Overexpression of platelet-derived growth factor receptor α in breast cancer is associated with tumour progression

PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors

2003 • 2,224 citations

The discovery of receptor tyrosine kinases: targets for cancer therapy

2004 • 1,186 citations

Regulation of PDGF and its receptors in fibrotic diseases

2004 • 697 citations

Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

2003 • 665 citations

PDGF and cardiovascular disease

2004 • 463 citations

PDGF signaling in cells and mice

2004 • 377 citations

Developmental roles of platelet‐derived growth factors

2001 • 365 citations

PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

2004 • 320 citations

Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines.

1987 • 266 citations

KIT and Platelet-Derived Growth Factor Receptor Alpha Tyrosine Kinase Gene Mutations and KIT Amplifications in Human Solid Tumors

2004 • 201 citations

Switching on kinases: oncogenic activation of BRAF and the PDGFR family

2004 • 180 citations

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

1998 • 175 citations

Targeting Bcl-2 and Bcl-X with nonpeptidic small-molecule antagonists

2003 • 174 citations

Modern Surgical Pathology

2009 • 149 citations

Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors

2002 • 130 citations

Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma.

1995 • 125 citations

Dysregulation of cellular signaling by HER2 in breast cancer

2003 • 123 citations

Degenerate Oligonucleotide Primed-Polymerase Chain Reaction-Based Array Comparative Genomic Hybridization for Extensive Amplicon Profiling of Breast Cancers

2001 • 100 citations

Expression of Platelet-Derived Growth Factor-aa Receptor Is Associated With Tumor Progression in Clear Cell Renal Cell Carcinoma

2003 • 80 citations

Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma

2004 • 72 citations

Modern Surgical Pathology

2003 • 66 citations

Inhibition of apoptosis in human breast cancer cells: Role in tumor progression to the metastatic state

2002 • 64 citations

Expression of Platelet-Derived Growth Factor-α Receptor Is Associated With Tumor Progression in Clear Cell Renal Cell Carcinoma

2003 • 63 citations

The Association of HER-2/neu Amplification With Breast Cancer Recurrence

2000 • 58 citations

Detection of amplified oncogenes by genome DNA microarrays in human primary esophageal squamous cell carcinoma: comparison with conventional comparative genomic hybridization analysis

2003 • 56 citations

Structure, Organization, and Transcription Units of the Human α-Platelet-Derived Growth Factor Receptor Gene, PDGFRA

1995 • 53 citations

c-KIT and PDGFRA in breast phyllodes tumours: overexpression without mutations?

2004 • 46 citations

Bcl-2 with loss of apoptosis allows accumulation of genetic alterations: A pathway to metastatic progression in human breast cancer

2000 • 40 citations

Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review)

2003 • 33 citations

The malignant clone in Waldenstrom's macroglobulinemia

2003 • 24 citations