Intermediate filaments and cytoplasmic networking: new connections and more functions

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

1994 • 1,408 citations

Disruption of muscle architecture and myocardial degeneration in mice lacking desmin.

1996 • 515 citations

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1995 • 464 citations

Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration

1995 • 440 citations

Plectin deficiency results in muscular dystrophy with epidermolysis bullosa

1996 • 386 citations

The function of intermediate filaments in cell shape and cytoskeletal integrity.

1996 • 373 citations

Desmosomes and hemidesmosomes: structure and function of molecular components

1996 • 350 citations

Cardiovascular Lesions and Skeletal Myopathy in Mice Lacking Desmin

1996 • 327 citations

Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization.

1996 • 302 citations

An Essential Cytoskeletal Linker Protein Connecting Actin Microfilaments to Intermediate Filaments

1996 • 297 citations

Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins.

1994 • 283 citations

The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1

1995 • 250 citations

Intermediate filaments in disease

1995 • 248 citations

Identification of a new hemidesmosomal protein, HD1: a major, high molecular mass component of isolated hemidesmosomes.

1992 • 231 citations

Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly.

1996 • 227 citations

Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy.

1996 • 227 citations

14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor.

1996 • 209 citations

Dynamic property of intermediate filaments: Regulation by phosphorylation

1996 • 183 citations

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks.

1993 • 178 citations

Basic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctions.

1996 • 174 citations

Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

1996 • 167 citations

Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.

1995 • 161 citations

Intermediate filament-associated proteins

1991 • 112 citations

Intermediate filaments: new proteins, some answers, more questions

1995 • 102 citations

IFAP 300 is common to desmosomes and hemidesmosomes and is a possible linker of intermediate filaments to these junctions.

1994 • 92 citations

High-Affinity Binding and Localization of the Cyclic GMP-Dependent Protein Kinase with the Intermediate Filament Protein Vimentin

1994 • 63 citations

M-phase-specific phosphorylation and structural rearrangement of the cytoplasmic cross-linking protein plectin involve p34cdc2 kinase.

1996 • 56 citations

Disruption of intermediate filament organization leads to structural defects at the intersomite junction in Xenopus myotomal muscle

1995 • 36 citations

Immunocytochemical localization of protein kinases Yes and Src in amoeboid microglia in culture: association of Yes kinase with vimentin intermediate filaments.

1995 • 32 citations

Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities.

1995 • 32 citations

Identification of a second protein product of the gene encoding a human epidermal autoantigen

1994 • 18 citations