Preoperative Serum DNA GSTP1 CpG Island Hypermethylation and the Risk of Early Prostate-Specific Antigen Recurrence Following Radical Prostatectomy

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

Docetaxel plus Prednisone or Mitoxantrone plus Prednisone for Advanced Prostate Cancer

2004 • 5,439 citations

Cancer Statistics, 2004

2004 • 4,026 citations

Docetaxel and Estramustine Compared with Mitoxantrone and Prednisone for Advanced Refractory Prostate Cancer

2004 • 3,606 citations

Gene Silencing in Cancer in Association with Promoter Hypermethylation

2003 • 3,332 citations

Natural History of Progression After PSA Elevation Following Radical Prostatectomy

1999 • 2,993 citations

Molecular regulation of vessel maturation

2003 • 2,446 citations

DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

2001 • 2,050 citations

A gene hypermethylation profile of human cancer.

2001 • 2,043 citations

Free DNA in the serum of cancer patients and the effect of therapy.

1977 • 1,708 citations

Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer. A multi-institutional update

1997 • 1,621 citations

The power and the promise of DNA methylation markers

2003 • 1,544 citations

MethyLight: a high-throughput assay to measure DNA methylation

2000 • 1,382 citations

A Preoperative Nomogram for Disease Recurrence Following Radical Prostatectomy for Prostate Cancer

1998 • 1,249 citations

Immediate Hormonal Therapy Compared with Observation after Radical Prostatectomy and Pelvic Lymphadenectomy in Men with Node-Positive Prostate Cancer

1999 • 1,224 citations

Rapid Clearance of Fetal DNA from Maternal Plasma

1999 • 1,112 citations

Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.

1999 • 920 citations

Prostate Cancer

2003 • 900 citations

Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis.

1994 • 840 citations

Biochemical (Prostate Specific Antigen) Recurrence Probability Following Radical Prostatectomy for Clinically Localized Prostate Cancer

2003 • 663 citations

Microsatellite alterations in plasma DNA of small cell lung cancer patients

1996 • 656 citations

Biochemical (Prostate Specific Antigen) Recurrence Probability Following Radical Prostatectomy for Clinically Localized Prostate Cancer

2003 • 631 citations

Predominant Hematopoietic Origin of Cell-free DNA in Plasma and Serum after Sex-mismatched Bone Marrow Transplantation

2002 • 543 citations

Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate Cancer

2004 • 518 citations

Point mutations of the N‐ras gene in the blood plasma DNA of patients with myelodysplastic syndrome or acute myelogenous leukaemia

1994 • 392 citations

Genetic Analysis of DNA Excreted in Urine: A New Approach for Detecting Specific Genomic DNA Sequences from Cells Dying in an Organism

2000 • 363 citations

Hypermethylation of the Human Glutathione S-Transferase-π Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate

2003 • 298 citations

Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids.

2000 • 275 citations

Presence of tumor DNA in plasma of breast cancer patients: clinicopathological correlations.

1999 • 238 citations

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer

2002 • 203 citations

GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer

2003 • 198 citations

CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: a new prostate cancer biomarker.

1997 • 196 citations

Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients.

2000 • 181 citations

Rapid clearance of plasma Epstein-Barr virus DNA after surgical treatment of nasopharyngeal carcinoma.

2003 • 171 citations

Beyond the genetic lesions: gene inactivation by promoter hypermethylation in human cancer

2000 • 127 citations

Tumor angiogenesis is associated with progression after radical prostatectomy in pT2/pT3 prostate cancer

2000 • 108 citations

p14ARF promoter hypermethylation in plasma DNA as an indicator of disease recurrence in bladder cancer patients.

2002 • 106 citations

Detection of p16 hypermethylation in circulating plasma DNA of non-small cell lung cancer patients

2002 • 102 citations

Methyl-CpG Binding Domain Protein 2 Represses Transcription from Hypermethylated π-Class Glutathione S-Transferase Gene Promoters in Hepatocellular Carcinoma Cells

2002 • 100 citations

Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer

2004 • 96 citations

The molecular and genetic basis of colon cancer

2002 • 75 citations

Expression of p120, Ki‐67 and PCNA as proliferation biomarkers in imprint smears of prostate carcinoma and their prognostic value

2004 • 63 citations

Utilizing Predictions of Early Prostate-Specific Antigen Failure to Optimize Patient Selection for Adjuvant Systemic Therapy Trials

2000 • 48 citations

Prognostic Implication of Microvascular Invasion in Biochemical Failure in Patients Treated with Radical Prostatectomy

2003 • 45 citations

Polyinosinic acid and polycationic liposomes attenuate the hepatic clearance of circulating plasmid DNA.

2001 • 23 citations

Low p27 expression predicts biochemical relapse after radical prostatectomy in patients with clinically localised prostate cancer.

2004 • 13 citations

Adjuvant weekly docetaxel (D) for high-risk prostate cancer patients (pts) after radical prostatectomy (RP): Preliminary data of a multicenter pilot trial

2004 • 9 citations