Herpes Simplex Virus Inhibits Apoptosis through the Action of Two Genes, Us5 and Us3

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Protease activation during apoptosis: Death by a thousand cuts?

1995 • 1,335 citations

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 • 1,305 citations

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

1997 • 1,207 citations

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

Regulation of apoptosis by viral gene products

1997 • 639 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

Chapter 9 The End of the (Cell) Line: Methods for the Study of Apoptosis in Vitro

1995 • 569 citations

Ultraviolet Light Induces Apoptosis via Direct Activation of CD95 (Fas/APO-1) Independently of Its Ligand CD95L

1998 • 472 citations

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1997 • 433 citations

Programmed Cell Death in Bacterial Populations

1995 • 333 citations

Ultraviolet Radiation-induced Apoptosis Is Mediated by Activation of CD-95 (Fas/APO-1)

1997 • 298 citations

The herpes simplex virus 1 protein kinase U _S 3 is required for protection from apoptosis induced by the virus

1997 • 271 citations

An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ

1994 • 247 citations

FLIP Prevents Apoptosis Induced by Death Receptors But Not by Perforin/Granzyme B, Chemotherapeutic Drugs, and Gamma Irradiation

1998 • 247 citations

Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner

1998 • 245 citations

Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture

1987 • 192 citations

The Herpes Simplex Virus Type 1 Regulatory Protein ICP27 Is Required for the Prevention of Apoptosis in Infected Human Cells

1999 • 188 citations

Differential Regulation of the p21/WAF-1 and mdm2 Genes after High-Dose UV Irradiation: p53-Dependent and p53-Independent Regulation of the mdm2 Gene

1997 • 172 citations

Resistance of cultured peripheral T cells towards activation‐induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death‐inducing signaling complex

1997 • 172 citations

Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells

1997 • 128 citations

Analysis of the contributions of herpes simplex virus type 1 membrane proteins to the induction of cell-cell fusion

1994 • 116 citations

Herpes Simplex Virus Type 1 Renders Infected Cells Resistant to Cytotoxic T-Lymphocyte-Induced Apoptosis

1998 • 112 citations

Role of p53 in UVB-Induced Apoptosis in Human HaCaT Keratinocytes

1997 • 94 citations

Evolutionary relationships of virion glycoprotein genes in the S regions of alphaherpesvirus genomes

1990 • 91 citations

Herpes Simplex Virus 1 Blocks Caspase-3-Independent and Caspase-Dependent Pathways to Cell Death

1999 • 89 citations

Apoptosis regulators from DNA viruses

1998 • 87 citations

Bacterial Viruses: Bacterial altruism?

1994 • 50 citations

Active oxygen species mediate the solar ultraviolet radiation‐dependent increase in the tumour suppressor protein p53 in human skin fibroblasts

1997 • 49 citations

The US5 Open Reading Frame of Herpes simplex Virus Type 1 Does Encode a Glycoprotein (gJ)

1998 • 30 citations

How Do CTL Control Virus Infections? Evidence for Prelytic Halt of Herpes simplex

1992 • 26 citations

Apoptosis of cord blood T lymphocytes by herpes simplex virus type 1.

1997 • 24 citations

Fas-Based T Cell-Mediated Cytotoxicity

1995 • 20 citations