Mesolimbic Dopamine D3 Receptors and Use of Antipsychotics in Patients With Schizophrenia

Functional architecture of basal ganglia circuits: neural substrates of parallel processing

1990 • 4,029 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised

1988 • 1,038 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

Dopamine D4 receptors elevated in schizophrenia

1993 • 632 citations

Acute Effects of Typical and Atypical Antipsychotic Drugs on the Release of Dopamine from Prefrontal Cortex, Nucleus Accumbens, and Striatum of the Rat: An In Vivo Microdialysis Study

1990 • 407 citations

Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor

1992 • 402 citations

Increased Brain Dopamine and Dopamine Receptors in Schizophrenia

1982 • 393 citations

Localization of dopamine D3 receptors to mesolimbic and D2 receptors to mesostriatal regions of human forebrain.

1994 • 326 citations

Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases

1987 • 322 citations

Dopaminergic Mechanisms in Idiopathic and Drug-induced Psychoses

1990 • 279 citations

Dopamine Receptor mRNA Expression in Human Striatum and Neocortex

1996 • 277 citations

A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons.

1995 • 183 citations

Organization of dopamine D1 and D2 receptors in human striatum: Receptor autoradiographic studies in Huntington's disease and schizophrenia

1988 • 170 citations

Chapter 14 Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system

1993 • 140 citations

Limbic/mesolimbic connections and the pathogenesis of schizophrenia

1991 • 123 citations

The dopamine hypothesis of schizophrenia: limbic interactions with serotonin and norepinephrine

1993 • 113 citations

Prospective clinicopathologic studies of schizophrenia: accrual and assessment of patients

1995 • 112 citations

Autoradiographic distribution of D3-type dopamine receptors in human brain using [3H]7-hydroxy-N,N-di-n-propyl-2-aminotetralin

1994 • 98 citations

Influence of Dopamine on Limbic Inputs to the Nucleus Accumbens

1988 • 87 citations

Alterations in mRNA levels of D2 receptors and neuropeptides in striatonigral and striatopallidal neurons of rats with neuroleptic‐induced dyskinesias

1994 • 85 citations

Differential effects of clozapine and haloperidol on dopamine receptor mRNA expression in rat striatum and cortex

1996 • 60 citations

D1 and D2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment

1992 • 55 citations

A quantitative method of analyzing the interaction of slightly selective radioligands with multiple receptor subtypes.

1986 • 52 citations

Long-term haloperidol elevates dopamine D4 receptors by 2-fold in rats

1995 • 51 citations

Characterization of [125I](R)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino] tetralin binding to dopamine D3 receptors in rat olfactory tubercle.

1994 • 49 citations

Lateralized interdependence between limbicotemporal and ventrostriatal dopaminergic transmission

1994 • 48 citations

Expression of the Proneurotensin Gene in the Rat Brain and Its Regulation by Antipsychotic Drugsa

1992 • 39 citations

The effect of haloperidol on D2 dopamine receptor subtype mRNA levels in the brain

1994 • 34 citations

Characterization of binding sites for [125I]R(+)trans-7-OH-PIPAT in rat brain

1994 • 27 citations

New selective dopamine D-2 antagonists as antipsychotic agents. Pharmacological, chemical, structural and theoretical considerations.

1987 • 25 citations