Reduced central leptin sensitivity in rats with diet-induced obesity

Changes in Energy Expenditure Resulting from Altered Body Weight

1995 • 1,926 citations

Identification of targets of leptin action in rat hypothalamus.

1996 • 1,502 citations

Phenotypes of Mouse diabetes and Rat fatty Due to Mutations in the OB (Leptin) Receptor

1996 • 1,074 citations

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1996 • 1,020 citations

Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

1996 • 1,004 citations

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

2000 • 873 citations

Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice

1996 • 873 citations

Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior.

1985 • 731 citations

Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.

1991 • 678 citations

Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats

1997 • 522 citations

Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats

2000 • 501 citations

Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus.

1999 • 347 citations

Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.

1988 • 318 citations

Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism

1994 • 303 citations

Brain glucose sensing and body energy homeostasis: role in obesity and diabetes

1999 • 265 citations

Defense of differfing body weight set points in diet-induced obese and resistant rats

1998 • 252 citations

Intraventricular insulin reduces food intake and body weight of lean but not obese zucker rats

1986 • 230 citations

Leptin Regulation of Agrp and Npy mRNA in the Rat Hypothalamus

2001 • 218 citations

Metabolic differences between obesity-prone and obesity-resistant rats

1990 • 185 citations

Defense of body weight against chronic caloric restriction in obesity-prone and -resistant rats

2000 • 152 citations

Initiation and perpetuation of obesity and obesity resistance in rats

1989 • 148 citations

Dysregulation of arcuate nucleus preproneuropeptide Y mRNA in diet-induced obese rats

1997 • 133 citations

Arcuate NPY neurons and energy homeostasis in diet-induced obese and resistant rats

1999 • 132 citations

Low Plasma Leptin in Response to Dietary Fat in Diabetes- and Obesity-Prone Mice

1997 • 125 citations

Metabolic effects of neuropeptide Y injections into the paraventricular nucleus of the hypothalamus

1990 • 94 citations

Adjustments in daily energy expenditure to caloric restriction and weight loss by adult obese and lean Zucker rats.

1990 • 38 citations

Ontogeny of neuropeptide Y expression in response to deprivation in lean Zucker rat pups

1998 • 34 citations

Similar effects of NPY on energy metabolism and on plasma insulin in adrenalectomized ob/ob and lean mice

1993 • 34 citations

Insulin binding in the hypothalamus of lean and genetically obese Zucker rats

1989 • 32 citations

Feeding responses of Zucker fatty rat to 2-deoxy-D-glucose, norepinephrine, and insulin

1980 • 31 citations

Effects of Intracerebroventricular Infusion of Leptin in Obese Zucker Rats

1997 • 28 citations

Diet cycling and age alter weight gain and insulin levels in rats

1994 • 27 citations

Naloxone-induced anorexia increases neuropeptide Y concentrations in the dorsomedial hypothalamus: Evidence for neuropeptide Y-opioid interactions in the control of food intake

1994 • 18 citations