Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stability

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Multiple upstream AUG codons mediate translational control of GCN4

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The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

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Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

1989 • 328 citations

mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor.

1993 • 307 citations

Yap, a Novel Family of Eight bZIP Proteins in Saccharomyces cerevisiae with Distinct Biological Functions

1997 • 302 citations

Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon.

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The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression

1987 • 259 citations

5' untranslated sequences are required for the translational control of a yeast regulatory gene.

1984 • 257 citations

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

1991 • 243 citations

Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4

1988 • 237 citations

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Yeast bZip proteins mediate pleiotropic drug and metal resistance.

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1996 • 168 citations

7 Translational Control of GCN4: Gene-specific Regulation by Phosphorylation of elF2

1996 • 143 citations

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Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA

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Identification and Comparison of Stable and Unstable mRNAs in Saccharomyces cerevisiae

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The Relationship between Eukaryotic Translation and mRNA Stability

1995 • 118 citations

Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control

1994 • 115 citations

Polypeptide chain release factors

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1996 • 99 citations

The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability

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Stress-induced transcriptional activation mediated by YAP1 and YAP2 genes that encode the Jun family of transcriptional activators in Saccharomyces cerevisiae

1994 • 95 citations

Saccharomyces cerevisiae exhibits a yAP-1-mediated adaptive response to malondialdehyde

1997 • 86 citations

Overexpression of YAP2, coding for a new yAP protein, and YAP1 in Saccharomyces cerevisiae alleviates growth inhibition caused by 1,10-phenanthroline.

1993 • 83 citations

Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: the roles of the stability and position of stem‐loops in the mRNA leader

1993 • 77 citations

The SNQ3 gene of Saccharomyces cerevisiae confers hyper-resistance to several functionally unrelated chemicals

1991 • 76 citations

Identification and characterization of a Saccharomyces cerevisiae gene (PAR1) conferring resistance to iron chelators

1991 • 76 citations

Protein Synthesis and Targeting in Yeast

1993 • 70 citations

Role of an upstream open reading frame in mediating arginine-specific translational control in Neurospora crassa

1996 • 69 citations

mRNA sequences influencing translation and the selection of AUG initiator codons in the yeast Saccharomyces cerevisiae

1996 • 61 citations

6 Translational Control Mediated by Upstream AUG Codons

1996 • 53 citations

Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay.

1996 • 49 citations

Disruption of Ribosomal Scanning on the 5′-Untranslated Region, and Not Restriction of Translational Initiation per se, Modulates the Stability of Nonaberrant mRNAs in the Yeast Saccharomyces cerevisiae

1997 • 48 citations

Functional Mapping of the Translation-Dependent Instability Element of Yeast MATα1 mRNA

1996 • 40 citations

Translationaj repression by the human iron-regulatory factor (IRF) in Saccharomyces cerevisiae

1993 • 39 citations

The Upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation

1998 • 37 citations

Identification of the cis-acting sequences and trans-acting factors involved in nonsense-mediated mRNA decay

1993 • 32 citations

Effects of cadmium and of YAP1 and CAD1/YAP2 genes on iron metabolism in the yeast Saccharomyces cerevisiae

1995 • 30 citations

Isolation and characterization of additional genes influencing resistance to various mutagens in the yeast Saccharomyces cerevisiae

1992 • 27 citations