Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

The alphaviruses: gene expression, replication, and evolution

1994 • 1,952 citations

Hepatitis B Virus Immunopathogenesis

1995 • 1,568 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

A New Generation of Animal Cell Expression Vectors Based on the Semliki Forest Virus Replicon

1991 • 899 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo

1991 • 743 citations

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

1989 • 741 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells

1981 • 686 citations

Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants

1987 • 476 citations

A Defective HSV-1 Vector Expresses Escherichia coli β-Galactosidase in Cultured Peripheral Neurons

1988 • 417 citations

[40] Use of retroviral vectors for gene transfer and expression

1993 • 412 citations

Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells

1989 • 402 citations

Complete nucleotide sequence of the genomic RNA of Sindbis virus

1984 • 393 citations

Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs

1993 • 366 citations

Infectious Transcripts and cDNA Clones of RNA Viruses

1994 • 340 citations

A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA

1991 • 339 citations

Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis.

1994 • 311 citations

Semliki Forest Virus Expression System: Production of Conditionally Infectious Recombinant Particles

1993 • 290 citations

Vaccinia Virus Expression Vectors

1987 • 272 citations

Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1

1985 • 270 citations

Heterologous and Homologous Protection Against Influenza A by DNA Vaccination: Optimization of DNA Vectors

1993 • 267 citations

Infectious defective interfering particles of VSV from transcripts of a cDNA clone

1992 • 266 citations

Molecular basis of Sindbis virus neurovirulence in mice

1988 • 257 citations

Isolation and characterization of conditional-lethal mutants of Sindbis virus

1966 • 254 citations

In vitro synthesis of infectious venezuelan equine encephalitis virus RNA from a cDNA clone: Analysis of a viable deletion mutant

1989 • 235 citations

Histochemical staining of clonal mammalian cell lines expressingE. coli ? galactosidase indicates heterogeneous expression of the bacterial gene

1987 • 232 citations

Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.

1992 • 231 citations

Simian virus 40 early mRNA's. I. Genomic localization of 3' and 5' termini and two major splices in mRNA from transformed and lytically infected cells

1979 • 199 citations

Viral vector systems for gene therapy.

1994 • 193 citations

Self-replicating Semliki Forest virus RNA as recombinant vaccine

1994 • 189 citations

Evidence for specificity in the encapsidation of Sindbis virus RNAs

1989 • 167 citations

Deletion mapping of sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging

1986 • 160 citations

Transfected DNA is mutated in monkey, mouse, and human cells.

1984 • 138 citations

Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals

1984 • 121 citations

Recombination between Sindbis virus RNAs

1991 • 119 citations

Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon

1994 • 114 citations

Alphavirus expression systems

1994 • 105 citations

Initiation sites for translation of sindbis virus 42S and 26S messenger RNAs

1975 • 103 citations

The 3′-non-coding regions of alpharivus RNAs contain repeating sequences

1982 • 98 citations

Analysis of Sindbis virus promoter recognition in vivo, using novel vectors with two subgenomic mRNA promoters

1991 • 96 citations

Mutants of Sindbis virus

1976 • 93 citations

A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons

1988 • 78 citations

Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro

1988 • 77 citations

Alphaviruses ? vectors for the expression of heterologous genes

1993 • 75 citations

Complementation between Sindbis viral RNAs produces infectious particles with a bipartite genome.

1991 • 73 citations

Transfected DNA Is Mutated in Monkey, Mouse, and Human Cells

1984 • 67 citations

A Cell Line That Expresses a Reporter Gene in Response to Infection by Sindbis Virus: A Prototype for Detection of Positive Strand RNA Viruses

1994 • 39 citations

Highly infectious plasmids carrying poliovirus cDNA are capable of replication in transfected simian cells

1986 • 21 citations