Activated non-neural specific T cells open the blood–brain barrier to circulating antibodies

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein.

1988 • 721 citations

A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structure.

1993 • 500 citations

Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis

1993 • 400 citations

SERIAL GADOLINIUM ENHANCED MAGNETIC RESONANCE IMAGING IN MULTIPLE SCLEROSIS

1988 • 397 citations

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases.

1994 • 338 citations

The neuropathology of multiple sclerosis.

2000 • 332 citations

A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody

1984 • 318 citations

TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase

1992 • 282 citations

Animal models

1994 • 276 citations

Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study

1993 • 264 citations

Sequence Homology Between Certain Viral Proteins and Proteins Related to Encephalomyelitis and Neuritis

1985 • 243 citations

DURATION AND SELECTIVITY OF BLOOD-BRAIN BARRIER BREAKDOWN IN CHRONIC RELAPSING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS STUDIED BY GADOLINIUM-DTPA AND PROTEIN MARKERS

1990 • 215 citations

Heterogeneity of blood‐brain barrier changes in multiple sclerosis

1990 • 201 citations

Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia.

1994 • 186 citations

Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis.

1989 • 85 citations

Sites of egress of inflammatory cells and horseradish peroxidase transport across the blood-brain barrier in a murine model of chronic relapsing experimental allergic encephalomyelitis

1989 • 84 citations

Intraneural activated T cells cause focal breakdown of the blood-nerve barrier

1995 • 74 citations

Mechanisms of edema formation in experimental autoimmune encephalomyelitis. The contribution of inflammatory cells.

1990 • 65 citations

Pattern of schwann cell remyelination in a spinal cord lesion

1984 • 18 citations