Identification and Initial Characterization of Four Novel Members of the Interleukin-1 Family

How to measure and predict the molar absorption coefficient of a protein

1995 • 3,771 citations

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

1992 • 2,495 citations

A family of human receptors structurally related to Drosophila Toll

1998 • 1,735 citations

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

1997 • 1,137 citations

Molecular Cloning of the Interleukin-1β Converting Enzyme

1992 • 1,115 citations

The interleukin‐1 family: 10 years of discovery ¹

1994 • 784 citations

Interleukin-18 Binding Protein

1999 • 759 citations

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

1991 • 677 citations

Structural Basis for FGF Receptor Dimerization and Activation

1999 • 597 citations

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

1998 • 573 citations

Purification and Characterization of the Human Interleukin-18 Receptor

1997 • 471 citations

An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin.

1993 • 427 citations

Three-Dimensional Structures of Acidic and Basic Fibroblast Growth Factors

1991 • 386 citations

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

1986 • 384 citations

A putative protein of a growth specific cDNA from BALB/C‐3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor

1989 • 374 citations

Overview of interleukin-18: more than an interferon-γ inducing factor

1998 • 371 citations

Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice

1995 • 365 citations

Acute and Recurrent Infection with Herpes Simplex Virus in the Mouse: a Model for Studying Latency and Recurrent Disease

1975 • 337 citations

cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.

1991 • 326 citations

Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling

1998 • 326 citations

Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β

1997 • 258 citations

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

1996 • 241 citations

A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

1997 • 235 citations

Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain

1999 • 226 citations

Human keratinocytes produce but do not process pro-interleukin-1 (IL-1) beta. Different strategies of IL-1 production and processing in monocytes and keratinocytes.

1991 • 209 citations

The Interleukin 1 Receptor: Ligand Interactions and Signal Transduction

1998 • 178 citations

Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen.

1989 • 167 citations

Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.

1989 • 166 citations

Fibroblast growth factor receptors (FGFRs) and their roles in limb development

1999 • 160 citations

Structure and Expression of the mRNA Encoding a Novel Fibroblast Growth Factor, FGF-18

1998 • 150 citations

Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2

1987 • 145 citations

Expression of ST2, an Interleukin-1 Receptor Homologue, Is Induced by Proinflammatory Stimuli

1997 • 125 citations

In Vivo Production of Cytokines and (C-C) Chemokines in Human Recurrent Herpes Simplex Lesions--Do Herpes Simplex Virus-Infected Keratinocytes Contribute to Their Production?

1998 • 98 citations

IL1HY1: A Novel Interleukin-1 Receptor Antagonist Gene

1999 • 98 citations

Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation

1997 • 96 citations

Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL1R-rp2)

1996 • 79 citations

ST2/T1 Protein Functionally Binds to Two Secreted Proteins from Balb/c 3T3 and Human Umbilical Vein Endothelial Cells but Does Not Bind Interleukin 1

1995 • 74 citations

Purification and characterization of human recombinant interleukin-1 beta.

1987 • 72 citations

Intralesional Cytokines in Chronic Oxazolone-Induced Contact Sensitivity Suggest Roles for Tumor Necrosis Factor α and Interleukin-4

1998 • 63 citations

Purification and Characterization of Human Recombinant Precursor Interleukin 1 β

1989 • 57 citations

Formation of an active dimer during storage of interleukin-1 receptor antagonist in aqueous solution

1996 • 50 citations

Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family

1999 • 49 citations

Activation of the IL-1 Gene in UV-Irradiated Mouse Skin: Association with Inflammatory Sequelae and Pharmacologic Intervention

1991 • 32 citations