Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Enzyme structure and mechanism

1978 • 2,897 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

1977 • 1,565 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

1988 • 405 citations

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

1979 • 348 citations

Modification and secretion of human interleukin 2 produced in insect cells by a baculovirus expression vector.

1985 • 286 citations

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

1988 • 278 citations

Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III.

1989 • 231 citations

Characterization of Herpes Simplex Virus-induced Deoxyribonucleic Acid Polymerase

1973 • 210 citations

Human DNA polymerase α: predicted functional domains and relationships with viral DNA polymerases

1989 • 201 citations

Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.

1988 • 190 citations

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

1985 • 172 citations

Properties of Herpes Simplex Virus DNA Polymerase and Characterization of Its Associated Exonuclease Activity

1979 • 157 citations

Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase

1977 • 152 citations

Identification of the herpes simplex virus DNA polymerase gene

1977 • 149 citations

A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.

1986 • 136 citations

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

1975 • 120 citations

Herpes simplex virus type 1 gene products required for DNA replication: identification and overexpression

1989 • 120 citations

Properties of Herpes simplex virus type 1 and type 2 DNA polymerase

1980 • 117 citations

Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus

1984 • 102 citations

Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid.

1982 • 100 citations

Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment

1983 • 100 citations

Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. I. The polA12 mutation.

1976 • 96 citations

Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase

1988 • 95 citations

Interaction between the DNA polymerase and single-stranded DNA-binding protein (infected cell protein 8) of herpes simplex virus 1.

1987 • 92 citations

DNA-binding protein associated with herpes simplex virus DNA polymerase

1985 • 89 citations

Interaction with nucleic acids and stimulation of the viral DNA polymerase by the herpes simplex virus type 1 major DNA-binding protein

1984 • 86 citations

Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants

1988 • 84 citations

NMR studies of the conformations and interactions of substrates and ribonucleotide templates bound to the large fragment of DNA polymerase I

1986 • 76 citations

Herpes simplex virus type I DNA polymerase. Kinetic properties of the associated 3‘-5‘ exonuclease activity and its role in araAMP incorporation.

1981 • 67 citations

Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase.

1987 • 64 citations

Baculovirus induction of a DNA polymerase

1981 • 60 citations

Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activity

1988 • 58 citations

Expression of herpes simplex virus type 1 DNA polymerase in Saccharomyces cerevisiae and detection of virus-specific enzyme activity in cell-free lysates

1988 • 41 citations

Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation

1988 • 39 citations

The herpes simplex virus DNA polymerase: Analysis of the functional domains

1988 • 32 citations

Kinetic and structural investigations of the replicative fidelity of the Klenow fragment

1988 • 11 citations