Monitoring mRNA Decapping Activity

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

1993 • 660 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

Degradation of mRNA in eukaryotes

1995 • 648 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

5'-terminal cap structure in eucaryotic messenger ribonucleic acids

1980 • 463 citations

Premature translational termination triggers mRNA decapping

1994 • 399 citations

Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure.

1993 • 378 citations

Life and death in the cytoplasm: messages from the 3′ end

1997 • 335 citations

An essential component of the decapping enzyme required for normal rates of mRNA turnover

1996 • 328 citations

Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae

1996 • 246 citations

Mutations affecting stability and deadenylation of the yeast MFA2 transcript.

1992 • 228 citations

Regulation of mRNA turnover in eukaryotic cells.

1991 • 171 citations

Mutations in trans-Acting Factors Affecting mRNA Decapping in Saccharomyces cerevisiae

1996 • 168 citations

Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme

1998 • 160 citations

Characterization of cis-Acting Sequences and Decay Intermediates Involved in Nonsense-Mediated mRNA Turnover

1995 • 146 citations

5′-Exonuclease-2 of Saccharomyces cerevisiae

1995 • 118 citations

Catalytic activity of vaccinia mRNA capping enzyme subunits coexpressed in Escherichia coli.

1990 • 98 citations

Enzyme cleaving the 5′‐terminal methylated blocked structure of messenger RNA

1976 • 70 citations

Stability of Maternal mRNA in Xenopus Embryos: Role of Transcription and Translation

1990 • 65 citations

mRNA-decapping enzyme from Saccharomyces cerevisiae: purification and unique specificity for long RNA chains.

1988 • 58 citations

Stability of maternal mRNA in Xenopus embryos: role of transcription and translation.

1990 • 53 citations

His-154 is involved in the linkage of the Saccharomyces cerevisiae L-A double-stranded RNA virus Gag protein to the cap structure of mRNAs and is essential for M1 satellite virus expression.

1994 • 50 citations

Characterization of the m7G(5')pppN-pyrophosphatase activity from HeLa cells.

1977 • 45 citations

Very long-lived messenger RNA in ovaries of Xenopus laevis

1977 • 42 citations

An mRNA decapping enzyme from ribosomes of Saccharomyces cerevisiae

1980 • 32 citations

Novel activity of potato nucleotide pyrophosphatase

1976 • 30 citations

Maternal mRNA Expression in Early Development: Regulation at the 3' End

1990 • 11 citations