Ectopic Expression of Cyclin D1 but Not Cyclin E Induces Anchorage-Independent Cell Cycle Progression

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Principles of CDK regulation

1995 • 3,267 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

Role of cell shape in growth control

1978 • 2,434 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

1994 • 2,122 citations

Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

1993 • 1,605 citations

Agar suspension culture for the selective assay of cells transformed by polyoma virus

1964 • 1,265 citations

Human Cyclin E, a Nuclear Protein Essential for the G₁-to-S Phase Transition

1995 • 1,132 citations

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

1993 • 1,057 citations

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1992 • 1,031 citations

Acceleration of the G₁/S Phase Transition by Expression of Cyclins Dl and E with an Inducible System

1994 • 986 citations

D-type cyclins

1995 • 978 citations

Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle

1995 • 918 citations

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53

1990 • 801 citations

Cyclin-Dependent Regulation of G ₁ in Mammalian Fibroblasts

1993 • 767 citations

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

1975 • 747 citations

Cyclins and cancer

1991 • 701 citations

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

1994 • 659 citations

Anchorage and growth regulation in normal and virus‐transformed cells

1968 • 547 citations

Different Roles for Cyclins D1 and E in Regulation of the G₁-to-S Transition

1995 • 469 citations

Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein.

1996 • 453 citations

A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression

1993 • 399 citations

Dependence of Cyclin E-CDK2 Kinase Activity on Cell Anchorage

1996 • 371 citations

Cyclin D1 Is Dispensable for G₁ Control in Retinoblastoma Gene-Deficient Cells Independently of cdk4 Activity

1995 • 370 citations

Cyclin dependent kinase regulation

1995 • 286 citations

Structure and cell cycle-regulated transcription of the human cyclin A gene.

1994 • 272 citations

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

1995 • 254 citations

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein.

1994 • 253 citations

Cyclin A-Associated Kinase Activity Is Rate Limiting for Entrance into S Phase and Is Negatively Regulated in G₁ by p27^Kip1

1995 • 252 citations

Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1.

1996 • 227 citations

Mammalian G1 cyclins

1994 • 219 citations

Common Principles in Cell Adhesion

1996 • 199 citations

Multiple members of the E2F transcription factor family are the products of oncogenes.

1995 • 197 citations

Integrating with integrins.

1994 • 189 citations

Cyclins, CDKs and cancer

1995 • 176 citations

DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control

1994 • 152 citations

Signaling by integrins: implications for tumorigenesis.

1993 • 150 citations

Transcriptional control by E2F

1995 • 147 citations

The ins and outs of RB: coupling gene expression to the cell cycle clock

1994 • 137 citations

Anchorage-Dependent Transcription of the Cyclin A Gene

1996 • 136 citations

Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites.

1995 • 132 citations

G1/S control of anchorage-independent growth in the fibroblast cell cycle.

1991 • 120 citations

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases.

1996 • 110 citations

Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E.

1996 • 108 citations

Arrest of 3T3 cells in G1 phase in suspension culture

1976 • 96 citations

The retinoblastoma protein and its relatives

1995 • 62 citations

The retinoblastoma tumor suppressor protein

1995 • 40 citations

An anchorage-dependent locus in the cell cycle for the growth of 3T3 cells

1981 • 24 citations

Cytoarchitecture and cell growth control

1996 • 9 citations