Expression of the Proneurotensin Gene in the Rat Brain and Its Regulation by Antipsychotic Drugsa

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

1973 • 1,501 citations

Dopamine receptors and the dopamine hypothesis of schizophrenia

1987 • 867 citations

The Dopamine Hypothesis of Schizophrenia: A Review*

1976 • 862 citations

Drugs, Neurotransmitters, and Schizophrenia

1974 • 832 citations

Neurotensin: Topographical distribution in rat brain by immunohistochemistry

1982 • 538 citations

Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach.

1976 • 537 citations

Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

1989 • 502 citations

Neuroleptics increase C-FOS expression in the forebrain: Contrasting effects of haloperidol and clozapine

1992 • 477 citations

Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons

1984 • 439 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

Neurotensin: immunohistochemical localization in rat central nervous system.

1977 • 341 citations

Neurotensin: perchance an endogenous neuroleptic?

1980 • 272 citations

Distribution of D2 dopamine receptor mRNA in rat brain.

1989 • 263 citations

Regional and subcellular distributions of brain neurotensin

1976 • 237 citations

The rat gene encoding neurotensin and neuromedin N. Structure, tissue-specific expression, and evolution of exon sequences.

1988 • 216 citations

Increase of neurotensin content elicited by neuroleptics in nucleus accumbens.

1980 • 207 citations

CLOZAPINE AND HALOPERIDOL IN A SINGLE‐BLIND CROSS‐OVER TRIAL: THERAPEUTIC AND BIOCHEMICAL ASPECTS IN THE TREATMENT OF SCHIZOPHRENIA

1974 • 198 citations

Reduced dopaminergic binding during aging in the rodent striatum

1980 • 197 citations

The Regional Distribution and Chromatographic Characterisation of Neurotensin‐Like Immunoreactivity in the Rat Central Nervous System

1982 • 192 citations

Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies.

1983 • 184 citations

Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor.

1987 • 181 citations

Subnormal CSF levels of neurotensin in a subgroup of schizophrenic patients: normalization after neuroleptic treatment

1982 • 176 citations

Localization of the mRNA for the dopamine D2 receptor in the rat brain by in situ hybridization histochemistry.

1989 • 167 citations

Induction of c‐fos mRNA Expression in Rat Striatum by Neuroleptic Drugs

1990 • 165 citations

Interactions between neurotensin and dopamine in the brain: An overview

1983 • 151 citations

Dietary Restriction Retards the Age-Associated Loss of Rat Striatal Dopaminergic Receptors

1981 • 138 citations

Neurotensin-dopamine interactions in the CNS

1985 • 133 citations

Distribution of neurotensin/neuromedin N mRNA in rat forebrain: unexpected abundance in hippocampus and subiculum.

1989 • 123 citations

Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum

1992 • 120 citations

Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei

1988 • 102 citations

Mutually dependent response elements in the Cis-regulatory region of the neurotensin/neuromedin N gene integrate environmental stimuli in PC12 cells

1990 • 85 citations

Quantitative autoradiographical analysis of the age-related modulation of central dopamine D1 and D2 receptors

1990 • 82 citations

Effects of acute and long-term treatment with neuroleptics on regional telencephalic neurotensin levels in the male rat

1986 • 78 citations

Cholecystokinin octapeptide levels in rat brain are changed after subchronic neuroleptic treatment

1983 • 77 citations

Effects of dopamine depletion on striatal neurotensin: biochemical and immunohistochemical studies

1989 • 73 citations

Effect of Chronic Typical and Atypical Neuroleptic Treatment on Proenkephalin mRNA Levels in the Striatum and Nucleus Accumbens of the Rat

1990 • 72 citations

Effect of methamphetamine on neurotensin concentrations in rat brain regions.

1987 • 65 citations

Numbers of neurotensin-immunoreactive neurons selectively increased in rat ventral striatum following acute haloperidol administration

1988 • 65 citations

Haloperidol rapidly increases the number of neurotensin mRNA-expressing neurons in neostriatum of the rat brain

1991 • 62 citations

Changes in the limbic neurotensin systems induced by dopaminergic drugs

1988 • 58 citations

Characterization of dopaminergic influence on striatal-nigral neurotensin systems

1987 • 54 citations

Estrogen Induces Neurotensin/Neuromedin N Messenger Ribonucleic Acid in a Preoptic Nucleus Essential for the Preovulatory Surge of Luteinizing Hormone in the Rat*

1989 • 53 citations

Role of dopamine D-1 and D-2 receptors in the regulation of neurotensin systems of the neostriatum and the nucleus accumbens

1989 • 53 citations

Effects of short- and long-term haloperidol administration and withdrawal on regional brain cholecystokinin and neurotensin concentrations in the rat

1989 • 48 citations

Cholecystokinin and neurotensin mRNAs are differentially expressed in subnuclei of the ventral tegmental area

1990 • 43 citations

Differential effects of acute dopaminergic D1 and D2 receptor antagonists on proneurotensin mRNA expression in rat striatum

1991 • 38 citations

The effect of acute haloperidol treatment on brain proneurotensin mRNA: in situ hybridization analyses using a novel fluorescence detection procedure

1990 • 38 citations

Basal Ganglia Dopamine Receptor Autoradiography and Age‐related Movement Disordersa

1988 • 19 citations

Neurotransmitter Theories of Schizophrenia

1978 • 16 citations

Neurotensin-dopamine interactions in the substantia nigra of the rat brain.

1990 • 14 citations

Neurotensin mRNA Expression in Response to Haloperidol Is Decreased in the Dorsolateral Striatum of Aged Ratsa

1992 • 1 citations