Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Development of the Drosophila retina, a neurocrystalline lattice

1976 • 1,028 citations

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185

1986 • 1,020 citations

erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

1987 • 1,015 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

Neuronal differentiation in the Drosophila ommatidium

1987 • 532 citations

Notch is required for successive cell decisions in the developing Drosophila retina.

1989 • 473 citations

The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates

1990 • 430 citations

Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain

1987 • 421 citations

Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster

1976 • 395 citations

Cell fate in the Drosophila ommatidium

1987 • 363 citations

The white gene as a marker in a new P-element vector for gene transfer inDrosophila

1987 • 355 citations

The Drosophila gene torso encodes a putative receptor tyrosine kinase

1989 • 327 citations

Determinants of heat shock-induced chromosome puffing

1985 • 281 citations

Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila

1987 • 279 citations

The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.

1990 • 267 citations

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

1988 • 242 citations

Analysis of the Promoter of the ninaE Opsin Gene in Drosophila melanogaster

1987 • 230 citations

Function of torso in determining the terminal anlagen of the Drosophila embryo

1988 • 228 citations

Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster.

1990 • 227 citations

Cuticle protein genes of Drosophila: Structure, organization and evolution of four clustered genes

1982 • 226 citations

A second opsin gene expressed in the ultraviolet-sensitive R7 photoreceptor cells of Drosophila melanogaster

1987 • 215 citations

Localized surface activity of torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila.

1989 • 213 citations

Upstream elements necessary for optimal function of the hsp 70 promoter in transformed flies

1984 • 213 citations

Cell-cell interaction in the drosophila retina: The bride of sevenless gene is required in photoreceptor cell R8 for R7 cell development

1988 • 209 citations

A multifaceted approach to neural development

1989 • 194 citations

A rhodopsin gene expressed in photoreceptor cell R7 of the Drosophila eye: homologies with other signal-transducing molecules

1987 • 193 citations

rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye

1988 • 189 citations

Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain

1988 • 177 citations

Cell lineage in the developing retina of Drosophila

1979 • 169 citations

Differential splicing generates a nervous system—Specific form of drosophila neuroglian

1990 • 165 citations

Activation of the feline c-fms proto-oncogene: Multiple alterations are required to generate a fully transformed phenotype

1988 • 164 citations

Induction of cell fate in the Drosophila retina: the bride of sevenless protein is predicted to contain a large extracellular domain and seven transmembrane segments.

1990 • 164 citations

The role of cell-cell interaction in the development of the drosophila visual system

1990 • 163 citations

The sevenless+ protein is expressed apically in cell membranes of developing Drosophila retina; it is not restricted to cell R7

1987 • 124 citations

The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements.

1989 • 99 citations

Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster.

1988 • 93 citations

Ubiquitous Expression of sevenless : Position-Dependent Specification of Cell Fate

1989 • 79 citations

Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough.

1990 • 78 citations

cell clones and pattern formation: Studies onsevenless, a mutant ofDrosophila melanogaster

1979 • 77 citations

Development of the Drosophila retina: Inductive events studied at single cell resolution

1989 • 71 citations

Ommatidia in the developing Drosophila eye require and can respond to sevenless for only a restricted period

1989 • 69 citations

The fine structure of the eye imaginal disks in muscoid flies

1975 • 59 citations

Ultrastructure of the retina ofDrosophila melanogaster: The mutantora(outer rhabdomeres absent) and its inhibition of degeneration inrdgB(retinal degeneration-B)

1987 • 55 citations

Dynamics of Drosophila eye development and temporal requirements of sevenless expression

1989 • 54 citations

Regulation of the complex pattern of sevenless expression in the developing Drosophila eye.

1989 • 51 citations

Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate

1988 • 39 citations

Photophobe (Ppb), a Drosophila mutant with a reversed sign of phototaxis; the mutation shows an allele-specific interaction with sevenless.

1988 • 26 citations

Ultrastructure of the retina of Drosophila melanogaster. the mutant ora (outer rhabdomeres absent) and its inhibition of degeneration in rdgB (retinal degeneration-B)

1987 • 22 citations

Cellular Communication in the Developing Drosophila Eye

2007 • 1 citations