T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

2006 • 6,720 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

Identification and Functional Characterization of Human Cd4+Cd25+ T Cells with Regulatory Properties Isolated from Peripheral Blood

2001 • 1,293 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Epigenetic Control of the foxp3 Locus in Regulatory T Cells

2007 • 1,181 citations

Transient expression of FOXP3 in human activated nonregulatory CD4⁺ T cells

2006 • 973 citations

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

2005 • 957 citations

Development of allergen-specific T-cell memory in atopic and normal children

1999 • 925 citations

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

2007 • 836 citations

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 • 773 citations

DNA methylation controls Foxp3 gene expression

2008 • 729 citations

Regulatory T cells in cancer

2006 • 717 citations

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17–producing cells

2008 • 715 citations

Foxp3 in control of the regulatory T cell lineage

2007 • 690 citations

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3⁺ conventional T cells

2007 • 658 citations

Th2 and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis

2007 • 634 citations

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

2008 • 474 citations

Isolation and functional characterization of regulatory CD25^brightCD4⁺ T cells from the target organ of patients with rheumatoid arthritis

2003 • 452 citations

Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells

2009 • 418 citations

Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma

2007 • 405 citations

Human CD4+CD25+ regulatory T cells

2004 • 389 citations

Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

2009 • 307 citations

Inhibition of Human CD4+CD25+high Regulatory T Cell Function

2002 • 266 citations

The regulation of allergy and asthma

2006 • 263 citations

FOXP3: Not just for regulatory T cells anymore

2006 • 165 citations

The IL-4 Receptor α-Chain-Binding Cytokines, IL-4 and IL-13, Induce Forkhead Box P3-Expressing CD25+CD4+ Regulatory T Cells from CD25−CD4+ Precursors

2005 • 158 citations

Children with egg allergy have evidence of reduced neonatal CD4+CD25+CD127lo/− regulatory T cell function

2008 • 153 citations

CD49d provides access to “untouched” human Foxp3+ Treg free of contaminating effector cells

2008 • 144 citations

Impairment of T-regulatory cells in cord blood of atopic mothers

2008 • 143 citations

Early markers of allergic disease in a primary prevention study using probiotics: 2.5‐year follow‐up phase

2008 • 93 citations

Impairment of T helper and T regulatory cell responses at birth

2008 • 89 citations

DNA Methylation Analysis as a Tool for Cell Typing

2006 • 68 citations

Cutting Edge: IL-4-Induced Protection of CD4+CD25− Th Cells from CD4+CD25+ Regulatory T Cell-Mediated Suppression

2006 • 60 citations

Association between CD4+CD25high T cells and atopy in children

2007 • 32 citations