Expression of the Alzheimer amyloid precursor gene transcripts in the human brain

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1984 • 1,633 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

1985 • 979 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides.

1987 • 589 citations

Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices

1987 • 569 citations

Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2

1986 • 535 citations

Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes.

1983 • 478 citations

Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.

1988 • 444 citations

Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease.

1988 • 392 citations

Localization of Amyloid β Protein Messenger RNA in Brains from Patients with Alzheimer's Disease

1987 • 297 citations

Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects

1966 • 293 citations

The incidence of cerebral amyloid angiopathy in Alzheimer's disease

1975 • 276 citations

Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families

1987 • 275 citations

The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid β-protein gene

1987 • 271 citations

Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease.

1987 • 222 citations

Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brain.

1988 • 212 citations

Neuropathology of Organic Brain Syndromes Associated with Aging

1972 • 182 citations

Gene Dosage of the Amyloid β Precursor Protein in Alzheimer's Disease

1987 • 173 citations

Laminar distribution of neocortical senile plaques in senile dementia of the alzheimer type

1986 • 154 citations

Absence of Duplication of Chromosome 21 Genes in Familial and Sporadic Alzheimer's Disease

1987 • 142 citations

The Amyloid β Protein Gene Is Not Duplicated in Brains from Patients with Alzheimer's Disease

1987 • 139 citations

A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors

1988 • 119 citations

Senile Degenerative Brain Lesions and Dementia

1975 • 92 citations

Alzheimer's disease. The commonest form of amyloidosis.

1983 • 76 citations