Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor

1986 • 878 citations

The purification of eukaryotic polypeptides synthesized in Escherichia coli

1986 • 838 citations

Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

1986 • 684 citations

Multiple upstream AUG codons mediate translational control of GCN4

1986 • 654 citations

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

1985 • 645 citations

Efficient infection of monkey cells with DNA of simian virus 40.

1981 • 419 citations

Bifunctional messenger RNAs in eukaryotes

1986 • 405 citations

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

1988 • 405 citations

Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin

1984 • 390 citations

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

1979 • 348 citations

Related functional domains in virus DNA polymerases.

1987 • 243 citations

Initiation of translation at internal AUG codons in mammalian cells

1984 • 231 citations

Purification of Calf Prochymosin (Prorennin) Synthesized in Escherichia Coli

1984 • 227 citations

DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein

1985 • 213 citations

Termination-reinitiation occurs in the translation of mammalian cell mRNAs.

1986 • 213 citations

Temperature-sensitive mutants of herpes simplex virus type 1: Isolation, complementation and partial characterization

1973 • 200 citations

Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene.

1986 • 191 citations

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

1985 • 172 citations

Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene

1987 • 170 citations

Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase

1977 • 152 citations

Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants.

1986 • 125 citations

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

1975 • 120 citations

Termination-Reinitiation Occurs in the Translation of Mammalian Cell mRNAs

1986 • 109 citations

Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus

1984 • 102 citations

Physical and genetic analysis of the herpes simplex virus DNA polymerase locus

1980 • 101 citations

Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid.

1982 • 100 citations

Bacteriophage PRD1 DNA polymerase: evolution of DNA polymerases.

1987 • 90 citations

Identification of a domain within the phosphoprotein of vesicular stomatitis virus that is essential for transcription in vitro.

1986 • 71 citations

Resistance of herpes simplex virus to acycloguanosine—genetic and physical analysis

1980 • 70 citations

Herpes simplex virus type I DNA polymerase. Kinetic properties of the associated 3‘-5‘ exonuclease activity and its role in araAMP incorporation.

1981 • 67 citations

Effect of Upstream Reading Frames on Translation Efficiency in Simian Virus 40 Recombinants

1986 • 66 citations

Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase.

1987 • 64 citations

Physical mapping of drug resistance mutations defines an active center of the herpes simplex virus DNA polymerase enzyme

1981 • 63 citations

Translational regulation of SV40 early mRNA defines a new viral protein

1987 • 61 citations

Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.

1985 • 52 citations

Primary structural relationships may reflect similar DNA replication strategies

1986 • 45 citations

Structural Organization and Unusual Codon Usage in the DNA Polymerase Gene from Herpes Simplex Virus Type 1

1986 • 30 citations

Viral Gene Functions Expressed and Detected by Temperature-sensitive Mutants of Herpes Simplex Virus

1974 • 26 citations

Functional expression of a cloned herpes simplex virus type 1 DNA polymerase gene

1987 • 14 citations

Deleted Work

1955 • 0 citations