Role of Cdc42p in Pheromone-Stimulated Signal Transduction in Saccharomyces cerevisiae

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Current protocols in molecular biology

1988 • 4,543 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Signaling—2000 and Beyond

2000 • 2,544 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

Guide to yeast genetics and molecular biology

1992 • 1,032 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

1990 • 605 citations

An essential G1 function for cyclin-like proteins in yeast

1989 • 574 citations

Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade

1996 • 571 citations

Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins.

1993 • 509 citations

Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae.

1991 • 442 citations

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.

1987 • 439 citations

The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.

1992 • 427 citations

RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA.

1983 • 415 citations

PAK to the future

1999 • 391 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

Methods in enzymology vol 194 guide to yeast genetics and molecular biology

1991 • 359 citations

Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae.

1996 • 353 citations

A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

1998 • 325 citations

The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes

1998 • 279 citations

A cell cycle checkpoint monitors cell morphogenesis in budding yeast.

1995 • 267 citations

Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.

1996 • 248 citations

Identification of a Central Phosphorylation Site in p21-activated Kinase Regulating Autoinhibition and Kinase Activity

1999 • 245 citations

Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway

1998 • 241 citations

Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases

1998 • 223 citations

Pheromone signalling and polarized morphogenesis in yeast

1997 • 221 citations

A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains

1992 • 219 citations

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway

1995 • 209 citations

Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin

1995 • 209 citations

Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase

1997 • 207 citations

Two Genes Required for Cell Fusion During Yeast Conjugation: Evidence for a Pheromone-Induced Surface Protein

1987 • 205 citations

Mutational analysis of CDC42Sc, a Saccharomyces cerevisiae gene that encodes a putative GTP-binding protein involved in the control of cell polarity.

1991 • 204 citations

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

1990 • 204 citations

Pheromone Signalling in Saccharomyces cerevisiae Requires the Small GTP-Binding Protein Cdc42p and Its Activator CDC24

1995 • 192 citations

Phagocytic killing of Candida albicans by different murine effector cells.

1983 • 180 citations

Establishment of Cell Polarity in Yeast

1995 • 176 citations

Association of the Yeast Pheromone Response G Protein βγ Subunits with the Map Kinase Scaffold Ste5p

1995 • 173 citations

Use of a Screen for Synthetic Lethal and Multicopy Suppressee Mutants To Identify Two New Genes Involved in Morphogenesis in Saccharomyces cerevisiae

1991 • 166 citations

Signal Propagation and Regulation in the Mating Pheromone Response Pathway of the Yeast Saccharomyces cerevisiae

1994 • 157 citations

Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae.

1990 • 145 citations

A GTP-exchange factor required for cell orientation

1998 • 136 citations

Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.

1995 • 134 citations

The Complete Set of Predicted Genes from Saccharomyces cerevisiae in a Readily Usable Form

1997 • 124 citations

Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11.

1994 • 122 citations

G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle.

1994 • 119 citations

Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations.

1990 • 110 citations

Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11

1998 • 110 citations

Cla4p, a Saccharomyces cerevisiae Cdc42p-Activated Kinase Involved in Cytokinesis, Is Activated at Mitosis†

1997 • 110 citations

Genetic Evidence for Pak1 Autoinhibition and Its Release by Cdc42

1999 • 98 citations

The SH3-Domain Protein Bem1 Coordinates Mitogen-Activated Protein Kinase Cascade Activation with Cell Cycle Control in Saccharomyces cerevisiae

1996 • 97 citations

Flow cytometric analysis of DNA content in budding yeast

1997 • 96 citations

Functions and Functional Domains of the GTPase Cdc42p

2000 • 85 citations

Mutational Analysis of CDC42Sc, a Saccharomyces cerevisiae Gene That Encodes a Putative GTP-Binding Protein Involved in the Control of Cell Polarity

1991 • 74 citations

AKR1 Encodes a Candidate Effector of the Gβγ Complex in the Saccharomyces cerevisiae Pheromone Response Pathway and Contributes to Control of both Cell Shape and Signal Transduction

1996 • 63 citations

Preliminary characterization of the transcriptional and translational products of the Saccharomyces cerevisiae cell division cycle gene CDC28.

1982 • 59 citations

Interactions between the Ankyrin Repeat-Containing Protein Akr1p and the Pheromone Response Pathway in Saccharomyces cerevisiae

1996 • 53 citations

Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity

1996 • 25 citations

Preliminary Characterization of the Transcriptional and Translational Products of the Saccharomyces cerevisiae Cell Division Cycle Gene CDC28

1982 • 25 citations

The Role of Cdc42 in Signal Transduction and Mating of the Budding Yeast Saccharomyces cerevisiae

1998 • 22 citations