Heterogeneity of alpha-2 adrenergic receptors

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

On some physiological actions of ergot

1906 • 980 citations

A functional basis for classification of α-adrenergic receptors

1977 • 802 citations

α-Adrenoceptor subclassification

1981 • 492 citations

Differentiation of receptors responsive to isoproterenol

1967 • 484 citations

Alpha-adrenoceptor subclassification.

1981 • 426 citations

Radioligand Binding Studies of Adrenergic Receptors: New Insights into Molecular and Physiological Regulation

1980 • 313 citations

Role of phosphatidylinositol turnover in alpha1 and of adenylate cyclase inhibition in alpha2 effects of catecholamines

1980 • 298 citations

.alpha.2 Adrenoceptors: classification, localization, mechanisms and targets for drugs

1982 • 290 citations

beta-Adrenergic Receptor Subtypes: Properties, Distribution, and Regulation

1981 • 277 citations

Comparison of beta adrenergic receptor subtypes in mammalian tissues.

1979 • 245 citations

Characterization of α1-and α2-Adrenergic Receptors

1983 • 230 citations

[3H]rauwolscine (α-yohimbine): A specific antagonist radioligand for brain α2-adrenergic receptors

1981 • 186 citations

[3H]rauwolscine and [3H]yohimbine binding to rat cerebral and human platelet membranes: Possible heterogeneity of α2-adrenoceptors

1982 • 184 citations

Characterization of α2-adrenergic receptors on human platelets using [3H]yohimbine

1980 • 166 citations

Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: an electrophysiological study.

1982 • 155 citations

On the Physiology of the Salivary Secretion

1878 • 145 citations

The pharmacological classification of adrenergic alpha 1 and alpha 2 receptors and their mechanisms of action.

1979 • 143 citations

Human platelet α2-adrenergic receptors: Labeling with 3H-yohimbine, a selective antagonist ligand

1981 • 142 citations

Functional evidence for two stereochemically different alpha-2 adrenoceptors regulating central norepinephrine and serotonin release.

1983 • 123 citations

Pharmacological Characterizations of Adrenergic Receptors in Human Adipocytes

1981 • 103 citations

Interactions of Agonists with Platelet α₂-Adrenergic Receptors

1982 • 102 citations

Characterization of alpha-adrenergic receptor subtypes in the rat renal cortex. Differential regulation of alpha 1- and alpha 2-adrenergic receptors by guanyl nucleotides and Na.

1982 • 102 citations

Role of alpha1 adrenoceptors in the turnover of phosphatidylinositol and of alpha2 adrenoceptors in the regulation of cyclic AMP accumulation in hamster adipocytes

1980 • 90 citations

Agonistic and antagonistic effects of various ?-adrenergic agonists in human platelets

1979 • 78 citations

Regulation of autonomic receptors in rat submandibular gland.

1982 • 69 citations

Alpha 2-adrenergic receptors in neuroblastoma x glioma hybrid cells. Characterization with agonist and antagonist radioligands and relationship to adenylate cyclase.

1982 • 69 citations

On the Physiology of the Salivary Secretion

1888 • 66 citations

The characteristics of adrenoceptors in homogenates of human cerebral cortex labelled by (3H)-rauwolscine

1983 • 65 citations

Characterization of alpha-adrenergic receptors in human platelets using [3H]clonidine.

1981 • 64 citations

Characteristics of the [3H]-yohimbine binding on rat brain ?2

1982 • 63 citations

Alterations in central and peripheral adrenergic receptors in deoxycorticosterone/salt hypertensive rats

1980 • 56 citations

Characterization of [3H]yohimbine binding to putative alpha-2 adrenergic receptors in neonatal rat lung.

1982 • 56 citations

α2-Adrenergic receptors appear in rat salivary glands after reserpine treatment

1980 • 53 citations

THE CHARACTERISTICS OF [³H]‐CLONIDINE BINDING TO ANα‐ADRENOCEPTOR IN MEMBRANES FROM GUINEA‐PIG KIDNEY

1979 • 51 citations

ChemInform Abstract: α2 ADRENOCEPTORS: CLASSIFICATION, LOCALIZATION, MECHANISMS AND TARGETS FOR DRUGS

1983 • 48 citations

Identification of alpha adrenoceptor subtypes in dog arteries by (3H) yohimbine and (3H) prazosin

1982 • 47 citations

[3H]Prazosin and [3H]clonidine binding to α-adrenoceptors in membranes prepared from regions of rat kidney

1981 • 44 citations

The selectivity of some ergot derivatives for α1 and α2-adrenoceptors of rat cerebral cortex

1983 • 43 citations

α-Adrenergic Receptors in Human Adipocyte Membranes: Direct Determination by [³H]Yohimbine Binding

1981 • 41 citations

Alpha 2-adrenergic receptor in intestinal epithelial cells. Identification by [3H]yohimbine and failure to inhibit cyclic AMP accumulation.

1983 • 41 citations

Dissociation of presynaptic α2-adrenoceptors following prazosin administration: Presynaptic effect of prazosin

1983 • 40 citations

Comparison of alpha-2 adrenergic receptors and their regulation in rodent and porcine species.

1984 • 35 citations

Solubilization and characterization of putative alpha-2 adrenergic isoceptors from the human platelet and the rat cerebral cortex.

1985 • 33 citations

Postsynaptic localization of alpha 2-adrenergic receptors in rat submandibular gland

1981 • 32 citations

Postsynaptic alpha 2-adrenoceptors predominate over alpha 1-adrenoceptors in canine tracheal smooth muscle and mediate neuronal and hormonal alpha-adrenergic contraction.

1983 • 32 citations

Identification of α2-adrenergic receptors in human fat cell membranes by [3H]chlonidine binding

1980 • 32 citations

Alpha-1 adrenoceptors mediate secretory responses to norepinephrine in innervated and denervated rat submaxillary glands.

1984 • 30 citations

Characterization of adenylate cyclase-coupled alpha 2-adrenergic receptors in rat renal cortex using [3H]yohimbine.

1982 • 25 citations

Characterization of autonomic receptors in the rat sublingual gland by biochemical and radioligand assays

1982 • 20 citations

Neurochemical effects of long-term ingestion of ethanol by Sinclair (S-1) swine

1983 • 20 citations

Alpha-2 adrenergic regulation of norepinephrine release in the rat submandibular gland as measured by HPLC-EC

1984 • 19 citations

Differential blockade by (?)mianserin of the alpha2-adrenoceptors mediating inhibition of noradrenaline and serotonin release from rat brain synaptosomes

1983 • 19 citations

Characterization of alpha-adrenoceptors in rat and guinea pig tissues using radiolabeled agonists and antagonists.

1980 • 14 citations

3H-yohimbine binding to guinea-pig kidney and calf cerebral cortex membranes: comparison with human platelets.

1983 • 11 citations