Three High Mobility Group-like Sequences within a 48-Base Pair Enhancer of the Col2a1 Gene Are Required for Cartilage-specific Expression in Vivo

Male development of chromosomally female mice transgenic for Sry

1991 • 2,157 citations

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

1994 • 1,573 citations

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

1994 • 1,521 citations

SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

1997 • 1,051 citations

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.

1988 • 897 citations

SOX9 directly regulates the type-ll collagen gene

1997 • 891 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

1996 • 788 citations

A male-specific role forSOX9in vertebrate sex determination

1996 • 690 citations

Toward a molecular understanding of skeletal development

1995 • 683 citations

SOX9 Binds DNA, Activates Transcription, and Coexpresses with Type II Collagen during Chondrogenesis in the Mouse

1997 • 665 citations

The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos

1995 • 648 citations

Parallel expression ofSox9 andCol2a1 in cells undergoing chondrogenesis

1997 • 496 citations

DNA Binding Activity of Recombinant SRY from Normal Males and XY Females

1992 • 454 citations

SRY AND SEX DETERMINATION IN MAMMALS

1993 • 422 citations

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

1995 • 391 citations

Definition of a consensus DNA binding site for SRY

1994 • 381 citations

Chondrocyte Differentiation

1995 • 330 citations

Ancestry and diversity of the HMG box superfamily

1993 • 328 citations

Chondrocyte-specific Enhancer Elements in the Col11a2 Gene Resemble the Col2a1 Tissue-specific Enhancer

1998 • 273 citations

Expression of the mouse α1 (II) collagen gene is not restricted to cartilage during development

1991 • 264 citations

Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone.

1995 • 242 citations

Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix.

1992 • 218 citations

Seven new members of theSoxgene family expressed during mouse development

1993 • 211 citations

The HMG-1 box protein family: classification and functional relationships

1995 • 209 citations

Sex reversal by loss of the C–terminal transactivation domain of human SOX9

1996 • 208 citations

Mutations in SOX9, the gene responsible for Campomelic dysplasia and autosomal sex reversal.

1995 • 199 citations

TheSry-related HMG box-containing geneSox6is expressed in the adult testis and developing nervous system of the mouse

1995 • 144 citations

DNA binding and bending properties of the postmeiotically expressed Sry-related protein Sox-5

1994 • 144 citations

Use of a New Rat Chondrosarcoma Cell line to Delineate a 119-Base Pair Chondrocyte-specific Enhancer Element and to Define Active Promoter Segments in the Mouse Pro-α1(II) Collagen Gene

1995 • 143 citations

A 182 bp fragment of the mouse proα1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice

1995 • 139 citations

An 18-Base-Pair Sequence in the Mouse Proα1(II) Collagen Gene Is Sufficient for Expression in Cartilage and Binds Nuclear Proteins That Are Selectively Expressed in Chondrocytes

1996 • 131 citations

Interaction between a Novel F9-Specific Factor and Octamer-Binding Proteins Is Required for Cell-Type-Restricted Activity of the Fibroblast Growth Factor 4 Enhancer

1994 • 105 citations

Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9

1996 • 96 citations

HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG.

1995 • 90 citations

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

1995 • 80 citations

Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer.

1994 • 55 citations

Netropsin, distamycin and berenil interact differentially with a high-affinity binding site for the high mobility group protein HMG-I

1990 • 39 citations

Involvement of a High-Mobility-Group Protein in the Transcriptional Activity of Herpes Simplex Virus Latency-Active Promoter 2

1996 • 37 citations