HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Nucleotide sequence of the AIDS virus, LAV

1985 • 1,225 citations

A New Subtype of Human T-Cell Leukemia Virus (HTLV-II) Associated with a T-Cell Variant of Hairy Cell Leukemia

1982 • 1,195 citations

Antibodies Reactive with Human T-Lymphotropic Retroviruses (HTLV-III) in the Serum of Patients with AIDS

1984 • 1,163 citations

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

1986 • 1,032 citations

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

1984 • 976 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

Trans -Activator Gene of Human T-Lymphotropic Virus Type III (HTLV-III)

1985 • 872 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.

1986 • 740 citations

Nucleotide Sequence and Expression of an AIDS-Associated Retrovirus (ARV-2)

1985 • 718 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

A second post-transcriptional trans-activator gene required for HTLV-III replication

1986 • 639 citations

Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency Syndrome

1984 • 639 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

Human T-lymphotropic retroviruses

1985 • 623 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus

1985 • 572 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

The pX Protein of HTLV-I Is a Transcriptional Activator of Its Long Terminal Repeats

1985 • 514 citations

Trans -Acting Transcriptional Regulation of Human T-Cell Leukemia Virus Type III Long Terminal Repeat

1985 • 500 citations

Characterization of gp41 as the Transmembrane Protein Coded by the HTLV-III/LAV Envelope Gene

1985 • 442 citations

Sequence Homology and Morphologic Similarity of HTLV-III and Visna Virus, a Pathogenic Lentivirus

1985 • 407 citations

A Transcriptional Activator Protein Encoded by the x- lor Region of the Human T-Cell Leukemia Virus

1985 • 346 citations

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

1986 • 325 citations

Slow, persistent replication of lentiviruses: role of tissue macrophages and macrophage precursors in bone marrow.

1985 • 320 citations

Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene

1985 • 314 citations

Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing

1981 • 261 citations

Expression of the HTLV-III envelope gene by a recombinant vaccinia virus

1986 • 240 citations

Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation

1985 • 215 citations

The x Gene Is Essential for HTLV Replication

1985 • 161 citations

Trans-Activator Gene of HTLV-II Induces IL-2 Receptor and IL-2 Cellular Gene Expression

1986 • 129 citations

A New HTLV-III/LAV Protein Encoded by a Gene Found in Cytopathic Retroviruses

1986 • 127 citations

Identification of HTLV-III/LAV sor Gene Product and Detection of Antibodies in Human Sera

1986 • 119 citations

Transactivation induced by human T-lymphotropic virus type III (HTLV III) maps to a viral sequence encoding 58 amino acids and lacks tissue specificity

1986 • 117 citations

Three novel genes of human T-lymphotropic virus type III: immune reactivity of their products with sera from acquired immune deficiency syndrome patients.

1986 • 113 citations

Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro.

1986 • 90 citations

Monoclonal antibodies specific for p24, the major core protein of human T-cell leukemia virus type III.

1985 • 76 citations

Transcription of Novel Open Reading Frames of AIDS Retrovirus During Infection of Lymphocytes

1985 • 64 citations

Role of intron-contained sequences in formation of moloney murine leukemia virus env mRNA.

1984 • 62 citations

Insertion of several different DNAs in reticuloendotheliosis virus strain T suppresses transformation by reducing the amount of subgenomic mRNA

1986 • 53 citations

Methylation of human T-cell leukemia virus proviral DNA and viral RNA expression in short- and long-term cultures of infected cells

1984 • 39 citations

Journey to adulthood

1985 • 3 citations