Ookinete-induced midgut peroxidases detonate the time bomb in anopheline mosquitoes

Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite

1997 • 778 citations

Peroxynitrite reactivity with amino acids and proteins

2003 • 545 citations

A Tale of Two Controversies

2002 • 484 citations

Nitric oxide and its role in apoptosis

1998 • 444 citations

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

1996 • 407 citations

The mosquitoAnopheles stephensilimits malaria parasite development with inducible synthesis of nitric oxide

1998 • 394 citations

The regulatory role of nitric oxide in apoptosis

2001 • 384 citations

Molecular interactions between Anopheles stephensi midgut cells and Plasmodium berghei: the time bomb theory of ookinete invasion of mosquitoes

2000 • 375 citations

Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites

1997 • 373 citations

Genome expression analysis of Anopheles gambiae : Responses to injury, bacterial challenge, and malaria infection

2002 • 279 citations

Malaria infection of the mosquitoAnopheles gambiaeactivates immune-responsive genes during critical transition stages of the parasite life cycle

1998 • 271 citations

Mechanism of Reaction of Myeloperoxidase with Nitrite

2000 • 221 citations

Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils

1996 • 210 citations

Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori.

1996 • 209 citations

Plasmodium activates the innate immune response of Anopheles gambiae mosquitoes

1997 • 194 citations

Novel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus

1994 • 183 citations

Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases

2002 • 170 citations

Protein Tyrosine Nitration in Cytokine-activated Murine Macrophages

2001 • 154 citations

Nitric oxide induces tyrosine nitration and release of cytochromecpreceding an increase of mitochondrial transmembrane potential in macrophages

1999 • 135 citations

The Role of Reactive Nitrogen Species in Secondary Spinal Cord Injury

2000 • 134 citations

Inducible Peroxidases Mediate Nitration of Anopheles Midgut Cells Undergoing Apoptosis in Response to Plasmodium Invasion

2004 • 126 citations

Nitration and inactivation of cytochrome P450_BM‐3 by peroxynitrite

2000 • 91 citations

In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation

2001 • 88 citations

Activity of Class III Peroxidases in the Defense of Cotton to Bacterial Blight

2003 • 88 citations

The RsmA^-Mutants ofErwinia carotovorasubsp.carotovoraStrain Ecc71 OverexpresshrpN_ECCand Elicit a Hypersensitive Reaction-like Response in Tobacco Leaves

1996 • 83 citations

Implications of Time Bomb model of ookinete invasion of midgut cells

2002 • 77 citations

Site-Selective Nitration of Tyrosine in Human Serum Albumin by Peroxynitrite

2001 • 73 citations

Bactericidal Activity of Human Eosinophilic Granulocytes againstEscherichia coli

2001 • 67 citations

Differential Expression of Peroxidase Isogenes During the Early Stages of Infection of the Tropical Forage LegumeStylosanthes humilisbyColletotrichum gloeosporioides

1995 • 66 citations

Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.

2001 • 66 citations

Mechanistic insight into the peroxidase catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide

2004 • 63 citations

T. cruzi: sensitization to macrophage killing by eosinophil peroxidase.

1982 • 59 citations

Arming of mononuclear phagocytes by eosinophil peroxidase bound to Staphylococcus aureus.

1982 • 59 citations

Auto-protective redox buffering systems in stimulated macrophages.

2002 • 59 citations

The killing of newborn larvae of Trichinella spiralis by eosinophil peroxidase in vitro

1981 • 58 citations

Candidacidal activity of myeloperoxidase: mechanisms of inhibitory influence of soluble cell wall mannan

1983 • 54 citations

Two pathogen-responsive genes in parsley encode a tyrosine-rich hydroxyproline-rich glycoprotein (hrgp) and an anionic peroxidase

1995 • 51 citations

Differential expression of 10 sweetpotato peroxidase genes in response to bacterial pathogen, Pectobacterium chrysanthemi

2004 • 48 citations

Nitrogen Dioxide Induces Death in Lung Epithelial Cells in a Density-Dependent Manner

2001 • 47 citations

Sodium Nitroprusside-Induced Mitochondrial Apoptotic Events in Insulin-Secreting RINm5F Cells Are Associated with MAP Kinases Activation

2001 • 41 citations

Retardation of early-onset PMA-induced apoptosis in mouse neutrophils deficient in myeloperoxidase

2001 • 33 citations

Nitric oxide induces murine thymocyte apoptosis by oxidative injury and a p53-dependent mechanism

2001 • 33 citations

Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid

2002 • 32 citations

Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite . Stopped-flow measurements prove ferryl intermediates

2000 • 25 citations

Effects of nitric oxide on the eosinophil survival in vitro. A role for nitrosyl‐heme

1999 • 21 citations

Eosinophil peroxidase catalyzes JNK-mediated membrane blebbing in a Rho kinase-dependent manner

2003 • 19 citations