Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

1994 • 777 citations

Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.

1991 • 659 citations

Multi‐faceted regulation of cell differentiation by extracellular matrix

1993 • 610 citations

Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression [published erratum appears in J Cell Biol 1996 Feb;132(4):following 752]

1994 • 405 citations

Postnatal Development of the Rodent Mammary Gland

1987 • 266 citations

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

1993 • 260 citations

CELL CONTACTS IN THE MOUSE MAMMARY GLAND

1973 • 258 citations

Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.

1993 • 224 citations

neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.

1994 • 198 citations

Variation Among Species in the Endocrine Control of Mammary Growth and Function: The Roles of Prolactin, Growth Hormone, and Placental Lactogen

1986 • 197 citations

Ectopic TGFβ1 Expression in the Secretory Mammary Epithelium Induces Early Senescence of the Epithelial Stem Cell Population

1995 • 182 citations

Nuclear Factor I and Mammary Gland Factor (STAT5) Play a Critical Role in Regulating Rat Whey Acidic Protein Gene Expression in Transgenic Mice

1995 • 163 citations

Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.

1991 • 143 citations

SOME ULTRASTRUCTURAL EFFECTS OF INSULIN, HYDROCORTISONE, AND PROLACTIN ON MAMMARY GLAND EXPLANTS

1970 • 140 citations

A novel regulatory mechanism for whey acidic protein gene expression.

1989 • 137 citations

Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV‐LTR and the tetracycline responsive system

1995 • 129 citations

Comparison of the Regulation of the Whey Acidic Protein Gene with that of a Hybrid Gene Containing the Whey Acidic Protein Gene Promoter in Transgenic Mice

1988 • 121 citations

Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium.

1990 • 106 citations

Expression of alpha-lactalbumin, alpha-S1-casein, and lactoferrin genes is heterogeneous in sheep and cattle mammary tissue.

1992 • 99 citations

Over-expression of an endogenous milk protein gene in transgenic mice is associated with impaired mammary alveolar development and a milchlos phenotype

1991 • 71 citations

Cellular composition and organization of ductal buds in developing rat mammary glands: Evidence for morphological intermediates between epithelial and myoepithelial cells

1984 • 63 citations

Immunocytochemical identification of cell types in human mammary gland: variations in cellular markers are dependent on glandular topography and differentiation.

1989 • 59 citations

Breast cancer formation in transgenic animals induced by the whey acidic protein SV40 T antigen (WAP-SV-T) hybrid gene.

1993 • 57 citations

Glucocorticoid regulation of rat whey acidic protein gene expression involves hormone-induced alterations of chromatin structure in the distal promoter region.

1994 • 56 citations

Production of the mouse whey acidic protein in transgenic pigs during lactation

1991 • 54 citations

Morphology and Development of the Rat Mammary Gland

1989 • 46 citations

Whey acidic protein extrinsically expressed from the mouse mammary tumor virus long terminal repeat results in hyperplasia of the coagulation gland epithelium and impaired mammary development.

1994 • 39 citations

Regulation of human protein C gene expression by the mouse WAP promoter

1994 • 33 citations

Induction of lactogenesis in transgenic virgin pigs: evidence for gene and integration site-specific hormonal regulation.

1992 • 27 citations

The whey acidic protein

1991 • 12 citations

Regulation of expression of milk protein genes.

1993 • 8 citations

Double staining in situ study of mRNAs encoding milk proteins in the mammary gland of the tammar wallaby (Macropus eugenii)

1994 • 4 citations