Avian retroviral RNA element promotes unspliced RNA accumulation in the cytoplasm

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1995 • 1,127 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

1986 • 673 citations

A second post-transcriptional trans-activator gene required for HTLV-III replication

1986 • 639 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

A small element from the Mason-Pfizer monkey virusgenome makes human immunodeficiency virus type 1 expression and replicationRev-independent.

1994 • 425 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.

1988 • 355 citations

Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product

1980 • 324 citations

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

1995 • 308 citations

The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm.

1994 • 305 citations

Using PCR to Engineer DNA

1989 • 303 citations

Mechanism of action of regulatory proteins encoded by complex retroviruses

1992 • 299 citations

Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein

1992 • 276 citations

A human nucleoporin-like protein that specifically interacts with HIV Rev

1995 • 268 citations

Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs.

1991 • 232 citations

Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast

1995 • 223 citations

The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs.

1992 • 208 citations

Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes.

1993 • 188 citations

Rous sarcoma virus nucleic acid-binding protein p12 is necessary for viral 70S RNA dimer formation and packaging

1986 • 187 citations

Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles

1990 • 184 citations

Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes

1994 • 178 citations

Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation

1991 • 168 citations

Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression

1991 • 160 citations

DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src

1982 • 152 citations

HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression.

1995 • 149 citations

Control of retroviral RNA splicing through maintenance of suboptimal processing signals.

1990 • 141 citations

Regulation of Rous sarcoma virus RNA splicing and stability.

1988 • 137 citations

Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein

1990 • 130 citations

Presence of Negative and Positive cis-Acting RNA Splicing Elements within and Flanking the First tat Coding Exon of Human Immunodeficiency Virus Type 1

1994 • 130 citations

Hepatitis B virus RNA element that facilitates accumulation of surface gene transcripts in the cytoplasm

1994 • 113 citations

cis-Acting RNA packaging locus in the 115-nucleotide direct repeat of Rous sarcoma virus

1983 • 112 citations

The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.

1991 • 112 citations

Specificity of retroviral RNA packaging

1991 • 108 citations

Two Strong 5′ Splice Sites and Competing, Suboptimal 3′ Splice Sites Involved in Alternative Splicing of Human Immunodeficiency Virus Type 1 RNA

1995 • 103 citations

The basic domain of Rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6.U5 small nuclear ribonucleoprotein in spliceosome assembly

1993 • 102 citations

Nucleotide sequence of noncoding regions in Rous-associated virus-2: comparisons delineate conserved regions important in replication and oncogenesis

1984 • 101 citations

Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus

1980 • 99 citations

The tat/rev intron of human immunodeficiency virus type 1 is inefficiently spliced because of suboptimal signals in the 3' splice site

1994 • 99 citations

The Rev Protein of Human Immunodeficiency Virus Type 1 Promotes Polysomal Association and Translation of gag/pol and vpu/env mRNAs

1992 • 89 citations

HIV-1 Rev Is Capable of Shuttling between the Nucleus and Cytoplasm

1994 • 84 citations

Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing

1991 • 79 citations

Mutation of an RSV intronic element abolishes both U11/U12 snRNP binding and negative regulation of splicing.

1993 • 78 citations

Rev and the Fate of Pre-mRNA in the Nucleus: Implications for the Regulation of RNA Processing in Eukaryotes

1993 • 78 citations

Control of Retroviral RNA Splicing through Maintenance of Suboptimal Processing Signals

1990 • 75 citations

Regulation of Rous Sarcoma Virus RNA Splicing and Stability

1988 • 73 citations

Nonsense codons within the Rous sarcoma virus gag gene decrease the stability of unspliced viral RNA.

1991 • 72 citations

Intronic sequences and 3' splice sites control Rous sarcoma virus RNA splicing

1992 • 71 citations

Sequence comparison in the crossover region of an oncogenic avian retrovirus recombinant and its nononcogenic parent: genetic regions that control growth rate and oncogenic potential.

1982 • 69 citations

Inhibition of methylation at two internal N6-methyladenosine sites caused by GAC to GAU mutations.

1987 • 56 citations

Synthesis and Processing of Avian Sarcoma Retrovirus RNA

1988 • 52 citations

A Suboptimal src 3′ Splice Site Is Necessary for Efficient Replication of Rous Sarcoma Virus

1995 • 45 citations

Rous sarcoma virus RNA stability requires an open reading frame in the gag gene and sequences downstream of the gag-pol junction.

1994 • 42 citations

Molecular biology of HIV-1

1992 • 41 citations

Production of avian leukosis virus particles in mammalian cells can be mediated by the interaction of the human immunodeficiency virus protein Rev and the Rev-responsive element.

1995 • 35 citations

Sequence Comparison in the Crossover Region of an Oncogenic Avian Retrovirus Recombinant and Its Nononcogenic Parent: Genetic Regions That Control Growth Rate and Oncogenic Potential

1982 • 34 citations

Chapter 2 Isolation of Nuclei from Animal Cells in Culture

1978 • 32 citations

Nonsense Codons within the Rous Sarcoma Virus gag Gene Decrease the Stability of Unspliced Viral RNA

1991 • 32 citations

Stabilities of Avian Sarcoma Virus RNAs: Comparison of Subgenomic and Genomic Species with Cellular mRNAs

1983 • 25 citations

Rous Sarcoma Virus RNA Stability Requires an Open Reading Frame in the gag Gene and Sequences Downstream of the gag-pol Junction

1994 • 22 citations

In vivo binding of wild-type and mutant human immunodeficiency virus type 1 Rev proteins: implications for function

1992 • 22 citations

Studies on the Topography of the Catalytic Site of Acetylcholinesterase Using Polyclonal and Monoclonal Antibodies

1990 • 21 citations

Comparison of the structural organizations in the 3′-terminal regions of five avian retrovirus strains: RAV 7, RAV 50, 1377, PR-B, and SR-B

1987 • 8 citations