Comparative genomic analysis of the Tribolium immune system

Amino acid substitution matrices from protein blocks.

1992 • 5,998 citations

CAP3: A DNA Sequence Assembly Program

1999 • 5,180 citations

Multiple sequence alignment with the Clustal series of programs

2003 • 4,849 citations

The Host Defense of Drosophila melanogaster

2007 • 3,004 citations

Insect hemocytes and their role in immunity

2002 • 1,517 citations

The Role of Hemocytes in <b><i>Anopheles gambiae</i></b> Antiplasmodial Immunity

2013 • 1,046 citations

Anti‐microbial peptides: from invertebrates to vertebrates

2004 • 1,042 citations

Immune pathways and defence mechanisms in honey bees Apis mellifera

2006 • 943 citations

LPS, TLR4 and infectious disease diversity

2004 • 935 citations

Immunity-Related Genes and Gene Families in Anopheles gambiae

2002 • 906 citations

Recent Advances in the Innate Immunity of Invertebrate Animals

2005 • 744 citations

Innate immune responses of a lepidopteran insect, Manduca sexta

2004 • 635 citations

Melanogenesis and associated cytotoxic reactions: Applications to insect innate immunity

2005 • 611 citations

Drosophila immunity: paths and patterns

2003 • 584 citations

Anopheles gambiae Immune Responses to Human and Rodent Plasmodium Parasite Species

2006 • 415 citations

Serine proteinase inhibitors in arthropod immunity

1999 • 412 citations

The clip-domain family of serine proteinases in arthropods

2000 • 370 citations

Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning

2005 • 367 citations

Reconstructing immune phylogeny: new perspectives

2005 • 348 citations

Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease

2002 • 343 citations

The roles of JAK/STAT signaling in Drosophila immune responses

2004 • 334 citations

A Scavenger Function for a DrosophilaPeptidoglycan Recognition Protein

2003 • 326 citations

Nimrod, a Putative Phagocytosis Receptor with EGF Repeats in Drosophila Plasmatocytes

2007 • 318 citations

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

2003 • 308 citations

A Spätzle-Processing Enzyme Required for Toll Signaling Activation in Drosophila Innate Immunity

2006 • 284 citations

Immulectin-2, a Lipopolysaccharide-specific Lectin from an Insect, Manduca sexta, Is Induced in Response to Gram-negative Bacteria

2000 • 279 citations

Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants ofDrosophila

2000 • 277 citations

Drosophila Hemopoiesis and Cellular Immunity

2007 • 276 citations

A Role for Insect Galectins in Parasite Survival

2004 • 255 citations

Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae

2004 • 245 citations

C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway

1999 • 238 citations

‘Trans-generational immune priming’: specific enhancement of the antimicrobial immune response in the mealworm beetle,Tenebrio molitor

2006 • 236 citations

Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen

1999 • 222 citations

Host-pathogen interactions in drosophila: new tricks from an old friend

2006 • 217 citations

Beepath: An ordered quantitative-PCR array for exploring honey bee immunity and disease

2006 • 216 citations

Peptidoglycan recognition proteins: on and off switches for innate immunity

2004 • 204 citations

Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster

2003 • 203 citations

A Pattern-recognition Protein for β-1,3-Glucan

2000 • 201 citations

Two Proteases Defining a Melanization Cascade in the Immune System of Drosophila

2006 • 200 citations

INSECT HEMOCYTES AND THEIR ROLE IN IMMUNITY

2008 • 192 citations

Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family.

1991 • 190 citations

Comparative analysis of serine protease‐related genes in the honey bee genome: possible involvement in embryonic development and innate immunity

2006 • 182 citations

The lipopolysaccharide‐binding protein participating in hemocyte nodule formation in the silkworm Bombyx mori is a novel member of the C‐type lectin superfamily with two different tandem carbohydrate‐recognition domains¹

1999 • 180 citations

A masquerade-like serine proteinase homologue is necessary for phenoloxidase activity in the coleopteran insect, Holotrichia diomphalia larvae

2000 • 161 citations

Increased male fertility in Tribolium confusum beetles after infection with the intracellular parasite Wolbachia

1995 • 143 citations

A New Easter-type Serine Protease Cleaves a Masquerade-like Protein during Prophenoloxidase Activation in Holotrichia diomphalia Larvae

2002 • 140 citations

β-1,3-Glucan recognition protein-2 (βGRP-2) from Manduca sexta: an acute-phase protein that binds β-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase activation

2003 • 132 citations

In vitro activation of pro‐phenol‐oxidase by two kinds of pro‐phenol‐oxidase‐activating factors isolated from hemolymph of coleopteran, Holotrichia diomphalia larvae

1998 • 129 citations

Reactive oxygen species detoxification by catalase is a major determinant of fecundity in the mosquito Anopheles gambiae

2007 • 123 citations

Mouse SWAM1 and SWAM2 Are Antibacterial Proteins Composed of a Single Whey Acidic Protein Motif

2003 • 116 citations

Emergence and Disappearance of an Immune Molecule, an Antimicrobial Lectin, in Basal Metazoa

2003 • 108 citations

Primitive complement system—recognition and activation

2004 • 104 citations

Expression and Evolution of the Drosophila Attacin/Diptericin Gene Family

2000 • 103 citations

Interaction of β-1,3-Glucan with Its Recognition Protein Activates Hemolymph Proteinase 14, an Initiation Enzyme of the Prophenoloxidase Activation System in Manduca sexta

2006 • 102 citations

Pathogen recognition and signalling in the Drosophila innate immune response

2006 • 94 citations

Angiopoietins and Angiopoietin-Like Proteins in Angiogenesis

2006 • 91 citations

Participation of a galactose-specific C-type lectin inDrosophilaimmunity

2006 • 83 citations

Determinants of virulence for the parasite Nosema whitei in its host Tribolium castaneum

2005 • 73 citations

Solution Structure of Alo-3: A New Knottin-Type Antifungal Peptide from the Insect Acrocinus longimanus

2003 • 68 citations

Rates of DNA change and phylogeny from the DNA sequences of the alcohol dehydrogenase gene for five closely related species of Hawaiian Drosophila.

1991 • 62 citations

A novel lectin with a fibrinogen‐like domain and its potential involvement in the innate immune response of Armigeres subalbatus against bacteria

2004 • 61 citations

A Novel 43-kDa Protein as a Negative Regulatory Component of Phenoloxidase-induced Melanin Synthesis

2005 • 60 citations

Beetling around the genome

2003 • 56 citations

Ookinete-induced midgut peroxidases detonate the time bomb in anopheline mosquitoes

2005 • 44 citations

Costly Resistance to Parasitism

2005 • 41 citations

Purification and cDNA cloning of a cecropin from the longicorn beetle, Acalolepta luxuriosa

2005 • 37 citations

Characterization of a homologue of the Rel/NF-κB transcription factor from a beetle, Allomyrina dichotoma

2004 • 22 citations

Delta activity independent of its activity as a ligand of Notch

2005 • 20 citations