Tissue-specific spatial organization of genomes

Numerical recipes in C

1994 • 15,831 citations

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

2001 • 2,239 citations

Differences in the Localization and Morphology of Chromosomes in the Human Nucleus

1999 • 902 citations

Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

1997 • 792 citations

Orchestrated response: a symphony of transcription factors for gene control

2000 • 763 citations

Subnuclear Compartmentalization of Immunoglobulin Loci During Lymphocyte Development

2002 • 708 citations

The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells

2001 • 673 citations

Proximity of Chromosomal Loci That Participate in Radiation-Induced Rearrangements in Human Cells

2000 • 457 citations

Spatial proximity of translocation-prone gene loci in human lymphomas

2003 • 408 citations

Tissue-specific nuclear architecture and gene expession regulated by SATB1

2003 • 404 citations

Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates

2002 • 389 citations

Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells.

2001 • 368 citations

Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer

2004 • 358 citations

Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages

2003 • 313 citations

Chromosome positioning in the interphase nucleus

2002 • 308 citations

Nuclear compartmentalization and gene activity

2000 • 292 citations

Global Chromosome Positions Are Transmitted through Mitosis in Mammalian Cells

2003 • 290 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

2000 • 270 citations

Inheritance of gene density–related higher order chromatin arrangements in normal and tumor cell nuclei

2003 • 253 citations

Evidence for Replicative Repair of DNA Double-Strand Breaks Leading to Oncogenic Translocation and Gene Amplification

2002 • 229 citations

The Nuclear Topography of ABL, BCR, PML, and RAR Genes: Evidence for Gene Proximity in Specific Phases of the Cell Cycle and Stages of Hematopoietic Differentiation

1999 • 204 citations

Conservation of Relative Chromosome Positioning in Normal and Cancer Cells

2002 • 190 citations

The Radial Positioning of Chromatin Is Not Inherited through Mitosis but Is Established De Novo in Early G1

2004 • 165 citations

Predicting three-dimensional genome structure from transcriptional activity

2002 • 164 citations

Non-Rabl patterns of centromere and telomere distribution in the interphase nuclei of plant cells.

1998 • 157 citations

Nuclear relocation of a transactivator subunit precedes target gene activation

2001 • 136 citations

The topological organization of chromosomes 9 and 22 in cell nuclei has a determinative role in the induction of t(9,22) translocations and in the pathogenesis of t(9,22) leukemias

1999 • 115 citations

3D Structure of the human genome: order in randomness

2002 • 105 citations

Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia

1997 • 105 citations

Chromosomes are predominantly located randomly with respect to each other in interphase human cells

2002 • 96 citations

Nuclear structure and gene activity in human differentiated cells

2002 • 65 citations

Nonrandom Cytogenetic Alterations in Hepatocellular Carcinoma from Transgenic Mice Overexpressing c-Myc and Transforming Growth Factor-α in the Liver

1999 • 56 citations