAT LIVER

1990 • 67 citations

A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes

1991 • 65 citations

Evidence that Carolina rinse solution protects sinusoidal endothelial cells against reperfusion injury after cold ischemic storage of rat liver.

1990 • 65 citations

Preservation of human liver grafts in UW solution. Ultrastructural evidence for endothelial and Kupffer cell activation during cold ischemia and after ischemia‐reperfusion

1994 • 59 citations

INCREASE IN SURVIVAL OF LIVER GRAFTS AFTER RINSING WITH WARM RINGERʼS SOLUTION DUE TO IMPROVEMENT OF HEPATIC MICROCIRCULATION

1991 • 57 citations

Reperfusion injury to endothelial cells after cold storage of rat livers: protection by mildly acidic pH and lack of protection by antioxidants

1995 • 54 citations

EVIDENCE THAT ADENOSINE IS A KEY COMPONENT IN CAROLINA RINSE RESPONSIBLE FOR REDUCING GRAFT FAILURE AFTER ORTHOTOPIC LIVER TRANSPLANTATION IN THE RAT

1991 • 51 citations

EFFECT OF GLYCINE IN DOG AND RAT LIVER TRANSPLANTATION

1993 • 50 citations

Suppression of Ca2+ oscillations in cultured rat hepatocytes by chemical hypoxia.

1991 • 50 citations

Warm Carolina rinse solution prevents graft failure from storage injury after orthotopic rat liver transplantation with arterialization

1992 • 46 citations

Destruction of Kupffer cells increases survival and reduces graft injury after transplantation of fatty livers from ethanol-treated rats

1996 • 46 citations

Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium

1995 • 44 citations

Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion,

1991 • 44 citations

EFFECTS OF CAROLINA RINSE AND ADENOSINE RINSE ON MICROVASCULAR PERFUSION AND INTRAHEPATIC LEUKOCYTE-ENDOTHELIUM INTERACTION AFTER LIVER TRANSPLANTATION IN THE RAT

1993 • 42 citations

THE EFFECTS OF DONOR AND RECIPIENT ENDOTOXEMIA ON TNFcα PRODUCTION AND MORTALITY IN THE RAT MODEL OF SYNGENIC ORTHOTOPIC LIVER TRANSPLANTATION

1995 • 27 citations

Protection by pentoxifylline against graft failure from storage injury after orthotopic rat liver transplantation with arterialization

1992 • 22 citations

Evidence that both cyclosporin and azathioprine prevent warm ischemia reperfusion injury to the rat liver

1993 • 21 citations

Causes of death after liver transplantation in children treated with cyclosporine and steroids

1989 • 19 citations

Injury to cultured liver endothelial cells during cold preservation: energy-dependent versus energy-deficiency injury

1993 • 19 citations

Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: Evidence for A2 receptors on rat Kupffer cells,

1994 • 16 citations

Reperfusion rather than storage injury predominates following long-term (48 h) cold storage of grafts in UW solution: studies with Carolina Rinse in rat liver

1992 • 16 citations

THE EFFECTS OF PRETRANSPLANT CYCLOSPORINE THERAPY ON RATS GRAFTED WITH TWELVE-HOUR COLD-STORED LIVERS—WITH SPECIAL REFERENCE TO REPERFUSION INJURY

1991 • 15 citations

Mitochondrial dysfunction during anoxia/reoxygenation injury of liver sinusoidal endothelial cells*1, *2

1994 • 14 citations

Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium

1995 • 12 citations

Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress

1993 • 11 citations

A double-blind, randomized, placebo-controlled trial of prostaglandin E1 in liver transplantation*1

1995 • 10 citations

Stimulation of liver regeneration by pretreatment with azathioprine as well as cyclosporine and FK506.

1992 • 9 citations

STIMULATION OF LIVER REGENERATION BY PRETREATMENT WITH AZATHIOPRINE AS WELL AS CYCLO-SPORINE AND FK506

1992 • 6 citations