Selective disruption of growth hormone transcription machinery by viral infection.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

1990 • 1,211 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally.

1989 • 352 citations

A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells

1987 • 301 citations

Cytoimitiunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system

1986 • 250 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements

1990 • 224 citations

Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation

1991 • 222 citations

Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor.

1987 • 218 citations

Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activity

1990 • 208 citations

Variable Effects of Phosphorylation of Pit-1 Dictated by the DNA Response Elements

1991 • 206 citations

Viral Immunology and Immunopathology

1975 • 202 citations

The Homeodomain Protein, Pit-1/GHF-1, Is Capable of Binding to and Activating Cell-Specific Elements of Both the Growth Hormone and Prolactin Gene Promoters

1990 • 127 citations

Viral perturbation of endocrine function: disordered cell function leads to disturbed homeostasis and disease

1984 • 116 citations

Extinction of growth hormone expression in somatic cell hybrids involves repression of the specific trans-activator GHF-1

1988 • 88 citations

Perturbation of differentiated functions during viral infectionin Vivo I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency

1985 • 63 citations

Induction of Human Growth Hormone Promoter Activity by the Adenosine 3′,5′-Monophosphate Pathway Involves a Novel Responsive Element

1989 • 53 citations

Viral Alteration of Cell Function

1989 • 53 citations

Viral persistence and disease: Cytopathology in the absence of cytolysis

1991 • 40 citations

Lymphocytic choriomeningitis virus selectively alters differentiated but not housekeeping functions: Block in expression of growth hormone gene is at the level of transcriptional initiation

1989 • 31 citations

Perturbation of differentiated functions in Vivo during persistent viral infection III. Decreased growth hormone mRNA

1987 • 29 citations

Growth Hormone Synthesis and Secretion by a Somatomammotroph Cell Line Derived from Normal Adult Pituitary of the Rat*

1988 • 25 citations