Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

The Cell Biology of Macrophage Activation

1984 • 1,623 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1987 • 648 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1991 • 471 citations

Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.

1984 • 405 citations

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn)

1991 • 395 citations

The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1989 • 362 citations

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages.

1991 • 318 citations

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.

1987 • 278 citations

Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes.

1988 • 278 citations

Molecular Transductional Mechanisms by which IFNγ and Other Signals Regulate Macrophage Development

1987 • 266 citations

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.

1987 • 253 citations

Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5

1987 • 209 citations

Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus.

1991 • 165 citations

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn.

1992 • 151 citations

Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation.

1986 • 118 citations

Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages.

1992 • 115 citations

The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line

1986 • 113 citations

Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck).

1989 • 112 citations

src-related tyrosine protein kinases as signaling components in hematopoietic cells.

1990 • 109 citations

Augmented expression of a myeloid-specific protein tyrosine kinase gene (hck) after macrophage activation.

1988 • 102 citations

Specialized protein tyrosine kinase proto-oncogenes in hematopoietic cells

1989 • 99 citations

The generation of macrophage-like cell lines by transfection with SV40 origin defective DNA.

1984 • 75 citations

Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells.

1987 • 68 citations

Identification of a Human Gene (HCK) that Encodes a Protein-Tyrosine Kinase and is Expressed in Hemopoietic Cells

1987 • 63 citations

Novel Protein-Tyrosine Kinase Gene (hck) Preferentially Expressed in Cells of Hematopoietic Origin

1987 • 62 citations

Transformation of NIH 3T3 fibroblasts by an activated form of p59hck.

1989 • 42 citations

Hematopoietic Cells Express Two Forms of lyn Kinase Differing by 21 Amino Acids in the Amino Terminus

1991 • 39 citations

Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic cells.

1989 • 36 citations

Human protein-tyrosine kinase gene HCK: expression and structural analysis of the promoter region.

1992 • 28 citations