Topography of Alzheimer’s Disease: Involvement of Association Neocortices and Connected Regions; Pathological, Metabolic and Cognitive Correlations; Relation to Evolution

“Mini-mental state”

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Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

1986 • 3,430 citations

Evolution at Two Levels in Humans and Chimpanzees

1975 • 2,796 citations

Neural Darwinism: The Theory Of Neuronal Group Selection

1987 • 2,523 citations

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

1984 • 2,199 citations

Cholinergic innervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (Substantia innominata), and hypothalamus in the rhesus monkey

1983 • 1,898 citations

The Working Brain

1973 • 1,892 citations

The working brain : an introduction to neuropsychology

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Selected Writings of John Hughlings Jackson

1959 • 1,229 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Wechsler Adult Intelligence Scale

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Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1985 • 1,125 citations

Great Books of the Western World

1952 • 1,071 citations

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

1985 • 979 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Noninvasive determination of local cerebral metabolic rate of glucose in man

1980 • 928 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder

1987 • 855 citations

Obsessive-Compulsive Disorder in Children and Adolescents

1989 • 820 citations

共やくエクイン・エストロゲン(Premarin)服用閉経婦人の血清エクイリン,エストロン,エストラジオール値

1980 • 725 citations

Cerebral Glucose Metabolism in Childhood-Onset Obsessive-Compulsive Disorder

1989 • 676 citations

Perforant pathway changes and the memory impairment of Alzheimer's disease

1986 • 665 citations

Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients

1989 • 596 citations

Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices

1987 • 569 citations

Positron emission tomography in Alzheimer's disease

1986 • 563 citations

Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder

1990 • 546 citations

Cells of origin and terminal distribution of descending projections of the rat somatic sensory cortex

1977 • 520 citations

Dementia of the Alzheimer Type

1980 • 518 citations

Conservation of Brain Amyloid Proteins in Aged Mammals and Humans with Alzheimer's Disease

1987 • 472 citations

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1989 • 463 citations

Dementia of the Alzheimer Type

1981 • 451 citations

Nerve Growth Factor Gene Expression in the Developing Rat Brain

1986 • 436 citations

A NEW DEFINITION OF ALZHEIMER'S DISEASE: A HIPPOCAMPAL DEMENTIA

1985 • 422 citations

Obsessive-compulsive disorder in children and adolescents

1989 • 421 citations

The neuropathology of aminergic nuclei in Alzheimer's disease

1988 • 419 citations

Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease

1985 • 414 citations

Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in alzheimer's disease

1985 • 407 citations

PATHOLOGY OF THE NERVOUS SYSTEM

1949 • 394 citations

Abnormal phosphorylation of the microtubule-associated protein? (tau) in Alzheimer cytoskeletal pathology

1987 • 393 citations

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain

1988 • 386 citations

Distribution of cerebral degeneration in Alzheimer's disease

1976 • 381 citations

Clinical Neurology of Aging

2010 • 361 citations

Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type

1988 • 352 citations

Relations between Neuropsychological and Cerebral Metabolic Asymmetries in Early Alzheimer's Disease

1985 • 345 citations

ALZHEIMER'S PRESENILE DEMENTIA, SENILE DEMENTIA OF ALZHEIMER TYPE AND DOWN'S SYNDROME IN MIDDLE AGE FORM AN AGE RELATED CONTINUUM OF PATHOLOGICAL CHANGES

1984 • 344 citations

The development of the pathologic changes of Alzheimer's disease and senile dementia in patients with Down's syndrome.

1973 • 340 citations

Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography

1988 • 289 citations

Evolution of the nervous system

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Pathology of the Nervous System

1969 • 284 citations

Neocortical Metabolic Abnormalities Precede Nonmemory Cognitive Defects in Early Alzheimer's-Type Dementia

1986 • 274 citations

Amyloid Protein Precursor Messenger RNAs: Differential Expression in Alzheimer's Disease

1988 • 254 citations

Absence of Linkage of Chromosome 21q21 Markers to Familial Alzheimer's Disease

1988 • 245 citations

Gene Encoding the β Subunit of S100 Protein Is on Chromosome 21: Implications for Down Syndrome

1988 • 222 citations

Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brain.

1988 • 212 citations

The Molecular Basis of Evolution

1961 • 205 citations

Abnormalities of the nucleus basalis in Down's syndrome

1985 • 199 citations

Interactions between the microtubule-associated tau proteins and S100b regulate tau phosphorylation by the Ca2+/calmodulin-dependent protein kinase II.

1988 • 189 citations

Intercorrelations of regional cerebral glucose metabolic rates in Alzheimer's disease

1987 • 183 citations

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.

1988 • 181 citations

STUDIES ON THE COMPARATIVE ANATOMY OF THE GANGLION BASALE OF MEYNERT

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Evolution of the Nervous System

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A monoclonal antibody to non-phosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease

1987 • 161 citations

Familial alzheimer's disease in american descendants of the volga germans: Probable genetic founder effect

1988 • 145 citations

Dementia of the Alzheimer type

1987 • 143 citations

Clinical Neuropsychology

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Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged

1986 • 129 citations

Correlation between senile plaque and neurofibrillary tangle counts in cerebral cortex and neuronal counts in cortex and subcortical structures in Alzheimer's disease

1985 • 127 citations

The primate brain

1970 • 126 citations

Rate of ventricular enlargement in dementia of the Alzheimer type correlates with rate of neuropsychological deterioration

1987 • 120 citations

Stability of metabolic and neuropsychological asymmetries in dementia of the Alzheimer type

1986 • 109 citations

Dopaminergic neurotransmitter systems in Alzheimer's disease and in Down's syndrome at middle age.

1987 • 92 citations

Quantitative comparison of the amygdala in insectivores and primates

1977 • 91 citations

Verteilungsmuster der senilen Ver�nderungen im Gehirn

1968 • 89 citations

Cortical atrophy in senile dementia of the Alzheimer type is mainly due to a decrease in cortical length

1985 • 88 citations

Quantitative computed tomography in dementia of the Alzheimer type

1986 • 87 citations

Clinical Neurology of Aging

1985 • 72 citations

Alzheimer's disease: An olfactory connection?

1988 • 70 citations

Verteilungsmuster der senilen Vernderungen im Gehirn: Die Beteiligung des limbischen Systems bei hirnatrophischen Prozessen des Seniums und bei Morbus Alzheimer

1968 • 70 citations

The Neurobiology of Down syndrome

1986 • 68 citations

Evolution of the Nervous System, 2nd Edn

1983 • 63 citations

TOPOGRAPHY OF NEUROFIBRILLARY TANGLES AND GRANULOVACUOLES IN HIPPOCAMPI OF PATIENTS WITH DOWN'S SYNDROME: QUANTITATIVE COMPARISON WITH NORMAL AGEING AND ALZHEIMER'S DISEASE

1981 • 62 citations

Ultrastructure of Senile Dementia and of Experimental Analogs

1972 • 61 citations

CHROMOSOMAL PHYLOGENY OF THE PRIMATES

1978 • 61 citations

Hypothesis: Alzheimer's disease is a phylogenetic disease

1989 • 60 citations

Brain evolution and Alzheimer's disease.

1988 • 59 citations

Regional weight loss of the cerebral cortex and some subcortical nuclei in senile dementia of the Alzheimer type

1988 • 52 citations

Alzheimer's Disease: Metabolic Uncoupling of Associative Brain Regions

1986 • 39 citations

The Neurobiology of Down syndrome

1987 • 37 citations

Topography of nerve cell loss from the locus caeruleus in middle aged persons with Down's syndrome

1988 • 28 citations

Septal nuclei in primate phylogeny. A quantitative investigation

1966 • 28 citations

Genetic linkage studies in Alzheimer's disease

1986 • 24 citations

Quantitative comparison of cerebral glucose metabolic rates from two positron emission tomographs.

1989 • 21 citations

A Phylogenetic Hypothesis for Alzheimer’s Disease

1988 • 6 citations

Epilepsy in Young People (Portsmouth Symposium, June, 1986)

1988 • 5 citations