Back to search

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

Data up to Jan 2025

Published2009
Citations667
References48

Total Citations Per Year

Abstract

References (48)

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

The Immunobiology of Cancer Immunosurveillance and Immunoediting

2004 • 2,788 citations

Regulatory T cells, tumour immunity and immunotherapy

2006 • 2,009 citations

IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors

2004 • 1,635 citations

Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

2002 • 1,454 citations

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

2006 • 1,118 citations

Direct Expansion of Functional CD25+ CD4+ Regulatory T Cells by Antigen-processing Dendritic Cells

2003 • 893 citations

Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

2002 • 785 citations

Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions

2006 • 746 citations

Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells

2004 • 680 citations

Inhibition of the Differentiation of Dendritic Cells From CD34+ Progenitors by Tumor Cells: Role of Interleukin-6 and Macrophage Colony-Stimulating Factor

1998 • 576 citations

Prognostic Value of Tumor-Infiltrating CD4+ T-Cell Subpopulations in Head and Neck Cancers

2006 • 561 citations

In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, Whereas Mature Dendritic Cells Are Located in Peritumoral Areas

1999 • 540 citations

Large-scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells

2004 • 505 citations

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

2008 • 503 citations

High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma

2006 • 491 citations

Human Macrophage–derived Chemokine (MDC), a Novel Chemoattractant for Monocytes, Monocyte-derived Dendritic Cells, and Natural Killer Cells

1997 • 486 citations

CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

2004 • 443 citations

Dendritic Cell Infiltration and Prognosis of Early Stage Breast Cancer

2004 • 437 citations

CD4+CD25high T Cells Are Enriched in the Tumor and Peripheral Blood of Prostate Cancer Patients

2006 • 416 citations

MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells

2006 • 416 citations

Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma

2006 • 412 citations

FOXP3+ Regulatory T Cells Affect the Development and Progression of Hepatocarcinogenesis

2007 • 412 citations

Altering the distribution of Foxp3+ regulatory T cells results in tissue-specific inflammatory disease

2007 • 388 citations

Macrophage-derived Chemokine Is a Functional Ligand for the CC Chemokine Receptor 4

1998 • 376 citations

Specific Recruitment of CC Chemokine Receptor 4–Positive Regulatory T Cells in Hodgkin Lymphoma Fosters Immune Privilege

2006 • 295 citations

Basal-like breast carcinomas: clinical outcome and response to chemotherapy

2006 • 291 citations

Dendritic cells as a major source of macrophage-derived chemokine/CCL22in vitro andin vivo

2001 • 258 citations

The Inducible CXCR3 Ligands Control Plasmacytoid Dendritic Cell Responsiveness to the Constitutive Chemokine Stromal Cell–derived Factor 1 (SDF-1)/CXCL12

2003 • 255 citations

Regulatory T Cell Suppression and Anergy Are Differentially Regulated by Proinflammatory Cytokines Produced by TLR-Activated Dendritic Cells

2004 • 202 citations

Tumor-Infiltrating Foxp3−CD4+CD25+ T Cells Predict Poor Survival in Renal Cell Carcinoma

2007 • 198 citations

Tumor-Infiltrating Cytotoxic T Cells but not Regulatory T Cells Predict Outcome in Anal Squamous Cell Carcinoma

2006 • 134 citations

Immunosuppressive regulatory T cells are associated with aggressive breast cancer phenotypes: a potential therapeutic target

2008 • 132 citations

CCR4-dependent regulatory T cell function in inflammatory bowel disease

2007 • 128 citations

Cell-surface IL-7 receptor expression facilitates the purification of FOXP3+ regulatory T cells

2006 • 127 citations

Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors

2004 • 117 citations

Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors

2004 • 109 citations

Function and recruitment of mucosal regulatory T cells in human chronic Helicobacter pylori infection and gastric adenocarcinoma

2006 • 108 citations

CD4+CD25+ Regulatory T-Cell Frequency in HER-2/neu (HER)-Positive and HER-Negative Advanced-Stage Breast Cancer Patients

2007 • 104 citations

Quantitative and Qualitative Changes in V-J α Rearrangements During Mouse Thymocytes Differentiation

2002 • 97 citations

Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen

2004 • 75 citations

Renal cell carcinoma induces interleukin 10 and prostaglandin E2 production by monocytes

1998 • 60 citations

A Multidisciplinary Approach to the Management of Breast Cancer, Part 1: Prevention and Diagnosis

2007 • 55 citations

Breast carcinoma cells promote the differentiation of CD34+ progenitors towards 2 different subpopulations of dendritic cells with CD1ahighCD86Langerin‐ and CD1a+CD86+Langerin+ phenotypes

2004 • 46 citations

The role of lymphocytes and macrophages in human breast tumorigenesis: an immunohistochemical and morphometric study.

2002 • 41 citations

Telomere length of in vivo expanded CD4+CD25+ regulatory T-cells is preserved in cancer patients

2005 • 35 citations

Human T Cell Activation by Costimulatory Signal-Deficient Allogeneic Cells Induces Inducible Costimulator-Expressing Anergic T Cells with Regulatory Cell Activity

2004 • 34 citations

Cost-effectiveness analysis of strategies for HER2 testing of breast cancer patients in France

2006 • 15 citations

Cited By (0)

Loading...
Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid… (2009) – Cancer Research | Metascience Observatory Explorer