Back to search

[3H]‐MK 912 binding delineates two α2‐adrenoceptor subtypes in rat CNS one of which is identical with the cloned pA2d α2‐adrenoceptor

Data up to Jan 2025

Published1992
Citations89
References38

Total Citations Per Year

Abstract

References (38)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

A functional basis for classification of α-adrenergic receptors

1977 • 802 citations

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor

1987 • 792 citations

Differentiation of receptors responsive to isoproterenol

1967 • 484 citations

Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.

1988 • 440 citations

Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype.

1988 • 307 citations

Heterogeneity of alpha-2 adrenergic receptors

1985 • 297 citations

Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2.

1990 • 287 citations

An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.

1990 • 266 citations

Isolation of rat genomic clones encoding subtypes of the alpha 2-adrenergic receptor. Identification of a unique receptor subtype

1991 • 220 citations

Pharmacological classification of adrenergic α receptors in the guinea pig

1978 • 164 citations

Molecular characterization of a rat alpha 2B-adrenergic receptor.

1990 • 163 citations

Molecular characterization of α1- and α2-adrenoceptors

1991 • 153 citations

Delineation of rat kidney α2A- and α2B-adrenoeeptors with [3H]RX821002 radiollgand binding: computer modelling reveals that guanfacine is an α2A-selective compound

1991 • 137 citations

Expression of three alpha 2-adrenergic receptor subtypes in rat tissues: implications for alpha 2 receptor classification.

1990 • 131 citations

Agonist versus antagonist binding to alpha-adrenergic receptors.

1980 • 118 citations

Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line.

1991 • 116 citations

Characterization of alpha-2 adrenergic receptors in the OK cell, an opossum kidney cell line.

1988 • 112 citations

Pharmacological characterization of rat alpha 2-adrenergic receptors.

1991 • 110 citations

Distribution of α2-adrenergic receptor mRNAs in the rat CNS

1991 • 109 citations

Novel α2-adrenoceptor antagonists show selectivity for α2A- and α2B-adrenoceptor subtypes

1989 • 109 citations

Further Characterization of the Guinea Pig Cerebral Cortex Idazoxan Receptor: Solubilization, Distinction from the Imidazole Site, and Demonstration of Cirazoline as an Idazoxan Receptor‐Selective Drug

1990 • 103 citations

Interactions of Agonists with Platelet α2-Adrenergic Receptors

1982 • 102 citations

Rat Spinal Cord α2‐Adrenoceptors are of the α2A‐Subtype: Comparison with α2A‐ and α2B‐Adrenoceptors in Rat Spleen, Cerebral Cortex and Kidney Using 3H‐RX821002 Ligand Binding

1991 • 79 citations

Molecular cloning, sequencing and expression of an ?2-adrenergic receptor complementary DNA from rat brain

1990 • 68 citations

Delineation of three pharmacological subtypes of α2‐adrenoceptor in the rat kidney

1991 • 60 citations

α2-Adrenoceptors in rat hypothalamus and cerebral cortex: functional evidence for pharmacologically distinct subpopulations

1985 • 58 citations

The rat α2‐C4 adrenergic receptor gene encodes a novel pharmacological subtype

1991 • 51 citations

Heterogeneos 3H-rauwolscine binding sites in rat cortex: Two alpha2-adrenoceptor subtypes or an additional non-adrenergic interaction?

1988 • 42 citations

Adrenoceptors: Structure, Mechanisms, Function

1991 • 39 citations

Heterogeneity of α2‐adrenoceptors in rat cortex but not human platelets can be defined by 8‐OH‐DPAT, RU 24969 and methysergide

1990 • 33 citations

[3H]L-657, 743 (MK-912): A new, high affinity, selective radioligand for brain α2-adrenoceptors

1989 • 29 citations

Agonist binding at alpha2-adrenoceptors of human platelets using 3H-UK-14,304: regulation by Gpp(NH)p and cations

1987 • 26 citations

Antinociceptive Actions of α2‐Adrenoceptor Agonists in the Rat Spinal Cord: Evidence for Antinociceptive α2Adrenoceptor Subtypes and Dissociation of Antinociceptive α2‐Adrenoceptors from Cyclic AMP

1990 • 23 citations

Differential blockade by (?)mianserin of the alpha2-adrenoceptors mediating inhibition of noradrenaline and serotonin release from rat brain synaptosomes

1983 • 19 citations

Pharmacological evidence for alpha 2c and alpha 2d adrenergic receptor subtypes

1991 • 12 citations

Structural and Pharmacological Differences between Codfish and Rat Brain α1‐Adrenergic Receptors Revealed by Photoaffinity Labeling with 125I‐APDQ

1986 • 9 citations

Cited By (0)

Loading...
[3H]‐MK 912 binding delineates two α2‐adrenoceptor subtypes in rat CNS one of which is… (1992) – British Journal of Pharmacology | Metascience Observatory Explorer